Laura Chacon Machado
laurachaconmachado.bsky.social
Laura Chacon Machado
@laurachaconmachado.bsky.social
PhD candidate at Joe Peters Lab, Cornell Microbiology. Interested in mobile genetic elements, particularly Tn7-like transposons.
Reposted by Laura Chacon Machado
Feels awkward but necessary to celebrate scientific progress in this imperiled time for US biomedical research.

Proud of our latest paper out today exploring the role of transposable elements in antiviral resistance to HIV 🦠

genomebiology.biomedcentral.com/articles/10....
🧵1/n
Transposable elements may enhance antiviral resistance in HIV-1 elite controllers - Genome Biology
Background Less than 0.5% of people living with HIV-1 are elite controllers (ECs)—individuals who maintain undetectable plasma viremia without antiretroviral therapy, despite having replication-compet...
genomebiology.biomedcentral.com
February 24, 2025 at 12:27 PM
Our preprint describing a family of Tn7-like transposons that evolved to target CRISPR repeats is now published at Mobile DNA #Tn7 #transposons #mobileDNA 1/10
mobilednajournal.biomedcentral.com/articles/10....
A family of Tn7-like transposons evolved to target CRISPR repeats - Mobile DNA
Tn7 family transposons are mobile genetic elements known for precise target site selection, with some co-opting CRISPR-Cas systems for RNA-guided transposition. We identified a novel group of Tn7-like...
mobilednajournal.biomedcentral.com
February 18, 2025 at 9:18 PM