Kent Søe
kentsoe.bsky.social
Kent Søe
@kentsoe.bsky.social
Strong interest for #bone #research and #osteoclast in the context of #osteoporosis, #breastcancer, and #prostatecancer. @SDU.DK @OUHhospital @SUND_SDU
New paper out in JBMRPlus !
Using a time-lapse co-culture approach with #osteoclasts and reversal cells, we show that reversal cells prefer pits over trenches, but that intermediate #CatK inhibition boosts their attraction and maturation into #osteoblasts.
track.smtpsendmail.com/9032119/c?p=...
Cathepsin K inhibitors promote osteoclast-osteoblast communication and engagement of osteogenesis
Abstract. Cathepsin K inhibitors are well known for their inhibitory activity against bone resorption but were also reported to preserve bone formation in
track.smtpsendmail.com
August 4, 2025 at 9:16 AM
Do we make the best of the synergistic potential between basic and clinical scientists? This is the topic we as members of the Basic and Clincal Science Action Groups of @ectssociety.bsky.social (ECTS) and ECTS Academy discuss in this paper!
rdcu.be/d9WxL
@asbmr.bsky.social @ifmrs.bsky.social
Basic and Clinical Scientists Working Together—Do We Make the Best of Both Worlds?
rdcu.be
February 16, 2025 at 12:03 PM
If you are interested in the impact of long non-coding RNA and uRNA on #human #osteoclast differentiation and #bone resorption, you may be interested in our paper published late last year - Open Access
www.nature.com/articles/s41...
Stage-specific modulation of multinucleation, fusion, and resorption by the long non-coding RNA DLEU1 and miR-16 in human primary osteoclasts - Cell Death & Disease
Cell Death & Disease - Stage-specific modulation of multinucleation, fusion, and resorption by the long non-coding RNA DLEU1 and miR-16 in human primary osteoclasts
www.nature.com
January 26, 2025 at 2:27 PM