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JAMA Psychiatry
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JAMA Psychiatry is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

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Actigraphy-derived measures of sleep phase variability and activity amplitude identified individuals at higher risk of relapse in #Depression, supporting their potential as scalable biomarkers in ongoing monitoring.

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February 11, 2026 at 4:30 PM
First-trimester Z-drug use was not associated with increased risk of major congenital malformations in more than 4 million US pregnancies, providing reassurance for #Pregnancy sleep management. ja.ma/3NVu69K
February 11, 2026 at 12:00 PM
A 6-month peer-supported, technology-enabled #Obesity intervention for veterans with serious mental illness produced greater weight and BMI reductions than usual care, with 22.6% achieving ≥7% weight loss, while cardiorespiratory fitness did not improve.

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February 10, 2026 at 12:00 PM
Neuronal autophagy may bridge stress and psychiatric pathology; ongoing research explores its role in depression, brain regions, biomarkers, and response to antidepressants. ja.ma/45NCEFB
February 9, 2026 at 12:00 PM
#Semaglutide reduced HbA1c and body weight over 26 weeks in individuals with #schizophrenia spectrum disorders and early glycemic abnormalities taking clozapine or olanzapine. bit.ly/4rHCSqu
February 8, 2026 at 12:00 PM
Among individuals with #Schizophrenia and co-occurring #SubstanceUseDisorders, psychological and psychosocial interventions showed limited benefit for symptom reduction and no effect on substance use, except for nicotine.

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February 7, 2026 at 2:00 PM
Neuropsychiatric disorders impose a substantial burden on individuals and societies worldwide.

📢 This Special Communications reflects the broad consensus of experts to advance the agenda for precision psychiatry.

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February 7, 2026 at 12:00 PM
Diagnoses of noncocaine psychostimulant use disorder (UD) among young adult Medicaid enrollees rose sharply from 2001 to 2020, while cocaine UD rates stayed stable. bit.ly/4afup6t
February 6, 2026 at 12:00 PM
Among individuals with #Schizophrenia and co-occurring #SubstanceUseDisorders, psychological and psychosocial interventions showed limited benefit for symptom reduction and no effect on substance use, except for nicotine.

bit.ly/45PtCYH
February 5, 2026 at 3:00 PM
RCT: Daily oxytocin administration combined with positive physical intimacy was linked to improved wound healing and reduced cortisol; oxytocin alone or positive interactions without physical intimacy did not enhance healing.. bit.ly/46uxE92
February 5, 2026 at 12:00 PM
A 6-week #KetogenicDiet produced modest improvement in depressive symptoms vs control in adults with #TreatmentResistantDepression, with no difference in secondary outcomes and uncertain clinical relevance. ja.ma/4abkIpD
February 4, 2026 at 4:30 PM
Among adults with #Depression, complex antidepressant treatment patterns were associated with higher polygenic risk for psychiatric traits but not with sustained use of a single antidepressant. ja.ma/4a86gyC
February 3, 2026 at 12:00 PM
The 2024 US societal cost of #Schizophrenia was $366.8 billion, with unpaid caregiving, lost wages, and reduced quality of life accounting for over 75% of total costs.

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February 2, 2026 at 3:00 PM
Among adults with #Depression, complex antidepressant treatment patterns were associated with higher polygenic risk for psychiatric traits but not with sustained use of a single antidepressant. ja.ma/46lPgUw
January 31, 2026 at 2:00 PM
The 2024 US societal cost of #Schizophrenia was $366.8 billion, with unpaid caregiving, lost wages, and reduced quality of life accounting for over 75% of total costs.

ja.ma/4t0qoLP
January 29, 2026 at 3:00 PM
Among adults with #Depression, complex antidepressant treatment patterns were associated with higher polygenic risk for psychiatric traits but not with sustained use of a single antidepressant. ja.ma/4k3LpkN
January 28, 2026 at 4:30 PM
Early dose reduction or discontinuation after remission from first-episode psychosis increased short-term relapse and lowered quality of life but yielded better researcher-rated functioning at 3 and 4 years. ja.ma/4rg4gM0
January 25, 2026 at 3:00 PM
Elevated plasma #pTau181 and #NfL levels in #AlzheimerDisease patients largely reflect broad neuropsychiatric impairment rather than psychosis alone. ja.ma/4rvSTQf
January 24, 2026 at 3:00 PM
#GLP1 receptor agonists demonstrate potential for reducing alcohol and nicotine use in patients, but further randomized studies are required before clinical adoption for addiction.

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January 23, 2026 at 2:00 PM
Recent US opioid overdose deaths have declined 41%, mainly due to a shrinking at-risk population and plateauing mortality rates.

Continued surveillance is needed to predict and prevent harm.

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January 23, 2026 at 1:00 PM
Ambient #AI scribes increased documentation of neuropsychiatric symptoms in primary care, but were associated with lower rates of psychiatric intervention compared with unscribed visits. ja.ma/4qwC6vX
January 22, 2026 at 3:00 PM
💬 Viewpoint: Clinical application of psychedelics in psychiatry should advance through empirical evaluation of biological, psychological, and contextual factors, emphasizing scientific rigor over uncritical idealism.

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January 21, 2026 at 1:00 PM
Use of psilocybin mushrooms has sharply increased in the US, with variability in potency and frequent co-use with cannabis.

This Special Communication reviews emerging evidence on the public health implications of unregulated psilocybin mushroom use. ja.ma/3LzicBx
January 20, 2026 at 1:00 PM
Yoga as an adjunct to standard buprenorphine therapy for #OpioidUseDisorder accelerated withdrawal stabilization, improved heart rate variability, and reduced anxiety, sleep latency, and pain compared with standard care alone.

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January 19, 2026 at 3:00 PM
Among individuals with #psychosis, #cannabis use increased by 9.53 percentage points after recreational cannabis legalization, a sharper rise than in the general population.

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January 19, 2026 at 12:00 PM