Lyme Disease Biobank
@lymebiobank.bsky.social
Non-profit providing human biological samples to investigators developing better tests for Lyme and tick-borne infections. Whole blood, serum, plasma, & urine available from people with early Lyme, persistent Lyme, & controls. We also have a tissue bank.
So grateful for Biobank research participants and families who make this resource possible. I'm honored to work with amazing investigators and collaborators working on novel diagnostics for Lyme! We are making progress on this complex disease.
November 26, 2025 at 6:12 PM
So grateful for Biobank research participants and families who make this resource possible. I'm honored to work with amazing investigators and collaborators working on novel diagnostics for Lyme! We are making progress on this complex disease.
Check out @lymenews.bsky.social MyLymeData 2025 Research Chartbook! Great graphical representation of registry data and what we are learning from Lyme patients. What an important resource for the community. 10 years of data and counting.
This year marks a major milestone for the MyLymeData patient registry—our 10th anniversary.
To celebrate, we’re publishing the MyLymeData 2025 Research Chartbook—a visual summary of a decade of groundbreaking research, collaboration, and progress.
READ MORE: www.lymedisease.org/mylymedata-2...
To celebrate, we’re publishing the MyLymeData 2025 Research Chartbook—a visual summary of a decade of groundbreaking research, collaboration, and progress.
READ MORE: www.lymedisease.org/mylymedata-2...
October 30, 2025 at 2:06 PM
Check out @lymenews.bsky.social MyLymeData 2025 Research Chartbook! Great graphical representation of registry data and what we are learning from Lyme patients. What an important resource for the community. 10 years of data and counting.
Funding opp!
2 X 150K awards: 1 on Lyme disease and a new award on tick-borne pathogens (bacterial or parasitic)
Academic or private-sector researchers at the post-doctoral through associate professor level (or equivalent)
Due: February 15, 2026, at 11:59pm PT
www.bayarealyme.org/blog/bay-are...
2 X 150K awards: 1 on Lyme disease and a new award on tick-borne pathogens (bacterial or parasitic)
Academic or private-sector researchers at the post-doctoral through associate professor level (or equivalent)
Due: February 15, 2026, at 11:59pm PT
www.bayarealyme.org/blog/bay-are...
Bay Area Lyme Foundation Opens Applications for 2026 Emerging Leader Awards and Research Grants - Bay Area Lyme Foundation
FOR IMMEDIATE RELEASE Bay Area Lyme Foundation Opens Applications for 2026 Emerging Leader Awards and Research Grants Annual program to fund two $150,000 grants to revolutionize diagnosis and treatmen...
www.bayarealyme.org
October 22, 2025 at 4:48 PM
Funding opp!
2 X 150K awards: 1 on Lyme disease and a new award on tick-borne pathogens (bacterial or parasitic)
Academic or private-sector researchers at the post-doctoral through associate professor level (or equivalent)
Due: February 15, 2026, at 11:59pm PT
www.bayarealyme.org/blog/bay-are...
2 X 150K awards: 1 on Lyme disease and a new award on tick-borne pathogens (bacterial or parasitic)
Academic or private-sector researchers at the post-doctoral through associate professor level (or equivalent)
Due: February 15, 2026, at 11:59pm PT
www.bayarealyme.org/blog/bay-are...
This is another single-tier test that I'm really excited about. We require sample users to provide results before we break the blind on the samples. This test from InBio and Kephera's Hybrid ELISA both look really good in early Lyme (~ 1 week) where current serology tests are insensitive.
New study in @jclinmicroeic.bsky.social shows a new multiplex Lyme serology test is more sensitive than standard two-tier serology tests! Detected more cases w EM at 7 days. Great collaboration with Pete Gwynne @tuftslyme.bsky.social journals.asm.org/doi/10.1128/...
