Journal of Cardiac Failure
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jcardfail.bsky.social
Journal of Cardiac Failure
@jcardfail.bsky.social
The official journal of @hfsa.bsky.social for original peer-reviewed research & reviews.

Co-EIC:
@robmentz.bsky.social &
@dranulala.bsky.social

https://linktr.ee/jcardfail
A New Year brings new insights.

The January issue of JCF is here, highlighting timely research and emerging conversations shaping the year ahead in heart failure science.

Start reading 📖 https://onlinejcf.com/current

#HeartFailure #Cardiology
January 15, 2026 at 6:37 PM
New science 🚨! In the BRING-UP-3 HF study, among ambulatory HF pts in Italy, 65% of HFrEF pt received all 4 GDMT pillars. BBs & RASi/ARNI >90%, MRAs & SGLT2i >80% (though target doses still low). SGLT2i already common in HFmrEF (72%) & HFpEF (50%)!

🔗 https://bit.ly/44jVymK
January 15, 2026 at 4:48 PM
Despite strong evidence, GDMT remains underused. In this Indian expert consensus doc, using a modified Delphi process, authors propose simplified, patient-profile–based guidance to enable early, safe initiation of the 4 GDMT pillars & improve outcomes in HFrEF.

🔗 bit.ly/4iZB48Q
January 14, 2026 at 7:15 PM
Tricuspid regurgitation in ❤️‍🩹 HFpEF isn’t benign💡

In 206 pts undergoing invasive exercise testing 🚴‍♀️, moderate–severe TR (vs absent-mild) was linked to ...

⬇️ cardiac reserve — lower peak CO, higher mPAP–CO slope

3.3× higher 5-yr composite HFH or death.

🔗 https://bit.ly/4hZ3YWl
December 18, 2025 at 4:17 PM
🚨 High-output heart failure (HOHF): when more isn’t better!

🤔 Which hemodynamic parameter best predicts outcomes in HOHF?
📉 PCWP, PAPi & PAP → not independently linked to mortality
💡 Elevated cardiac index (CI) = strongest predictor of all-cause mortality.

🔗 bit.ly/47EZC3b
December 17, 2025 at 8:07 PM
🔎 Can provocative testing during RHC unmask HFpEF?

PAWP with🦵passive leg raise & 🚴‍♀️low-workload exercise help narrow the diagnostic gray zone.

🧠 Great for ruling in HFpEF — less reliable for ruling it out!

#Hemodynamics #HFpEF

🔗 https://bit.ly/4oxDZro
December 16, 2025 at 3:23 PM
💭 Should invasive pressure-volume loops be incorporated into diagnostic testing for HFpEF?

‼️Half of pts w/HFpEF can be missed w/RHC even w/exercise! And diagnostic scores for HFpEF have limited sensitivity.

But invasive LV pressure-volume loops can help!

🔗 https://bit.ly/47BRuAu
December 11, 2025 at 3:32 PM
Your next look at the latest heart failure research is here. 🫀

The latest issue of the Journal of Cardiac Failure is now live and ready to be explored.

View the full issue ➜ https://onlinejcf.com/current

#HeartFailure #JCF #AcademicMedicine
December 10, 2025 at 7:57 PM
🚨Can Assisted Aortic Pulsatility Index (API) help guide weaning from IABP?

📊 Assisted API = (Assisted SBP – Assisted DBP) / PCWP

💡 Original research in JCF's Hemodynamics Focus Issue shows assisted API is a sensitive & specific predictor of successful device weaning.

🔗 https://bit.ly/4oZUa0l
December 10, 2025 at 4:47 PM
Pacemakers in HFpEF = more than a marker⚡

HFpEF+PM pts had ...
Worse biatrial/ventricular function
⬇️exercise reserve
⬆️HFH/death (HR ~ 1.8 vs no PM)

Mechanistic insights demonstrating that pacing may compound mechanical & chronotropic limitations.

🔗 https://bit.ly/4peKkYR
December 9, 2025 at 3:02 PM
Final Call for Submissions! 🚨
Focus Issue: Infiltrative & Inflammatory Cardiomyopathies

Your research belongs here. Submit to #JCF’s upcoming Focus Issue.

Learn More: bit.ly/46gZVRq

📆Deadline: Dec. 8, 2025

#CardioTwitter #CardiologyResearch #CallForPapers #Hemodynamics #AcademicMedicine
December 8, 2025 at 4:42 PM
New science 🚨!

Simple 1-point mPAP/CO ratios during 🚴‍♂️CPET w/echo predict outcomes in unexplained dyspnea—matching complex slope methods but with 🔥 higher reproducibility!

