Christian Diwo
@kartoffelchris.bsky.social
Engineer & Scientist | Inventing Solutions to Measure the Unknown | GIMM & CBR Lisbon | Wer das liest, kann Deutsch lesen
Reposted by Christian Diwo
I’ve begun my journey to reduce my reliance on US tech, so it’s time for an update on how it’s all going!
No surprise, some services are far more easy to replace than others. Email and streaming are low-hanging fruit; maps and messaging can be more difficult. But we should still make the effort.
No surprise, some services are far more easy to replace than others. Email and streaming are low-hanging fruit; maps and messaging can be more difficult. But we should still make the effort.
Getting off US tech is no easy task
But that doesn’t mean we shouldn’t make the effort
www.disconnect.blog
June 23, 2025 at 1:06 PM
I’ve begun my journey to reduce my reliance on US tech, so it’s time for an update on how it’s all going!
No surprise, some services are far more easy to replace than others. Email and streaming are low-hanging fruit; maps and messaging can be more difficult. But we should still make the effort.
No surprise, some services are far more easy to replace than others. Email and streaming are low-hanging fruit; maps and messaging can be more difficult. But we should still make the effort.
Reposted by Christian Diwo
Better late than never, but I am thrilled to share our newest research from the Treeck lab!!! www.nature.com/articles/s41...
The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound - Nature Microbiology
FIKK effector kinases underwent rapid evolutionary expansion and are a druggable target in Plasmodium falciparum.
www.nature.com
June 23, 2025 at 1:28 PM
Better late than never, but I am thrilled to share our newest research from the Treeck lab!!! www.nature.com/articles/s41...
Reposted by Christian Diwo
New lab preprint - Delora Baptista tested AlphaFold 2 and 3 for the prediction of structures of host-pathogen interactions and then applied these to study convergence of binding and molecular mimicry in host-pathogen vs. host-host interactions.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
AlphaFold models of host-pathogen interactions elucidate the prevalence and structural modes of molecular mimicry
Pathogens exploit host cellular machinery through protein-protein interactions (PPIs), often using molecular mimicry to hijack host cellular processes. While there have been thousands of host-pathogen...
www.biorxiv.org
June 9, 2025 at 6:58 AM
New lab preprint - Delora Baptista tested AlphaFold 2 and 3 for the prediction of structures of host-pathogen interactions and then applied these to study convergence of binding and molecular mimicry in host-pathogen vs. host-host interactions.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Inserting membrane proteins into the ER is complex and error prone. We use an unconventional viral proton channel as a model to find out about redundancy and buffering mechanisms in human membrane protein biogenesis.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Functional redundancy in Oxa1-family insertases supports robust membrane insertion of influenza A virus M2 viroporin
The biogenesis of thousands of highly diverse membrane proteins in humans is facilitated by an array of ER-resident membrane protein translocases. While some membrane proteins have a strict requiremen...
doi.org
June 6, 2025 at 12:05 PM
Inserting membrane proteins into the ER is complex and error prone. We use an unconventional viral proton channel as a model to find out about redundancy and buffering mechanisms in human membrane protein biogenesis.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
doi.org/10.1101/2025...
doi.org/10.1101/2025...