Malachi Griffith
@malachigriffith.bsky.social
Professor, Department of Medicine and McDonell Genome Institute @ Washington University. Specializing in Bioinformatics, Genomics, and Cancer. http://griffithlab.org/
The open access resource CIViCdb.org (Clinical Interpretation of Variants in Cancer) has just passed 11,000 evidence statements! That's 11k times a domain expert reviewed a paper and used the CIViC curation interface to create a structured entry for clinical relevance of a specific somatic variant.
CIViC - Clinical Interpretation of Variants in Cancer
CIViCdb.org
November 24, 2025 at 9:08 PM
The open access resource CIViCdb.org (Clinical Interpretation of Variants in Cancer) has just passed 11,000 evidence statements! That's 11k times a domain expert reviewed a paper and used the CIViC curation interface to create a structured entry for clinical relevance of a specific somatic variant.
Reposted by Malachi Griffith
Our first curated draft somatic structural variant benchmark for the new GIAB PDAC tumor cell line HG008-T is at ftp-trace.ncbi.nlm.nih.gov/ReferenceSam..., based on extensive short+long read sequencing data described in doi.org/10.1101/2024.... Feedback to improve future versions is very welcome!
Index of /ReferenceSamples/giab/data_somatic/HG008/Liss_lab/analysis/NIST_HG008-T_somatic-stvar_DraftBenchmark_V0.1-20241219
ftp-trace.ncbi.nlm.nih.gov
December 20, 2024 at 6:04 PM
Our first curated draft somatic structural variant benchmark for the new GIAB PDAC tumor cell line HG008-T is at ftp-trace.ncbi.nlm.nih.gov/ReferenceSam..., based on extensive short+long read sequencing data described in doi.org/10.1101/2024.... Feedback to improve future versions is very welcome!