Practical tool for assessing #ExercisePH 🫁🫀

#Hemodynmaics #ExerciseTesting #CPET

🔗 https://bit.ly/4patiuW
December 8, 2025 at 3:47 PM
Submit Now - Deadline is Approaching!
Focus Issue: Infiltrative & Inflammatory Cardiomyopathies

Share your insights. Elevate the field. Publish early 2026 with #JCF.

Topics: bit.ly/46gZVRq
📆Deadline: Dec. 8, 2025

#CardioTwitter #HeartFailure #CardiologyResearch #CallForPapers #AcademicMedicine
December 5, 2025 at 4:46 PM
Benefits of ICDs & CRT-Ds⚡️ in HM3 LVAD pts is uncertain.

This analysis of the MOMENTUM-3 trial showed that the presence of these devices was not associated with ⬆️survival, quality of life, or functional capacity in HM3 LVAD pts.

🔗 bit.ly/43c3HZW
December 4, 2025 at 5:08 PM
Deadline Approaching!
Focus Issue: Infiltrative & Inflammatory Cardiomyopathies

Your work can drive discovery. Submit to #JCF’s 2026 Focus Issue.

Explore Topics: bit.ly/46gZVRq
📆Deadline: Dec. 8, 2025

#CardioTwitter #HeartFailure #CardiologyResearch #CallForPapers #AcademicMedicine
December 3, 2025 at 8:54 PM
Effective communication📢 is key in 🫀 Tx!

This article analyzed outcomes of non-native English-speaking (NNES) recipients vs native English-speaking (NES) recipients, and found that there were no diff in 1y & 5y post-HT outcomes📈 between the 2 groups.

🔗 bit.ly/4qGEzEP
December 3, 2025 at 3:43 PM
🖥️ AI can play a key role in prev, early detection & treatment of HF, driven by advancements like multimodal LLMs. But challenges like data privacy, system integration, clinician trust & fairness/bias need to be addressed.

Learn more in this Review: https://bit.ly/4oQyuUr
December 2, 2025 at 6:47 PM
In this VA study, the rates of early 🫀follow-up after HFH were low overall & were only modestly associated w/mortality risk at discharge.

Increasing the visit rate after HFH should be evaluated as a mechanism to improve outcomes after HFH!

🔗 bit.ly/493maeW

🧵
December 2, 2025 at 2:46 PM
​Don't miss this new study on LVAD-supported patients & caregivers.

It identified ⚡8 facilitators & 🚧 7 barriers to values discussions with clinicians following implant.

🫶 It promotes elicitation & incorporation of patient and caregiver values into care

🖇️ bit.ly/48w3ILI
November 25, 2025 at 8:46 PM
🚨 Check out this update to 2023 Japanese Heart Failure Society Scientific Statement on BNP and NT-proBNP to learn how to maximize the use of natriuretic peptides to guide evidence-based treatment & prevention of HF.

🖇️ http://bit.ly/499v4r8
November 24, 2025 at 4:37 PM
How do well pts w/pre-HF understand HF symptoms & illness trajectory?

🚨This study in pts w/ACS found key gaps in pt understanding of HF trajectory & impact on life expectancy. Effective measures are needed to improve knowledge & enhance prevention!

🖇️ http://bit.ly/42DQCIB
November 21, 2025 at 2:47 PM
💡HFpEF represents a major clinical challenge, with women up to 2x more likely to be affected.

The 🌟 SOTA covers the unique cardiometabolic and hormonal challenges to be considered in the screening, diagnosis, & management of HFpEF in women.

🖇️ http://bit.ly/3IUulzD
November 20, 2025 at 6:22 PM
🚨 New Science alert! In this 🔥 article, the authors used the AHA's GWTG HF registry to show that there is significant undertesting & underdiagnosis of ATTR-CM among pts hospitalized for HF, with substantial hospital-level variation across US hospitals.

🔗 http://bit.ly/4hgFGXC
November 14, 2025 at 3:17 PM
Hemodynamics in focus. 🔍

Join Dr. Anu Lala for the Hemodynamics Focus issue of the Journal of Cardiac Failure, exploring all aspects of hemodynamics in heart failure.

Stay Curious and Connected - watch the full video here
🎥 https://youtu.be/dUBnApXqqr8

#JCF #Hemodynamics
November 13, 2025 at 4:52 PM
Could studies of remote monitoring be showing inconsistent impact on outcomes because of clinical workflows? This study sought to look at this very question!

What did they find? Clinical workflows were reported inconsistently and infrequently.

Read more ⬇️
🔗 bit.ly/48ZDGk7
November 12, 2025 at 4:07 PM