Helen Rowe @RoweLab
banner
labrowe.bsky.social
Helen Rowe @RoweLab
@labrowe.bsky.social
Discovery science driven. Hope to contribute to translating discoveries into new medicines.
How do pluripotent stem cells resist harmful interferon responses to safeguard development? Through total epigenetic lockdown of ligands, sensors and effectors of IFN-I. In our preprint, James Holt shares his PhD discoveries on the ground state of immune evasion 😊: www.biorxiv.org/cgi/content/...
Epigenetic lockdown of type I interferon sensing and signalling in human pluripotent cells.
The Human Silencing Hub (HUSH) complex safeguards genome integrity in human somatic cells by repressing transposable elements and regulating type I interferon (IFN-I) induction. In early development, ...
www.biorxiv.org
October 29, 2025 at 6:03 PM
What's on the horizon of cancer immunotherapies? Understanding epigenetic checkpoints, we say 😊: news.cancerresearchuk.org/2025/09/11/l...
Level-up: Looking to epigenetics for the next immunotherapy breakthrough - Cancer Research UK - Cancer News
Checkpoint inhibitors have utterly changed the immunotherapy landscape – but there could be a different kind of checkpoint just waiting to be targeted...
news.cancerresearchuk.org
September 11, 2025 at 1:28 PM
Looking forward to this meeting this week: Transposable elements are controlling elements in health and disease, genetics.org.uk/events/the-r... organised by the Genetics Society 😊
The real point is control: transposons as controlling elements in evolution, development and disease | Genetics Society
This three-day conference will run from Wednesday 20th to Friday 22nd November 2024 in Leicester. Background: When Barbara McClintock first described transposable elements in the 1940s, the scientif...
genetics.org.uk
November 19, 2024 at 9:18 AM
Reposted by Helen Rowe @RoweLab
Please register for the course on Transposable elements in #genomics and #datascience. We will be sharing the magic of #nanopore long reads for #transposon expression #tesky
November 19, 2024 at 8:15 AM
I’m happy to announce that I’ve been promoted to Professor! 🥳 I’m so grateful to everyone who has supported me, to my amazing lab members and to all who have made my scientific journey fun along the way ☀️. Thank you Queen Mary University!
August 29, 2024 at 2:36 PM
I am thrilled and incredibly proud that recent PhD student @Liane Fernandes from my lab @QMUL has won a prestigious EMBO Fellowship! Exciting science ahead ❤️ 🏆
June 19, 2024 at 9:42 AM
How do tumours evade destruction by the immune system? We are recruiting two postdocs (wet lab/dry lab) to shed light on epigenetic checkpoints of anti-tumour immunity in lung cancers, funded by CRUK. Please get in touch to find out more!
www.qmul.ac.uk/jobs/vacanci...
www.qmul.ac.uk/jobs/vacanci...
March 18, 2024 at 7:16 PM
I am honoured to receive a Programme Foundation Award from Cancer Research UK on epigenetic regulation of immune evasion in non-small cell lung cancer. Thanks to my co-investigators, collaborators, mentors, lab & @qmulepigenetics.bsky.social for supporting this exciting translational project.
February 2, 2024 at 9:27 AM
Reposted by Helen Rowe @RoweLab
Please join us for the @QMULepigenetics seminar by Kristian Helin from @icr_london 11th Jan. 15.30GMT. venue: Derek Willoughby Lecture Theatre, at our Charterhouse Square campus. or online link at qmulepigenetics.com/webinars
January 11, 2024 at 1:59 AM
Reposted by Helen Rowe @RoweLab
Dear TE family, it is time! The early-bird registration ends January 15th already! Abstract for talks ends February 15th! Start procrastinating by doing something useful: register to #icte2024 ! See you soon! #transposon
December 18, 2023 at 11:02 AM
Enlightening review from @KathleenHBurns lab: genesdev.cshlp.org/content/37/2...: LINE-1 activity and jumping contributes to genetic instability in cancer and understanding LINE-1 deregulation could lead to new therapeutic opportunities. A must-read.
January 3, 2024 at 6:02 PM
Elegant preprint identifying mutually exclusive targeting of HUSH1 vs. HUSH2 chromatin complexes for silencing dangerous LINE-1 elements in the human genome: www.biorxiv.org/content/10.1...
December 30, 2023 at 1:52 PM