The multiplexed single-tier InBios Lyme Detect Multiplex ELISA is more sensitive than standard two-tier tests in the early stages of Lyme disease | Journal of Clinical Microbiology
During initial Lyme disease infection, existing diagnostic tests have poor sensitivity,
resulting in a high number of false-negative tests. This is due to the lag between
infection and a robust immune...
journals.asm.org
October 9, 2025 at 6:48 PM
This is another single-tier test that I'm really excited about. We require sample users to provide results before we break the blind on the samples. This test from InBio and Kephera's Hybrid ELISA both look really good in early Lyme (~ 1 week) where current serology tests are insensitive.
New study in @jclinmicroeic.bsky.social shows a new multiplex Lyme serology test is more sensitive than standard two-tier serology tests! Detected more cases w EM at 7 days. Great collaboration with Pete Gwynne @tuftslyme.bsky.social journals.asm.org/doi/10.1128/...
The multiplexed single-tier InBios Lyme Detect Multiplex ELISA is more sensitive than standard two-tier tests in the early stages of Lyme disease | Journal of Clinical Microbiology
During initial Lyme disease infection, existing diagnostic tests have poor sensitivity,
resulting in a high number of false-negative tests. This is due to the lag between
infection and a robust immune...
journals.asm.org
October 9, 2025 at 6:45 PM
New study in @jclinmicroeic.bsky.social shows a new multiplex Lyme serology test is more sensitive than standard two-tier serology tests! Detected more cases w EM at 7 days. Great collaboration with Pete Gwynne @tuftslyme.bsky.social journals.asm.org/doi/10.1128/...
Question for people who frequently publish - I just got a notification that our recent Lyme disease article published in July in Frontiers in Medicine had 500 downloads? Is that good? Thanks! www.frontiersin.org/journals/med...
Frontiers | Lyme Disease Biobank: 10 years of 3 month follow-up visits from 2014 to 2023
IntroductionLyme Disease Biobank (LDB) enrolls participants with signs and symptoms of early Lyme disease (LD) from endemic areas and makes samples available...
www.frontiersin.org
September 21, 2025 at 9:47 PM
Question for people who frequently publish - I just got a notification that our recent Lyme disease article published in July in Frontiers in Medicine had 500 downloads? Is that good? Thanks! www.frontiersin.org/journals/med...
I'm really excited about the single-tier assays. There are several in development that have positive results in early Lyme samples with EM that STTT and MTTT miss. These single-tier tests are more sensitive without sacrificing specificity and take less time/resources to run.
#TickSky
#MicroSky
#TickSky
#MicroSky
Kephera's single-tier Lyme test published in @ASM JCM - Hybrid ELISA approach requires binding to VlsE AND C6. More sensitive in early disease while maintaining specificity. journals.asm.org/doi/10.1128/...
A novel single-tier serologic test to diagnose all stages of Lyme disease | Journal of Clinical Microbiology
The diagnosis of Lyme disease, a tick-borne spirochetal infection caused by Borrelia burgdorferi sensu lato, is subject to two major limitations: the need for a two-tier serologic testing algorithm to provide adequate specificity, and the low sensitivity ...
journals.asm.org
August 20, 2025 at 2:27 PM
Kephera's single-tier Lyme test published in @ASM JCM - Hybrid ELISA approach requires binding to VlsE AND C6. More sensitive in early disease while maintaining specificity. journals.asm.org/doi/10.1128/...
A novel single-tier serologic test to diagnose all stages of Lyme disease | Journal of Clinical Microbiology
The diagnosis of Lyme disease, a tick-borne spirochetal infection caused by Borrelia burgdorferi sensu lato, is subject to two major limitations: the need for a two-tier serologic testing algorithm to provide adequate specificity, and the low sensitivity ...
journals.asm.org
August 20, 2025 at 2:19 PM
Kephera's single-tier Lyme test published in @ASM JCM - Hybrid ELISA approach requires binding to VlsE AND C6. More sensitive in early disease while maintaining specificity. journals.asm.org/doi/10.1128/...
Article from @medscape.com about LymeSeek - a new Lyme diagnostic in development from Aces Diagnostics plus @bayarealyme.bsky.social biobank data showing how unreliable available tests are in early disease. (They miss 7 out of 10 early Lyme cases) www.medscape.com/viewarticle/...
