Marc Bonten
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marcbonten.bsky.social
Marc Bonten
@marcbonten.bsky.social
2.8K followers 390 following 99 posts
Professor of Molecular Epidemiology of Infectious Diseases @UMCUtrecht. CEO of the European Clinical Research Alliance on Infectious Diseases, @ecraid. All opinions my own.
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Reposted by Marc Bonten
ecraid.bsky.social
We are very pleased to announce Lennie Derde as Ecraid's new Chief Executive Officer effective 1 January 2026. She will succeed Ecraid’s co-founder @marcbonten.bsky.social

Read more 👉 ecraid.eu/articles/len...

@umcutrecht.bsky.social @ec.europa.eu @horizoneu.bsky.social
November 12, 2025 at 1:43 PM
marcbonten.bsky.social
💉 Read my latest science blog on non-specific effects of BCG, a vaccine intended to prevent tuberculosis. 👇

letstalkscience.eu/2025/11/04/l...
Lost in translation over BCG vaccination - Let's Talk Science with Marc Bonten
Last week I engaged in a discussion on X about the validity of this recent publication on a randomized controlled trial (RCT) on neonatal mortality in newborns. As a background: BCG vaccination is rou...
letstalkscience.eu
November 4, 2025 at 3:38 PM
marcbonten.bsky.social
We actually discovered over-the-counter selling of antibiotics
@cmicomms.bsky.social
September 11, 2025 at 5:03 PM
marcbonten.bsky.social
Now online: our commentary on the topic of initial antibiotic therapy in patients hospitalized with pneumonia. 👇

💣 Spoiler alert: we need to change rules if we want the best therapy for our patients.

www.clinicalmicrobiologyandinfection.org/action/showP...
Empiric antibiotics for moderate-severe community-Acquired Pneumonia: We ought to serve patients better!
Each day thousands of patients are hospitalized worldwide with Community-Acquired Pneumonia (CAP), either radiologically confirmed or presumed based on clinical symptoms only, and each day physicians ...
www.clinicalmicrobiologyandinfection.org
September 10, 2025 at 9:50 AM
marcbonten.bsky.social
Can acute COVID-19 awaken dormant cancer cells?

An important study, recently published.

My blog on the translation of experimental findings in mice to observational population-based data in men. 👇

letstalkscience.eu/2025/08/18/c...
Can acute COVID-19 awaken dormant cancer cells? - Let's Talk Science with Marc Bonten
Yes, according to this study, which was the talk of the summer. In short: In mice experimental lung infection with SARS-CoV-2 and influenza reactivated dormant breast cancer cells, rapidly leading to ...
letstalkscience.eu
August 18, 2025 at 12:54 PM
marcbonten.bsky.social
I"Het is waar dat geen enkel gesprek perfect is en dat er altijd een risico is dat een discussie uit de hand loopt. Daarom is het nodig dat de universiteit zorgt voor ondersteuning om veilige klaslokalen te creëren waarin gepassioneerde docenten en open-minded studenten met elkaar in gesprek gaan."
May 19, 2025 at 12:44 PM
Reposted by Marc Bonten
catgaohow.bsky.social
Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025
May 18, 2025 at 10:44 PM
marcbonten.bsky.social
Now out: complete analysis of the immune modulation for acute COVID-19 in REMAP-CAP study. Interleukin-6 receptor antagonists (tozilizumab & sarlilumab) did better than standard of care, interleukin-1 receptor antagonist (anakinra) did not. @lenniederde.bsky.social

thorax.bmj.com/content/thor...
thorax.bmj.com
May 19, 2025 at 8:17 AM
Reposted by Marc Bonten
cmicomms.bsky.social
🎙️ Just published a new #Communicable episode: Communicable E27: Late-breaker trials...

