Karthee Madasamy
@kartheemadasamy.bsky.social
Early stage deep tech VC @ MFV Partners
Elon's glitch is the funniest thing of this year's SNL! and Mike Myers killing it!
April 6, 2025 at 4:59 AM
Elon's glitch is the funniest thing of this year's SNL! and Mike Myers killing it!
Gotta say, Substack has become what Medium set out to be.
I am discovering a lot more insightful long form content in Substack.
I am discovering a lot more insightful long form content in Substack.
March 30, 2025 at 8:25 PM
Gotta say, Substack has become what Medium set out to be.
I am discovering a lot more insightful long form content in Substack.
I am discovering a lot more insightful long form content in Substack.
AOC, Pete Buttigieg, Chris Murphy - who else is articulating the issues and offering alternatives ?
March 3, 2025 at 11:09 PM
AOC, Pete Buttigieg, Chris Murphy - who else is articulating the issues and offering alternatives ?
Real negotiators show toughness to all sides—not just bullying allies while going soft on dictators.
February 28, 2025 at 6:45 PM
Real negotiators show toughness to all sides—not just bullying allies while going soft on dictators.
Reposted by Karthee Madasamy
Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic.
globalnews.ca/news/9793403...
globalnews.ca/news/9793403...
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
globalnews.ca
February 9, 2025 at 5:38 PM
Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic.
globalnews.ca/news/9793403...
globalnews.ca/news/9793403...
Reposted by Karthee Madasamy
Complete hardware + software setup for running Deepseek-R1 locally. The actual model, no distillations, and Q8 quantization for full quality. Total cost, $6,000. All download and part links below:
January 28, 2025 at 2:40 PM
Complete hardware + software setup for running Deepseek-R1 locally. The actual model, no distillations, and Q8 quantization for full quality. Total cost, $6,000. All download and part links below:
Deep Research from OpenAI is a game changer!
February 7, 2025 at 9:22 AM
Deep Research from OpenAI is a game changer!
Anyone discussing Deepseek here?
Here is a good explainer video on the breakthrough -
youtu.be/DCqqCLlsIBU?...
Here is a good explainer video on the breakthrough -
youtu.be/DCqqCLlsIBU?...
DeepSeek-R1 Paper Explained - A New RL LLMs Era in AI?
YouTube video by AI Papers Academy
youtu.be
January 27, 2025 at 6:31 PM
Anyone discussing Deepseek here?
Here is a good explainer video on the breakthrough -
youtu.be/DCqqCLlsIBU?...
Here is a good explainer video on the breakthrough -
youtu.be/DCqqCLlsIBU?...
I just hope the Dems don’t become an Anti-Tech party after seeing Bezos, Musk and Zuck bend the knee.
That would be the wrong lesson!
That would be the wrong lesson!
January 22, 2025 at 5:29 AM
I just hope the Dems don’t become an Anti-Tech party after seeing Bezos, Musk and Zuck bend the knee.
That would be the wrong lesson!
That would be the wrong lesson!
Indian American tech bros learning on the fly that GOP is as much about Laura Loomer, Ashley St Clair, and Ann Coulter as it about Elon Musk!
December 25, 2024 at 9:01 PM
Indian American tech bros learning on the fly that GOP is as much about Laura Loomer, Ashley St Clair, and Ann Coulter as it about Elon Musk!
Gotta say these two skits of Washington's Dreams by Nate Bargatze have been my recent SNL favorites. Classic!
www.youtube.com/watch?v=JYqf...
www.youtube.com/watch?v=VJ62...
www.youtube.com/watch?v=JYqf...
www.youtube.com/watch?v=VJ62...
Washington's Dream - SNL
YouTube video by Saturday Night Live
www.youtube.com
December 22, 2024 at 6:27 AM
Gotta say these two skits of Washington's Dreams by Nate Bargatze have been my recent SNL favorites. Classic!
www.youtube.com/watch?v=JYqf...
www.youtube.com/watch?v=VJ62...
www.youtube.com/watch?v=JYqf...
www.youtube.com/watch?v=VJ62...
Boy, how many such stories do we have of cricketers in India? For all the people ranting about cricket's decline in India, the IPL and the money in cricket have unlocked so much talent and fulfilled many dreams!
www.smh.com.au/sport/cricke...
www.smh.com.au/sport/cricke...
‘Cricket was a crime’: Beating odds nothing new for India’s follow-on hero Akash Deep
Growing up in one of India’s poorest regions, parents told their kids to study and not hang around with Akash Deep because he was a bad influence. Deep dreamed of becoming a professional cricketer ins...
www.smh.com.au
December 22, 2024 at 3:18 AM
Boy, how many such stories do we have of cricketers in India? For all the people ranting about cricket's decline in India, the IPL and the money in cricket have unlocked so much talent and fulfilled many dreams!
www.smh.com.au/sport/cricke...
www.smh.com.au/sport/cricke...
