Marton Olbei
@martonolbei.bsky.social
Cytokine Networks @imperialcollegeldn.bsky.social | https://cytokinelink.org/
www.imperial.ac.uk/news/article...
Summary of our recent publication on cytokine networks in ulcerative colitis
Summary of our recent publication on cytokine networks in ulcerative colitis
Decoding cellular conversations in ulcerative colitis reveals new drug targets
New research reveals previously hidden mechanisms driving inflammation and identifies new therapeutic targets, including some already showing success...
www.imperial.ac.uk
February 13, 2026 at 11:03 AM
www.imperial.ac.uk/news/article...
Summary of our recent publication on cytokine networks in ulcerative colitis
Summary of our recent publication on cytokine networks in ulcerative colitis
Reposted by Marton Olbei
Through systems immunology analysis, a team has identified potential therapeutic targets for the treatment of #UlcerativeColitis, an inflammatory bowel disease characterized by dysregulated cytokine signaling in the GI tract. #ScienceSignaling https://scim.ag/4cdvxdv
Decoding cytokine networks in ulcerative colitis to identify pathogenic mechanisms and therapeutic targets
Systems immunology reveals how cytokine-cytokine signaling is dysregulated in an inflammatory bowel disease.
scim.ag
February 6, 2026 at 4:00 PM
Through systems immunology analysis, a team has identified potential therapeutic targets for the treatment of #UlcerativeColitis, an inflammatory bowel disease characterized by dysregulated cytokine signaling in the GI tract. #ScienceSignaling https://scim.ag/4cdvxdv
Why do many UC patients struggle despite cutting-edge biologics? We suspected the answer lies not in individual cytokines, but in how they communicate as an interconnected network during disease and treatment. Our new
KorcsmarosLab paper published in Science Signaling
www.science.org/doi/10.1126/...
KorcsmarosLab paper published in Science Signaling
www.science.org/doi/10.1126/...
Decoding cytokine networks in ulcerative colitis to identify pathogenic mechanisms and therapeutic targets
Systems immunology reveals how cytokine-cytokine signaling is dysregulated in an inflammatory bowel disease.
www.science.org
February 5, 2026 at 11:28 AM
Why do many UC patients struggle despite cutting-edge biologics? We suspected the answer lies not in individual cytokines, but in how they communicate as an interconnected network during disease and treatment. Our new
KorcsmarosLab paper published in Science Signaling
www.science.org/doi/10.1126/...
KorcsmarosLab paper published in Science Signaling
www.science.org/doi/10.1126/...
Reposted by Marton Olbei
Systems immunology reveals how cytokine-cytokine signaling is dysregulated in an inflammatory bowel disease @martonolbei.bsky.social @imperialcollegeldn.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
February 3, 2026 at 10:16 PM
Systems immunology reveals how cytokine-cytokine signaling is dysregulated in an inflammatory bowel disease @martonolbei.bsky.social @imperialcollegeldn.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Marton Olbei
🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
September 17, 2025 at 1:10 PM
🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
Excited to share that I started a new chapter in my career as a Teaching Fellow at Imperial College London! I really enjoy teaching, and look forward to the opportunities and challenges ahead.
July 3, 2025 at 12:53 PM
Excited to share that I started a new chapter in my career as a Teaching Fellow at Imperial College London! I really enjoy teaching, and look forward to the opportunities and challenges ahead.
Reposted by Marton Olbei
📄 Update on our preprint about Gene Regulatory Net (GRN) benchmarking 📄
We have included the original and decoupled version of SCENIC+, added a new metric and two more databases. Dictys and SCENIC+ outperformed others, but still performed poorly in causal mechanistic tasks.
doi.org/10.1101/2024... 👇
We have included the original and decoupled version of SCENIC+, added a new metric and two more databases. Dictys and SCENIC+ outperformed others, but still performed poorly in causal mechanistic tasks.
doi.org/10.1101/2024... 👇
March 14, 2025 at 10:34 AM
📄 Update on our preprint about Gene Regulatory Net (GRN) benchmarking 📄
We have included the original and decoupled version of SCENIC+, added a new metric and two more databases. Dictys and SCENIC+ outperformed others, but still performed poorly in causal mechanistic tasks.
doi.org/10.1101/2024... 👇
We have included the original and decoupled version of SCENIC+, added a new metric and two more databases. Dictys and SCENIC+ outperformed others, but still performed poorly in causal mechanistic tasks.
doi.org/10.1101/2024... 👇
Excited to share our work on UC cytokine networks at #ECCO2025.
Come by poster P0104 if you are interested in:
- how cytokines regulate each other in UC
- the role of TL1A in treatment-naive UC
- how we could use this approach to identify new drug targets
www.biorxiv.org/content/10.1...
Come by poster P0104 if you are interested in:
- how cytokines regulate each other in UC
- the role of TL1A in treatment-naive UC
- how we could use this approach to identify new drug targets
www.biorxiv.org/content/10.1...
Decoding Cytokine Networks in Ulcerative Colitis to Identify Pathogenic Mechanisms and Therapeutic Targets
Ulcerative colitis (UC) is a chronic inflammatory disorder of the gastrointestinal tract characterised by dysregulated cytokine signalling. Despite the advent of advanced therapies targeting cytokine ...
www.biorxiv.org
February 21, 2025 at 11:18 AM
Excited to share our work on UC cytokine networks at #ECCO2025.
Come by poster P0104 if you are interested in:
- how cytokines regulate each other in UC
- the role of TL1A in treatment-naive UC
- how we could use this approach to identify new drug targets
www.biorxiv.org/content/10.1...
Come by poster P0104 if you are interested in:
- how cytokines regulate each other in UC
- the role of TL1A in treatment-naive UC
- how we could use this approach to identify new drug targets
www.biorxiv.org/content/10.1...
Reposted by Marton Olbei
We present NetworkCommons, a unified platform 🪐 for network biology, providing access to omics data, knowledge, and contextualization methods, all with a consistent API 👇🧵
Paper: doi.org/10.1101/2024...
Docs: networkcommons.readthedocs.io
Paper: doi.org/10.1101/2024...
Docs: networkcommons.readthedocs.io
November 26, 2024 at 9:44 AM
We present NetworkCommons, a unified platform 🪐 for network biology, providing access to omics data, knowledge, and contextualization methods, all with a consistent API 👇🧵
Paper: doi.org/10.1101/2024...
Docs: networkcommons.readthedocs.io
Paper: doi.org/10.1101/2024...
Docs: networkcommons.readthedocs.io