jhxinglab.bsky.social
@jhxinglab.bsky.social
Despite great progress in image analyses, analyzing live-cell images remains highly challenging, which requires further improvement of the already state-of-the-art algorithms such as Cellpose developed for snapshot images.
Check out our preprint: www.biorxiv.org/content/10.1...
LivecellX: Corrective Deep Learning for Object-Oriented Single-Cell Analysis in Live-Cell Imaging
Live cell imaging uniquely captures single-cell dynamics in space and time, but robust analysis is limited by segmentation and tracking errors that accumulate across frames. We present LivecellX, a de...
www.biorxiv.org
December 3, 2025 at 11:32 PM
Analyses on Hi-C and MERFISH chromosome tracing data and live-cell imaging revealed stable structures formed by long-range intrachromosome loci, potentially guiding chromosome folding into segregated territories
www.biorxiv.org/content/10.1...
Long-range genomic loci stochastically assemble into combinatorial forms of chromosome skeleton
One fundamental yet open question is how eukaryotic chromosomes fold into segregated territories, a process essential for gene transcription and cell fate. Through analyzing Hi-C and chromatin-tracing...
www.biorxiv.org
February 12, 2025 at 1:05 PM