Lignani Lab
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lignanilab.bsky.social
Lignani Lab
@lignanilab.bsky.social
UCL/ Neuroscience/ Epilepsy/ Gene therapy/ Brain Dynamics/ Dravet Syndrome/ CRISPR/ Homeostatic plasticity
Reposted by Lignani Lab
Did you know that people with #epilepsy have a significantly reduced life expectancy and an increased burden of age-related comorbidities? Our new study „Time flies faster in epilepsy“ lnkd.in/d28QCtMS looks into how biological aging contributes to the disease.
October 9, 2025 at 5:50 AM
Reposted by Lignani Lab
Today is #WorldBrainDay, a global campaign promoting brain health for all ages.
At UCL, we're spotlighting some of the groundbreaking research that's shaping the future of brain health and wellbeing. 🧵
July 22, 2025 at 10:08 AM
Reposted by Lignani Lab
2/ Prof Gabriele Lignani of @lignanilab.bsky.social is leading an international team of researchers to develop a new generation of cell-state gene therapies for neuropsychiatric disorders.

www.ucl.ac.uk/brain-scienc...
Professor Gabriele Lignani on developing new gene therapies for neuropsychiatric disorders
Professor Gabriele Lignani is leading an international team of researchers to develop a new generation of cell-state gene therapies for neuropsychiatric disorders
www.ucl.ac.uk
July 22, 2025 at 10:08 AM
Reposted by Lignani Lab
Very excited to share my (first 😁) first-author preprint from my PhD work with @lignanilab.bsky.social 🎉
We uncovered an unexpected role for Nav1.1 in early cortical development, notably in the regulation of the cell cycle in cortical progenitors.
www.researchsquare.com/article/rs-6...
Prenatal sodium channel dysfunction in Dravet syndrome alters cortical development
Neurodevelopmental disorders associated with epilepsy are typically linked to postnatal dysfunction of synaptic proteins and ion channels, yet increasing evidence suggests a role for these proteins be...
www.researchsquare.com
May 16, 2025 at 5:28 PM
Thrilled to share that our latest work on #DravetSyndrome is now out as a preprint! 🚀
This project, brilliantly led by @clarazourray.bsky.social and co-supervised by Serena Barral, brought together an incredible team.
A huge thanks to everyone involved, exciting science ahead! 👏
shorturl.at/NdC79
Prenatal sodium channel dysfunction in Dravet syndrome alters cortical development
Neurodevelopmental disorders associated with epilepsy are typically linked to postnatal dysfunction of synaptic proteins and ion channels, yet increasing evidence suggests a role for these proteins be...
www.researchsquare.com
May 16, 2025 at 4:59 PM
Reposted by Lignani Lab
UCL researchers will receive £8.1m in @aria-research.bsky.social funding to embark on cutting edge research to help overcome neurodegenerative diseases.
@uclpals.bsky.social @uclqsion.bsky.social
bit.ly/4g9MN1H
UCL researchers receive £8.1 million ARIA funding for innovative brain research
UCL researchers will receive £8.1m in funding to embark on cutting edge research to help overcome neurodegenerative diseases.
bit.ly
January 21, 2025 at 2:58 PM
Thrilled to announce that our international team has been awarded a prestigious research grant! Together, we aim to tackle some of the most complex neurological diseases using cutting-edge technologies. Excited for the journey ahead! @aria-research.bsky.social @ucl.ac.uk @uclqsion.bsky.social
We’re excited to announce the 18 teams we’re funding in Precision Neurotechnologies 🧠 They’ll work to unlock new ways to interface with the brain at the neural circuit level, with unprecedented precision. (1/3)
January 20, 2025 at 2:26 PM
Deadline extend to 19th January!
📢 We are looking for a dynamic, energetic and passionate postdoc fellow to work on in vivo electrophysiology to understand and treat neurological diseases! Deadline 8th January #neuropixels #braindynamics #epilepsy #neurodiseases

tinyurl.com/5n6sad38
January 6, 2025 at 6:28 PM
Reposted by Lignani Lab
We're hiring! 🧠 We're looking for a postdoc to perform neuropixels recordings in mouse models of neurological disorders as part of a larger team that's testing out novel gene therapies here at UCL. Super exciting project, come join the team! tinyurl.com/2ykfy2um
#neuroskyence
#neurojobs
December 20, 2024 at 1:58 PM
📢 We are looking for a dynamic, energetic and passionate postdoc fellow to work on in vivo electrophysiology to understand and treat neurological diseases! Deadline 8th January #neuropixels #braindynamics #epilepsy #neurodiseases

tinyurl.com/5n6sad38
December 24, 2024 at 1:44 PM