New Lyme Blood Test Bests Standard Diagnostics
The single-tier test uses artificial intelligence to accurately detect Lyme disease from the first few weeks of infection through 1 year post-diagnosis.
www.medscape.com
August 5, 2025 at 2:03 PM
Article from @medscape.com about LymeSeek - a new Lyme diagnostic in development from Aces Diagnostics plus @bayarealyme.bsky.social biobank data showing how unreliable available tests are in early disease. (They miss 7 out of 10 early Lyme cases) www.medscape.com/viewarticle/...
New research from @gomes-solecki.bsky.social and team on using immunoglobulin class and IgG isotypes to distinguish different stages of Lyme disease. Could help identify early Lyme cases which are often missed by current serology tests. journals.asm.org/doi/10.1128/...
Class and isotype of VlsE-specific antibody differentiates Lyme disease stage | Journal of Clinical Microbiology
The order of switching between the immunoglobulin heavy chain (Fc) is time dependent,
progressing from IgM/D to IgG3/IgG1/IgA1/IgG2/IgG4 and later to IgE/IgA2. In this
study, we show that B. burgdorfe...
journals.asm.org
July 16, 2025 at 2:33 PM
New research from @gomes-solecki.bsky.social and team on using immunoglobulin class and IgG isotypes to distinguish different stages of Lyme disease. Could help identify early Lyme cases which are often missed by current serology tests. journals.asm.org/doi/10.1128/...
Want to learn more about the biobank? Check out my talk about our sample collection, diagnostics in development using these samples, and finding Borrelia in tissue! Shout out to @livlyme.bsky.social for a great Summit and making these talks available!
🎥 BIG NEWS! 🎥
The 2025 LivLyme Scientific Summit speaker videos are now LIVE — and they’re completely FREE to watch!
Hear from top scientists, physicians, and advocates as they share the latest research, breakthroughs, and hope in the fight against Lyme and TBDs.
📲 Watch now at LivLymeFoundation.org
The 2025 LivLyme Scientific Summit speaker videos are now LIVE — and they’re completely FREE to watch!
Hear from top scientists, physicians, and advocates as they share the latest research, breakthroughs, and hope in the fight against Lyme and TBDs.
📲 Watch now at LivLymeFoundation.org
July 15, 2025 at 2:00 PM
Want to learn more about the biobank? Check out my talk about our sample collection, diagnostics in development using these samples, and finding Borrelia in tissue! Shout out to @livlyme.bsky.social for a great Summit and making these talks available!
Great interview with @tuftslyme.bsky.social Linden Hu! This really is the year for ticks and Lyme disease.....
Muscle pain with a side of brain fog: Dealing with Lyme disease isn’t a fun time, and the ticks that carry it are proliferating. An immunologist shares the ongoing quest for a vaccine against the disease.
Why Don’t We Have A Vaccine For Lyme Disease?
Tick seasons are getting worse, raising concerns about the risk of Lyme disease. Dogs can get vaccinated for it. Why can't humans?
www.sciencefriday.com
July 13, 2025 at 5:43 PM
Great interview with @tuftslyme.bsky.social Linden Hu! This really is the year for ticks and Lyme disease.....
New paper from Jorge Cervantes and team in J Investig Med looking at cytokines in acute and convalescent samples from patients with early acute Lyme. At convalescence, some cytokines returned to normal levels, some were elevated, and others were reduced.
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
EXPRESS: Key inflammatory mediators drive the resolution of acute Lyme disease - Jorge L. Cervantes, Shahrukh Chaudhry, Jose Barragan, Idris Akinlusi, Ted Zhao, Ryan Graff, Bo-young Hong, 2025
Lyme disease is an inflammatory disease in response to Borrelia burgdorferi infection. We analyzed cytokines in sera from acute and convalescent LD patients, an...
journals.sagepub.com
June 20, 2025 at 10:02 PM
New paper from Jorge Cervantes and team in J Investig Med looking at cytokines in acute and convalescent samples from patients with early acute Lyme. At convalescence, some cytokines returned to normal levels, some were elevated, and others were reduced.
