Dan Kelpsch
@kelpschd.bsky.social
Postdoc in Steve Farber's lab at JHU
🏳️🌈
🏳️🌈
Reposted by Dan Kelpsch
We investigated triglyceride synthesis enzymes in the zebrafish. Counterintuitively, loss of Dgat2 activity leads to abnormal accumulation of lipid droplets in larvae, and we were amazed to find that dgat1a;dgat1b;dgat2 triple mutant fish are viable and healthy! doi.org/10.1016/j.jb...
December 4, 2024 at 8:53 PM
We investigated triglyceride synthesis enzymes in the zebrafish. Counterintuitively, loss of Dgat2 activity leads to abnormal accumulation of lipid droplets in larvae, and we were amazed to find that dgat1a;dgat1b;dgat2 triple mutant fish are viable and healthy! doi.org/10.1016/j.jb...
I'm thrilled to share my work summarizing a drug screen in whole animals to identify new lipoprotein-reducing drugs!
#zebrafish #cholesterol #CVD
#zebrafish #cholesterol #CVD
A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins. https://www.biorxiv.org/content/10.1101/2024.11.14.623618v1
A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins. https://www.biorxiv.org/content/10.1101/2024.11.14.623618v1
Lipoproteins are essential for lipid transport in all bilaterians. A single Apolipoprotein B (ApoB)
www.biorxiv.org
November 16, 2024 at 4:03 AM
I'm thrilled to share my work summarizing a drug screen in whole animals to identify new lipoprotein-reducing drugs!
#zebrafish #cholesterol #CVD
#zebrafish #cholesterol #CVD