Léa Monge-Waleryszak
@lwaleryszak.bsky.social
PhD in Plant-Microbe Molecular Interactions
Pinned
Three ARID proteins involved in chromatin remodeling PEAT complexes are targeted by the Ralstonia solanacearum effector PopP2 and contribute to bacterial wilt disease
The Ralstonia solanacearum effector PopP2 is a YopJ family acetyltransferase. PopP2 is known to dampen basal immune responses by acetylating defensive WRKY transcription factors, and probably by targ...
doi.org
Love uncovering effector virulence strategies! 😀
Our work on PopP2 targeting core components of the PEAT chromatin-remodeling complexes is now out @theplantjournal.bsky.social.
doi.org/10.1111/tpj....
Our work on PopP2 targeting core components of the PEAT chromatin-remodeling complexes is now out @theplantjournal.bsky.social.
doi.org/10.1111/tpj....
Brilliantly closing the @tulip-gs-labex.bsky.social Forum 2025 was @paduba.bsky.social (@lipme-toulouse.bsky.social) presenting her exploration of the core microbiota of photosynthetic organisms and upcoming projects as a CNRS permanent researcher 🤩
doi.org/10.1016/j.pb...
doi.org/10.1111/nph....
doi.org/10.1016/j.pb...
doi.org/10.1111/nph....
Building microbial synthetic communities: get inspired by the design of synthetic plant communities
In the last decade, the generation of host-associated microbial culture collections has allowed the fine disentangling of complex relationships between commensal microbes and their hosts, and within-...
doi.org
November 15, 2025 at 5:10 PM
Brilliantly closing the @tulip-gs-labex.bsky.social Forum 2025 was @paduba.bsky.social (@lipme-toulouse.bsky.social) presenting her exploration of the core microbiota of photosynthetic organisms and upcoming projects as a CNRS permanent researcher 🤩
doi.org/10.1016/j.pb...
doi.org/10.1111/nph....
doi.org/10.1016/j.pb...
doi.org/10.1111/nph....
PMD-C proteins-DNA motif modules antagonize Polycomb silencing to secure gene expression, Great work presented by Guillaume Moissiard (LGDP) at @tulip-gs-labex.bsky.social Forum 2025.
Check out the story about MAIN/MAIL1 and MAIL2, and M1M and M2M motifs !
👉 doi.org/10.1038/s414...
Check out the story about MAIN/MAIL1 and MAIL2, and M1M and M2M motifs !
👉 doi.org/10.1038/s414...
November 15, 2025 at 11:52 AM
PMD-C proteins-DNA motif modules antagonize Polycomb silencing to secure gene expression, Great work presented by Guillaume Moissiard (LGDP) at @tulip-gs-labex.bsky.social Forum 2025.
Check out the story about MAIN/MAIL1 and MAIL2, and M1M and M2M motifs !
👉 doi.org/10.1038/s414...
Check out the story about MAIN/MAIL1 and MAIL2, and M1M and M2M motifs !
👉 doi.org/10.1038/s414...
This morning, great start for the @tulip-gs-labex.bsky.social Forum 2025 with Takashi Ueda’s talk on VAMP727 neofunctionalization “Plant vacuolar transport rewired”
Check out the story & the super-resolution confocal imaging
👉 doi.org/10.1038/s414...
Check out the story & the super-resolution confocal imaging
👉 doi.org/10.1038/s414...
November 13, 2025 at 3:18 PM
This morning, great start for the @tulip-gs-labex.bsky.social Forum 2025 with Takashi Ueda’s talk on VAMP727 neofunctionalization “Plant vacuolar transport rewired”
Check out the story & the super-resolution confocal imaging
👉 doi.org/10.1038/s414...
Check out the story & the super-resolution confocal imaging
👉 doi.org/10.1038/s414...
Reposted by Léa Monge-Waleryszak
New pre-print from the team!
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
Primary metabolism underpins the execution of immune responses in different tissues of the same plant https://www.biorxiv.org/content/10.1101/2025.10.11.681807v1
October 14, 2025 at 7:16 AM
New pre-print from the team!