Hosted by Marc Bonten @marcbonten.bsky.social
Josh Davis @gurujosh.bsky.social
Erin McCreary @erinmccreary.bsky.social
Emily McDonald @dremilymcd.bsky.social

Listen here:

#IDSky #Clinmicro #MedSky
Communicable E27: Late-breaker trials at ESCMID Global: Should they change your practice? - part 1
This episode of Communicable takes on a special format where editors of...
share.transistor.fm
May 18, 2025 at 10:01 PM
marcbonten.bsky.social
BumblebeeJoe: the gift that keeps on giving.
marcveld.bsky.social Marc Veldhoen @marcveld.bsky.social · May 13
Wanneer je de verkeerde vraag stelt en vervolgens het antwoord verspreidt zonder de benodigde context en kennis.

Wat is er fout?
1/5
May 14, 2025 at 9:33 AM
Reposted by Marc Bonten
claudiazelf.bsky.social
Ik vind deze campagne op zijn minst een broodnodig signaal.
Doe mee! actie.degoedezaak.org/petitions/mo...
Teken voor een motie van wantrouwen tegen minister Faber
De ondertekenaars van deze petitie laten zien dat het Nederlandse volk klaar is met een minister die de hand boven het hoofd gehouden wordt om de coalitie bij elkaar te houden. Dit terwijl de minister...
actie.degoedezaak.org
May 11, 2025 at 5:40 AM
Reposted by Marc Bonten
pauljbelcher.bsky.social
🏥 1 in 3 doctors in Europe are older than 55. Which countries are most at risk from ageing workforces?

'Poor work-life balance, high administrative burdens, and inadequate pay in some countries drive younger doctors to emigrate or leave the profession altogether.'

www.euronews.com/health/2025/...
May 11, 2025 at 5:50 AM
marcbonten.bsky.social
Debated for 40 years: Selective Decontamination of the Digestive tract in ICU patients (antibiotics to prevent ICU-acquired infections). My editorial to Josh Davis @gurujosh.bsky.social and Allen Cheng @peripatetical.bsky.social pro-con in @cmicomms.bsky.social.

www.cmi-comms.com/article/S295...
The Frank-Starling law of Selective Digestive Decontamination
More than hundred years ago a series of experiments demonstrated that increased strechting of heart muscles (through higher venous return) increased stroke volume (cardiac output). But not endlessly, ...
www.cmi-comms.com
May 9, 2025 at 6:01 AM
Reposted by Marc Bonten
enirenberg.bsky.social
Critical new piece from @helenbranswell.bsky.social. This is a crisis point in vaccine regulation.
8 possible indicators of how RFK Jr.’s HHS will handle vaccine policy
Here are eight possible indicators of how health secretary Robert F. Kennedy Jr. may handle U.S. vaccine policy in coming weeks.
www.statnews.com
April 30, 2025 at 2:47 PM
Reposted by Marc Bonten
bencollins.bsky.social
RFK Jr.: The teen cum is insufficient. I need more teen cum.
atrupar.com Aaron Rupar @atrupar.com · Apr 23
RFK Jr: An American teenager today has less testosterone than a 68 year old man. Sperm counts are down 50 percent.

WATTERS: Wait -- an American teenager has less testosterone than a 68 year old man?

RFK JR: That's right
April 23, 2025 at 12:47 AM
Reposted by Marc Bonten
freereed59.net
www.theguardian.com/commentisfre... we need to ensure these views do not gain traction in the UK
RFK’s statements prove autistic people and their families everywhere should fear Trump and his allies | John Harris
The idea that autism is some aberration that can be cured is typical of a movement that celebrates simplistic thinking and loathes human difference, says Guardian columnist John Harris
www.theguardian.com
April 21, 2025 at 8:42 AM
Reposted by Marc Bonten
samanthahoriz0n.bsky.social
Well that was fast, Bluesky 🤦‍♀️
April 21, 2025 at 9:04 AM
marcbonten.bsky.social
Trump administration now after editors of medical journals….
carlbergstrom.com Carl T. Bergstrom @carlbergstrom.com · Apr 18
Meanwhile, DOJ lawyers are threatening medical journals for not providing adequate "viewpoint diversity" and for misinforming their readership, which I suppose means not publishing enough of the stupid shit that RFK Jr., JB, etc. keep saying.

