Jonathan Slaughter MD
jslaughtermd.bsky.social
Jonathan Slaughter MD
@jslaughtermd.bsky.social
Father, Neonatologist, Epidemiologist- working to improve neonatal outcomes #comparativeeffectiveness #pharmacoepidemiology #Neosky
Reposted by Jonathan Slaughter MD
Preterm cooling trial published, previously presented at PAS 2023.

No difference in primary outcome. Bayesian analysis suggests 87% probability of increased risk of death with hypothermia. Practice changing for those who are cooling this population?

#neobluesky

jamanetwork.com/journals/jam...
Whole-Body Hypothermia for Neonatal Encephalopathy
This randomized clinical trial investigates if hypothermia initiated at less than 6 hours after birth reduces the probability of death or disability at 18 to 22 months’ corrected age in infants 33 to ...
jamanetwork.com
February 24, 2025 at 9:03 PM
Reposted by Jonathan Slaughter MD
I guess it's not surprising that our organizations and journals must lag a bit in adoption of a new platform, but they are an important part of the conversation. Let's encourage whatever we're affiliated with to take the leap. We can log them here (currently pretty sparse)

go.bsky.app/DwfZqQF
November 20, 2024 at 12:22 AM
Reposted by Jonathan Slaughter MD
Updated meta-regression by Prof Lex Doyle et al. in JAMA Pediatrics examines how potential benefit from Dexamethasone and Hydrocortisone changes with baseline risk of BPD among included trials. #neoEBM #neosky #EBNEOalerts
buff.ly/3CNa6Ae
November 21, 2024 at 1:34 PM
Reposted by Jonathan Slaughter MD
Important article on Dexamethasone: Doyle LW, Mainzer R, Cheong JLY. Systemic Postnatal Corticosteroids, Bronchopulmonary Dysplasia, and Survival Free of Cerebral Palsy. JAMA Pediatr. Published online November 18, 2024. doi:10.1001/jamapediatrics.2024.4575

jamanetwork.com/journals/jam...
November 18, 2024 at 8:28 PM
Reposted by Jonathan Slaughter MD
Time to regroup and like a phoenix, rising from the ashes, reunite here where the skies are so beautifully blue
go.bsky.app/5GFC5VL
#NeoSky
November 16, 2024 at 2:22 AM
Reposted by Jonathan Slaughter MD
A friendly reminder to #NeoSky on a pet topic:
PPIs have very little evidence of benefit in neonates and potential for harm.
We did a systematic review of acid suppression after TOF/OA (EA/TEF) repair and found no benefit: www.sciencedirect.com/science/arti...
Prophylactic Acid-suppression Medication to Prevent Anastomotic Strictures After Oesophageal Atresia Surgery: A Systematic Review and Meta-analysis
Anastomotic stricture is a common postoperative complication of oesophageal atresia ± tracheoesophageal fistula (OA/TOF) repair. Acid gastro-oesophage…
www.sciencedirect.com
November 15, 2024 at 1:20 PM
Reposted by Jonathan Slaughter MD
To start things off - we'll share a couple of our recent #ebneoalerts.

Results of the PLUSS trial led by @drbretty.bsky.social published in JAMA.

Paper: buff.ly/48Kmhtz
Editorial: buff.ly/40HxadL

#neoEBM #EBNEOAlerts #neoSky
November 16, 2024 at 12:12 AM