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
Reposted by Léa Monge-Waleryszak
New Article: "Vacuolar sorting receptors coordinate lytic vacuolar and autophagic transport for plant effector-triggered immunity" rdcu.be/eBbOG
VSRs orchestrate the vacuolar sorting of immune-related proteins and autophagic degradation of bacterial effectors in ETI.
VSRs orchestrate the vacuolar sorting of immune-related proteins and autophagic degradation of bacterial effectors in ETI.
August 18, 2025 at 10:51 AM
New Article: "Vacuolar sorting receptors coordinate lytic vacuolar and autophagic transport for plant effector-triggered immunity" rdcu.be/eBbOG
VSRs orchestrate the vacuolar sorting of immune-related proteins and autophagic degradation of bacterial effectors in ETI.
VSRs orchestrate the vacuolar sorting of immune-related proteins and autophagic degradation of bacterial effectors in ETI.
Reposted by Léa Monge-Waleryszak
📣 NEW PREPRINT 📝
We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...
cc @teamthomma.bsky.social
We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...
cc @teamthomma.bsky.social
Plant-associated fungi co-opt ancient antimicrobials for host manipulation
Evolutionary histories of effector proteins secreted by fungal pathogens to mediate plant colonization remain largely elusive. While most functionally characterized effectors modulate plant immunity, ...
www.biorxiv.org
August 15, 2025 at 7:47 AM
📣 NEW PREPRINT 📝
We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...
cc @teamthomma.bsky.social
We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...
cc @teamthomma.bsky.social
Reposted by Léa Monge-Waleryszak
New preprint: In situ Architecture of #Plasmodesmata.
Using #cryoET, #AlphaFold & proteomics, we uncover the native organization of plant intercellular nanopores.
🔗 doi.org/10.1101/2025...
🧪🧵1/n
#teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM
Using #cryoET, #AlphaFold & proteomics, we uncover the native organization of plant intercellular nanopores.
🔗 doi.org/10.1101/2025...
🧪🧵1/n
#teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM
July 26, 2025 at 3:38 PM
New preprint: In situ Architecture of #Plasmodesmata.
Using #cryoET, #AlphaFold & proteomics, we uncover the native organization of plant intercellular nanopores.
🔗 doi.org/10.1101/2025...
🧪🧵1/n
#teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM
Using #cryoET, #AlphaFold & proteomics, we uncover the native organization of plant intercellular nanopores.
🔗 doi.org/10.1101/2025...
🧪🧵1/n
#teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM
Reposted by Léa Monge-Waleryszak
How do chromatin remodelers use #IDRs to find TF binding partners? In our new Molecular Cell paper, we show that β-catenin is an adaptor that links SWI/SNF (cBAF) subunit ARID1A with binding partners via IDR-domain interactions.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
July 22, 2025 at 6:42 PM
How do chromatin remodelers use #IDRs to find TF binding partners? In our new Molecular Cell paper, we show that β-catenin is an adaptor that links SWI/SNF (cBAF) subunit ARID1A with binding partners via IDR-domain interactions.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Are chromatin remodelling complexes targets of bacterial effectors PopP2 & XopJ6 ? Check out our work at #2025ISMPMI ! P-163 presented Wednesday afternoon by my amazing PhD supervisors Laurent Deslandes & Valerie Pacquit. @lipme-toulouse.bsky.social @ismpmi.bsky.social
July 15, 2025 at 3:23 PM
Are chromatin remodelling complexes targets of bacterial effectors PopP2 & XopJ6 ? Check out our work at #2025ISMPMI ! P-163 presented Wednesday afternoon by my amazing PhD supervisors Laurent Deslandes & Valerie Pacquit. @lipme-toulouse.bsky.social @ismpmi.bsky.social
Reposted by Léa Monge-Waleryszak
Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants
Very happy to share the published version of our work on natural Marchantia-Pseudomonas interactions.
Out now in Current Biology: www.cell.com/current-biol...
Very happy to share the published version of our work on natural Marchantia-Pseudomonas interactions.
Out now in Current Biology: www.cell.com/current-biol...
Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants
Robinson et al. identify pathogenic Pseudomonas viridiflava in wild Marchantia polymorpha
liverworts and interrogate the mechanisms enabling virulence in non-flowering and
flowering plants. Their resu...
www.cell.com
April 1, 2025 at 7:12 PM
Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants
Very happy to share the published version of our work on natural Marchantia-Pseudomonas interactions.
Out now in Current Biology: www.cell.com/current-biol...
Very happy to share the published version of our work on natural Marchantia-Pseudomonas interactions.
Out now in Current Biology: www.cell.com/current-biol...
Love uncovering effector virulence strategies! 😀
Our work on PopP2 targeting core components of the PEAT chromatin-remodeling complexes is now out @theplantjournal.bsky.social.
doi.org/10.1111/tpj....
Our work on PopP2 targeting core components of the PEAT chromatin-remodeling complexes is now out @theplantjournal.bsky.social.
doi.org/10.1111/tpj....
Three ARID proteins involved in chromatin remodeling PEAT complexes are targeted by the Ralstonia solanacearum effector PopP2 and contribute to bacterial wilt disease
The Ralstonia solanacearum effector PopP2 is a YopJ family acetyltransferase. PopP2 is known to dampen basal immune responses by acetylating defensive WRKY transcription factors, and probably by targ...
doi.org
May 26, 2025 at 11:06 AM
Love uncovering effector virulence strategies! 😀
Our work on PopP2 targeting core components of the PEAT chromatin-remodeling complexes is now out @theplantjournal.bsky.social.
doi.org/10.1111/tpj....
Our work on PopP2 targeting core components of the PEAT chromatin-remodeling complexes is now out @theplantjournal.bsky.social.
doi.org/10.1111/tpj....
Reposted by Léa Monge-Waleryszak
Reposted by Léa Monge-Waleryszak
Very glad to see #HéloïseDemont PhD work online in @cp-cellreports.bsky.social! @lipme-toulouse.bsky.social #REACHteam
Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature: www.cell.com/cell-reports...
Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature: www.cell.com/cell-reports...
Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature
Demont et al. show that immune signaling induced by Toll/interleukin-1 receptor (TIR)
domains, including EDS1 and the SA sector, is maintained at elevated temperatures
(30°C), in contrast to signaling...
www.cell.com
March 3, 2025 at 3:10 PM
Very glad to see #HéloïseDemont PhD work online in @cp-cellreports.bsky.social! @lipme-toulouse.bsky.social #REACHteam
Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature: www.cell.com/cell-reports...
Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature: www.cell.com/cell-reports...
My PhD defense was an amazing moment. Many thanks to members of my jury for examining my work and for this very enjoyable discussion:
C. Segonzac
@ifudal.bsky.social
MH. Lebrun
B. Szurek
V. Cotelle
Huge thanks to my increadible supervisors L. Deslandes & V. Pacquit for their unfailing support.
C. Segonzac
@ifudal.bsky.social
MH. Lebrun
B. Szurek
V. Cotelle
Huge thanks to my increadible supervisors L. Deslandes & V. Pacquit for their unfailing support.
February 2, 2025 at 4:16 PM
My PhD defense was an amazing moment. Many thanks to members of my jury for examining my work and for this very enjoyable discussion:
C. Segonzac
@ifudal.bsky.social
MH. Lebrun
B. Szurek
V. Cotelle
Huge thanks to my increadible supervisors L. Deslandes & V. Pacquit for their unfailing support.
C. Segonzac
@ifudal.bsky.social
MH. Lebrun
B. Szurek
V. Cotelle
Huge thanks to my increadible supervisors L. Deslandes & V. Pacquit for their unfailing support.
Reposted by Léa Monge-Waleryszak
[#PhD] 👩🎓 Today Léa Monge Waleryszak defends his PhD on "Investigating the proximal proteomes of 2 YopJ family acetyltrasferases from 2 plant vascular pathogenic bacteria"
@ifudal.bsky.social
@ifudal.bsky.social
January 31, 2025 at 12:37 PM
[#PhD] 👩🎓 Today Léa Monge Waleryszak defends his PhD on "Investigating the proximal proteomes of 2 YopJ family acetyltrasferases from 2 plant vascular pathogenic bacteria"
@ifudal.bsky.social
@ifudal.bsky.social