Jakob Berner
@jbderm.bsky.social
Pediatric Dermatologist. Physician Scientist.
Inborn errors of immunity. Genetics. Immunology. Rare Diseases. Skin.
Left twitter for obvious reasons… exited to explore this.
Inborn errors of immunity. Genetics. Immunology. Rare Diseases. Skin.
Left twitter for obvious reasons… exited to explore this.
Highly relevant for people working in #pediatrics or anyone working with kids! #obesity changes epigenetic memory of adipose tissue even after weight loss, #education is key
Adipose tissue retains an epigenetic memory of obesity after weight loss - Nature
Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment and potentially contributes to th...
www.nature.com
November 20, 2024 at 9:19 AM
Highly relevant for people working in #pediatrics or anyone working with kids! #obesity changes epigenetic memory of adipose tissue even after weight loss, #education is key
Great paper unraveling the mystery of Cutaneous T cell lymphoma, highly relevant to anyone working in #dermatology
Hello everyone! I am new here and look forward to engaging with the bsky community. My research spans #genomics #immunology #development #dermatology
Today we published a study on the role of skin B cells in cutaneous T cell lymphoma www.nature.com/articles/s41...
Today we published a study on the role of skin B cells in cutaneous T cell lymphoma www.nature.com/articles/s41...
Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microenvironment - Nature Immunology
Haniffa and colleagues provide diagnostic aids, potential biomarkers for disease staging and therapeutic strategies for cutaneous T cell lymphoma.
www.nature.com
November 20, 2024 at 9:04 AM
Great paper unraveling the mystery of Cutaneous T cell lymphoma, highly relevant to anyone working in #dermatology
Reposted by Jakob Berner
Hello everyone! I am new here and look forward to engaging with the bsky community. My research spans #genomics #immunology #development #dermatology
Today we published a study on the role of skin B cells in cutaneous T cell lymphoma www.nature.com/articles/s41...
Today we published a study on the role of skin B cells in cutaneous T cell lymphoma www.nature.com/articles/s41...
Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microenvironment - Nature Immunology
Haniffa and colleagues provide diagnostic aids, potential biomarkers for disease staging and therapeutic strategies for cutaneous T cell lymphoma.
www.nature.com
November 18, 2024 at 8:49 PM
Hello everyone! I am new here and look forward to engaging with the bsky community. My research spans #genomics #immunology #development #dermatology
Today we published a study on the role of skin B cells in cutaneous T cell lymphoma www.nature.com/articles/s41...
Today we published a study on the role of skin B cells in cutaneous T cell lymphoma www.nature.com/articles/s41...
Trying to find/engage a broader #pediatric #dermatology community here. Posting/ reposting papers I find of interest to different scientific communities #IEI #genetics #rarediseases #immunology #dermatology
November 20, 2024 at 9:02 AM
Trying to find/engage a broader #pediatric #dermatology community here. Posting/ reposting papers I find of interest to different scientific communities #IEI #genetics #rarediseases #immunology #dermatology
Novel #IEI due to biallelic variants in the gene coding for Integrin alpha V #ITGAV, incomplete loss of function variants cause neurodevelopmental defects, colitis, and features of #atopy
#pediatricdermatology #genetics #rare diseases
#pediatricdermatology #genetics #rare diseases
rupress.org
November 20, 2024 at 8:58 AM
Great paper describing a novel #IEI due to variants in #ITPR3 #Immunometabolism #genetics #pediatrics
Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency | Journal of Experimental Medicine | Rockefeller University Press
Dominant negative variants in ITPR3, encoding a subunit of the IP3 receptor, cause Ca2+ channel leakiness resulting in ER store depletion and impaired T ce
rupress.org
November 20, 2024 at 8:47 AM
Great paper describing a novel #IEI due to variants in #ITPR3 #Immunometabolism #genetics #pediatrics