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
Congratulations! @lymenews.bsky.social MyLymeData is an incredibly important resource in #LymeDisease.
Our latest issue celebrates MyLymeData’s 10th anniversary, highlighting its impact in reshaping Lyme disease research. It also features news updates and powerful first-person accounts of resilience and recovery from Lyme and other tick-borne diseases. www.lymedisease.org/members/lyme...
2025 Summer LymeTimes - LymeDisease.org Member Community
LymeTimes Summer 2025 - 10 Years of MyLymeData: A Patient-Driven Revolution in Lyme Disease Research
www.lymedisease.org
June 12, 2025 at 3:07 PM
Congratulations! @lymenews.bsky.social MyLymeData is an incredibly important resource in #LymeDisease.
New study from long time collaborator Neal Woodbury and team at #ASU identifies #biomarkers using #Biobank samples that distinguish #LymeDisease from other febrile illnesses. #diagnostics
www.frontiersin.org/journals/imm...
www.frontiersin.org/journals/imm...
Frontiers | Serologic biomarker discovery for differentiating Lyme disease from diseases with similar clinical symptoms using broad profiling of antibody binding
IntroductionLyme disease (LD) is a tick-borne disease that is a substantial public health burden with estimated about 0.5 million new cases per year in the U...
www.frontiersin.org
June 4, 2025 at 7:03 PM
New study from long time collaborator Neal Woodbury and team at #ASU identifies #biomarkers using #Biobank samples that distinguish #LymeDisease from other febrile illnesses. #diagnostics
www.frontiersin.org/journals/imm...
www.frontiersin.org/journals/imm...
Read more about Meghan Bradshaw - she is amazing - and she is a scientist.
After 18 joint replacements in 6 years, she's now a fierce Lyme advocate @lyme_action www.lymedisease.org/18-joint-rep... #LymeDiseaseAwarenessMonth
May 23, 2025 at 9:07 PM
Read more about Meghan Bradshaw - she is amazing - and she is a scientist.
Reposted by Lyme Disease Biobank
Opportunity to tell your Senators and Representative that funding for Lyme and tick-borne disease is important. Letters can be customized! #LymeSky #TickSky
app.oneclickpolitics.com/campaign-pag...
app.oneclickpolitics.com/campaign-pag...
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
app.oneclickpolitics.com
April 23, 2025 at 2:07 PM
Opportunity to tell your Senators and Representative that funding for Lyme and tick-borne disease is important. Letters can be customized! #LymeSky #TickSky
app.oneclickpolitics.com/campaign-pag...
app.oneclickpolitics.com/campaign-pag...
Reposted by Lyme Disease Biobank
Don't miss @livlyme.bsky.social summit on May 3. At 12:45 EST/9:45 PST, I'll be talking about @bayarealyme.bsky.social #LymeDisease #biobank - details on 10 years of collection plus recently published work in diagnostics and pathogenesis. Registration is free #TickSky #MicroSky
The LivLyme Summit 2025 is going virtual on May 3rd — packed w/ a powerhouse lineup of Lyme experts, scientists, & advocates from across the 🌎. From chronic Lyme to cutting-edge therapies, don’t miss this FREE, info-filled day of science, and action.
Register now at Livlyme.org. 💚✅
Register now at Livlyme.org. 💚✅
April 28, 2025 at 3:19 PM
Don't miss @livlyme.bsky.social summit on May 3. At 12:45 EST/9:45 PST, I'll be talking about @bayarealyme.bsky.social #LymeDisease #biobank - details on 10 years of collection plus recently published work in diagnostics and pathogenesis. Registration is free #TickSky #MicroSky
Excited to hear from @jutraslab.bsky.social and @immunofever.bsky.social this Saturday @livlyme.bsky.social. I'm presenting on @bayarealyme.bsky.social Biobank's blood and tissue collection and recently published results. #LymeDisease #MicroSky #TickSky
The 6th Annual LivLyme Summit is virtual on Saturday, May 3, 2025!