This is an outrageous First Amendment violation.
Medical Journals Get Letters From DOJ
At least three journals received letters from a U.S. Attorney asking about 'competing viewpoints'
www.medpagetoday.com
April 21, 2025 at 6:41 AM
Reposted by Marc Bonten
pauljbelcher.bsky.social
“What is happening now is not normal politics. We’re seeing an assault on the fundamental institutions of our civic life, things we should all swear loyalty to — Democrat, independent or Republican.

It’s time for a comprehensive national civic uprising”

#HandsOff

www.nytimes.com/2025/04/17/o...
Opinion | What’s Happening Is Not Normal. America Needs an Uprising That Is Not Normal. (Gift Article)
It will take a concerted effort by every sector of our society to respond to Trumpism’s threat.
www.nytimes.com
April 20, 2025 at 5:24 AM
marcbonten.bsky.social
Excellent 🧵debunking the 5 “facts” of the lab-leak theory, now the official thruth according to the White House.
adamjkucharski.bsky.social Adam Kucharski @adamjkucharski.bsky.social · Apr 19
The White House has turned COVID.gov from a public health resource into a politically charged platform promoting the lab-leak theory and attacking specific scientists and the pandemic response in general. Let’s fact check its 5 headline claims… 🧵
The virus possesses a biological characteristic that is not found in nature. 2. Data shows that all COVID-19 cases stem from a single introduction into humans. This runs contrary to previous pandemics where there were multiple spillover events. 3. Wuhan is home to China’s foremost SARS research lab, which has a history of conducting gain-of-function research (gene altering and organism supercharging) at inadequate biosafety levels. 4. Wuhan Institute of Virology (WIV) researchers were sick with COVID-like symptoms in the fall of 2019, months before COVID-19 was discovered at the wet market. 5. By nearly all measures of science, if there was evidence of a natural origin it would have already surfaced. But it hasn’t.
April 21, 2025 at 6:29 AM
Reposted by Marc Bonten
altcdc.altgov.info
HHS Eliminated Programs - Updated

Here is an updated list of all programs eliminated in the 2026 HHS Budget. Reach out if you have information or clarity on the cuts.

These cuts will impact Every Single American.

Email altcdc1@pm.me for PDF and xlsx.
A list of all agencies and programs the Trump administration is seeking to eliminate. An accessible PDF is available from altCDC. Email altcdc1@pm.me.
April 21, 2025 at 3:17 AM
marcbonten.bsky.social
Now on stage #ESCMIDGlobal2025 dr Cristina Prat presenting data from the ongoing PNEUMO study that aims to quantify the seroprevalence of pneumococcal pneumonia and invasive disease. @ecraid.bsky.social @umcutrecht.bsky.social
April 13, 2025 at 10:38 AM
marcbonten.bsky.social
Nice to see the results from the @ecraid.bsky.social POS-cUTI presented by Chantal Kats, treatment duration of complicated UTI is very heterogeneous and some baseline characteristics are prognostic for durations of >14 days. Results from 1st 1000 patients, currently >3000 in the study.
April 13, 2025 at 9:27 AM
marcbonten.bsky.social
This day is great, even though it just started. I'm still on X (no longer posting) and I had 1 new follower (since weeks): Stevie Nicks! Enjoy the day.

www.youtube.com/watch?v=XYgL...
Stevie Nicks - Sara (Live In Chicago)
YouTube video by Stevie Nicks
www.youtube.com
April 13, 2025 at 6:45 AM
Reposted by Marc Bonten
erinmccreary.bsky.social
@steventong.bsky.social presents the results of the PSSA domain of the SNAP 🫰 trial - the worlds largest trial of staph aureus bacteremia - at #ESCMID2025

fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA
April 12, 2025 at 2:45 PM