Arezu Jahani-Asl
jahaniarezu.bsky.social
Arezu Jahani-Asl
@jahaniarezu.bsky.social
Canada Research Chair & Associate Professor, University of Ottawa, Adj. Professor, McGill University, arezujahani.com; x:@JahaniArezu; lab: @arezujahanilab
Reposted by Arezu Jahani-Asl
Delighted to share our latest paper out @NatureComms. REST/NRSF is essential for muscle stem cell identity, blocking alternate cell fates—huge congrats to the first author @KorinSahinyan and the rest of the fantastic coauthors.
www.nature.com/articles/s41...
REST/NRSF Preserves muscle stem cell identity by repressing alternate cell fate - Nature Communications
Here the authors show that REST/NRSF represses non-muscle lineage genes in muscle stem cells and progenitors, preserving their identity and differentiation capacity. Loss of REST disrupts gene silenci...
www.nature.com
August 12, 2025 at 8:44 PM
Pleased to share a preprint of our new study, online now; Check it out to find out how a cytokine receptor cross talks with an ion channel to promote glioblastoma progression.

www.biorxiv.org/content/10.1...
An OSMR-CLIC1 cross talk drives key oncogenic pathways in glioblastoma
The cytokine receptor Oncostatin M receptor (OSMR) plays diverse and important roles in several human malignancies, including brain, breast, and pancreatic cancer. In glioblastoma (GB), OSMR orchestra...
www.biorxiv.org
March 11, 2025 at 1:59 PM