lindnerlab.bsky.social
@lindnerlab.bsky.social
Lipid nanoparticles for retinal gene delivery - Read out latest preprint at biorxiv.org/content/10.1101/2025.11.21.689792v1 !
LNPs are able to transfect a variety of retinal cell types - including NEURONS! Previous ILM peeling improves efficacy!
#retina #GeneTherapy #LNP @unimarburg.bsky.social
November 24, 2025 at 11:42 AM
ERGtools2 — an #OpenSource R package for analyzing and managing visual electrophysiology data ( #ERG / #VEP ).
Device-independent, reproducible, FAIR-compliant & ready for preclinical and clinical research.
Paper: doi.org/10.1007/s106...
Code: github.com/moritzlindne...
@unimarburg.bsky.social
The ERGtools2 package: a toolset for processing and analysing visual electrophysiology data - Documenta Ophthalmologica
Purpose To introduce ERGtools2, an open-source R package for processing, analysing and long-term storing visual electrophysiology data. Methods A dataset comprising Electroretinogram (ERG) recordings ...
doi.org
June 11, 2025 at 9:35 AM
New perspectives on #optogenetic #VisionRestoration
In my letter in @moltherapy.bsky.social‬, I comment on recent clinical data on vMCO-010 and highlight the need for mechanistic insight & objective efficacy measures.
Many open questions remain - exciting times ahead! @unimarburg.bsky.social #Retina
June 11, 2025 at 9:28 AM
Optogenetic Therapy in patients with residual visual function?
In this study, we show that optogenetic responses complexly interact with native visual processing. doi.org/10.1172/jci.... @unimarburg.bsky.social @ox.ac.uk @jci-insight.bsky.social#Optogenetics #Neuroscience #Retina #GeneTherapy
June 6, 2025 at 7:46 AM