Join us for a powerful day of expert talks on Lyme disease, co-infections, groundbreaking treatments, and patient care—from world-renowned scientists, & physicians.
This event is free to attend.
Register now at LivLymeFoundation.org
Join us for a powerful day of expert talks on Lyme disease, co-infections, groundbreaking treatments, and patient care—from world-renowned scientists, & physicians.
This event is free to attend.
Register now at LivLymeFoundation.org
April 29, 2025 at 2:16 PM
Excited to hear from @jutraslab.bsky.social and @immunofever.bsky.social this Saturday @livlyme.bsky.social. I'm presenting on @bayarealyme.bsky.social Biobank's blood and tissue collection and recently published results. #LymeDisease #MicroSky #TickSky
Don't miss @livlyme.bsky.social summit on May 3. At 12:45 EST/9:45 PST, I'll be talking about @bayarealyme.bsky.social #LymeDisease #biobank - details on 10 years of collection plus recently published work in diagnostics and pathogenesis. Registration is free #TickSky #MicroSky
The LivLyme Summit 2025 is going virtual on May 3rd — packed w/ a powerhouse lineup of Lyme experts, scientists, & advocates from across the 🌎. From chronic Lyme to cutting-edge therapies, don’t miss this FREE, info-filled day of science, and action.
Register now at Livlyme.org. 💚✅
Register now at Livlyme.org. 💚✅
April 28, 2025 at 3:19 PM
Don't miss @livlyme.bsky.social summit on May 3. At 12:45 EST/9:45 PST, I'll be talking about @bayarealyme.bsky.social #LymeDisease #biobank - details on 10 years of collection plus recently published work in diagnostics and pathogenesis. Registration is free #TickSky #MicroSky
Opportunity to tell your Senators and Representative that funding for Lyme and tick-borne disease is important. Letters can be customized! #LymeSky #TickSky
app.oneclickpolitics.com/campaign-pag...
app.oneclickpolitics.com/campaign-pag...
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
app.oneclickpolitics.com
April 23, 2025 at 2:07 PM
Opportunity to tell your Senators and Representative that funding for Lyme and tick-borne disease is important. Letters can be customized! #LymeSky #TickSky
app.oneclickpolitics.com/campaign-pag...
app.oneclickpolitics.com/campaign-pag...
Reposted by Lyme Disease Biobank
Center for Lyme Action launched a campaign to restore funding to CDMRP TBDRP (Tick-borne Disease Research Program). Consider making your voice heard. #TickBsky #MicroBsky
app.oneclickpolitics.com/campaign-pag...
app.oneclickpolitics.com/campaign-pag...
Contact Your U.S. Representative to Restore and Fund DOD’s Tick-borne Disease Research Program
Contact Your U.S. Representative to Restore and Fund DOD’s Tick-borne Disease Research Program
app.oneclickpolitics.com
April 9, 2025 at 11:17 PM
Center for Lyme Action launched a campaign to restore funding to CDMRP TBDRP (Tick-borne Disease Research Program). Consider making your voice heard. #TickBsky #MicroBsky
app.oneclickpolitics.com/campaign-pag...
app.oneclickpolitics.com/campaign-pag...
New article using Raman spectroscopy to distinguish early #Lyme disease from controls. Project used biobank samples and was funded by @bayarealyme.bsky.social #diagnostics onlinelibrary.wiley.com/doi/10.1002/...
External Validation of Raman Spectroscopy for Lyme Disease Diagnostics
Our results show the potential of Raman spectroscopy integrated with machine learning as a rapid diagnostic platform for Lyme disease.
onlinelibrary.wiley.com
February 21, 2025 at 4:35 PM
New article using Raman spectroscopy to distinguish early #Lyme disease from controls. Project used biobank samples and was funded by @bayarealyme.bsky.social #diagnostics onlinelibrary.wiley.com/doi/10.1002/...