One strength of the Dormanns et al model is how it isolates the temporal roles of neuronal vs endothelial NO and their interactions with other signals like K⁺. It gives a structured way to test how different sources of NO contribute to CBF dynamics, something hard to dissect in vivo.
#Neuroskyence

Wake up moment!!! 🎥✨
#Astrocyte calcium bursts light up as the brain shifts from sleep to wakefulness in postnatal mice. 👉 Pay attention to the glowing #vasculature. ⚡
#NeonatalBrain #NeurovascularCoupling #liveimaging @ucoimbra.bsky.social @lacaixa.bsky.social

The model of NO in neurovascular coupling by Dormanns and colleagues offers a valuable lens into how timing, cellular sources, and feedback loops shape flow responses. Although it isn't a mirror of in vivo reality this seems a strong base for hypothesis-building in hippocampal NVC.
shorturl.at/CuBss

The 2nd FEBS Workshop on Redox Medicine is here!
Explore how the exposome influences #Redox regulation in health & disease.
It's a unique chance for PhD students & postdocs to connect with top experts!

When? 6-9 Oct 2025
Where? Portugal

More info at redoxmedicine2025.febsevents.org

Are you using the right methods for your #nitricoxide work?

Check out our special issue @nioxjournal.bsky.social edited by our Editor in chief Sruti Shiva @sshiva.bsky.social and Douglas Thomas dedicated to techniques in Nitric Oxide research

Interestingly, the positive effects of nitrate appear to be linked to the duration of supplementation, instead of following a dose-dependent pattern!

#neurovascular #nitricoxide #neuroskyence #cognition

portlandpress.com/biochemsoctr...

Time to recap one of our recent publications!

Here we reviewed evidence linking dietary nitrate supplementation, cognition, and neurovascular health.

Curious to hear your thoughts on nutraceuticals, cognition, and cerebral NO signaling 😊

This study reveals disrupted nitric oxide-dependent NVC in the hippocampus of young GK rats (T2DM animal model).
T2DM was also associated with poor spatial memory and learning
#neuroskyence

Some of our work: "Impairment of neurovascular coupling in the hippocampus due to decreased nitric oxide bioavailability supports early cognitive dysfunction in type 2 diabetic rats"

#neurovascular #cognition
#nitricoxide #diabetes

www.sciencedirect.com/science/arti...

Hi everyone!

I currently work on nitric oxide-dependent neurovascular coupling and cognition.
Would also love to explore intersections between Neuroscience and computational methods!

If you're into #neurovascular research, #cognition, #Redox biology, or #computational Neuroscience, let's chat!