Reposted by Karthee Madasamy
Who leads the global renewable energy race? Europe has the highest share of wind and solar in electricity generation but China by far has most capacity installed.
Source is RMI
Source is RMI
December 15, 2024 at 11:17 AM
Who leads the global renewable energy race? Europe has the highest share of wind and solar in electricity generation but China by far has most capacity installed.
Source is RMI
Source is RMI
Indian Cricket is squandering the peak form of World's #1 bowler, a generational talent, by insipid selection of T20 and over-the-hill players into the test team. What a waste!
December 9, 2024 at 3:15 PM
Indian Cricket is squandering the peak form of World's #1 bowler, a generational talent, by insipid selection of T20 and over-the-hill players into the test team. What a waste!
Reposted by Karthee Madasamy
Lots of new AI people on Bluesky today! I updated my highly-opinionated starter pack of who to follow: go.bsky.app/V62wBer
November 18, 2024 at 10:27 PM
Lots of new AI people on Bluesky today! I updated my highly-opinionated starter pack of who to follow: go.bsky.app/V62wBer
Go Blue! 4th win in a row for @UMichFootball over @OhioStateFB !
Since that infamous “Hang 100 on Michigan” comment from OSU coach, they haven’t beaten Michigan!
Karma!
Since that infamous “Hang 100 on Michigan” comment from OSU coach, they haven’t beaten Michigan!
Karma!
November 30, 2024 at 9:10 PM
Go Blue! 4th win in a row for @UMichFootball over @OhioStateFB !
Since that infamous “Hang 100 on Michigan” comment from OSU coach, they haven’t beaten Michigan!
Karma!
Since that infamous “Hang 100 on Michigan” comment from OSU coach, they haven’t beaten Michigan!
Karma!
What movie(s) do you end up watching every year ?
For me -
Godfather Trilogy
Austin Powers trilogy
😂
For me -
Godfather Trilogy
Austin Powers trilogy
😂
November 29, 2024 at 3:46 AM
What movie(s) do you end up watching every year ?
For me -
Godfather Trilogy
Austin Powers trilogy
😂
For me -
Godfather Trilogy
Austin Powers trilogy
😂
Thankful and grateful for health, friends, family and the opportunities!
Happy Thanksgiving everyone!
Happy Thanksgiving everyone!
November 28, 2024 at 9:11 PM
Thankful and grateful for health, friends, family and the opportunities!
Happy Thanksgiving everyone!
Happy Thanksgiving everyone!
From PsiQuantum - resource-optimized fault-tolerant implementations of Fermi-Hubbard.
This is a major milestone for useful Quantum Computing!
arxiv.org/abs/2411.02160
This is a major milestone for useful Quantum Computing!
arxiv.org/abs/2411.02160
Resource-optimized fault-tolerant simulation of the Fermi-Hubbard model and high-temperature superconductor models
Exploring low-cost applications is paramount to creating value in early fault-tolerant quantum computers. Here we optimize both gate and qubit counts of recent algorithms for simulating the Fermi-Hubb...
arxiv.org
November 27, 2024 at 8:43 PM
From PsiQuantum - resource-optimized fault-tolerant implementations of Fermi-Hubbard.
This is a major milestone for useful Quantum Computing!
arxiv.org/abs/2411.02160
This is a major milestone for useful Quantum Computing!
arxiv.org/abs/2411.02160
Moore’s Law has reached its limit. Quantum computing is the only technology poised to unlock the next era of computing power.
November 27, 2024 at 8:39 PM
Moore’s Law has reached its limit. Quantum computing is the only technology poised to unlock the next era of computing power.
How do we define a deep tech startup?
- Proprietary technology
- that's hard to replicate providing a strong moat
- which provides the raison d'être for the startup's existence
- Proprietary technology
- that's hard to replicate providing a strong moat
- which provides the raison d'être for the startup's existence
November 27, 2024 at 5:10 AM
How do we define a deep tech startup?
- Proprietary technology
- that's hard to replicate providing a strong moat
- which provides the raison d'être for the startup's existence
- Proprietary technology
- that's hard to replicate providing a strong moat
- which provides the raison d'être for the startup's existence
It looks like everyone is hopeful that the IPO market opens up in 2025! So many in the queue!
November 26, 2024 at 9:33 PM
It looks like everyone is hopeful that the IPO market opens up in 2025! So many in the queue!
Focus on fundamentals! And focus on technologies that drive business value! My article on climate tech for the Trump era!
fortune.com/2024/11/25/t...
fortune.com/2024/11/25/t...
Trump’s plans to kill EV subsidies signal a new era of climate tech Darwinism
'For investors like me, this means looking at the market through a new lens,' writes MFV Partners founder Karthee Madasamy.
fortune.com
November 25, 2024 at 5:09 PM
Focus on fundamentals! And focus on technologies that drive business value! My article on climate tech for the Trump era!
fortune.com/2024/11/25/t...
fortune.com/2024/11/25/t...