Jack Kucinski
@jackkucinski.bsky.social
Ph.D. Candidate at The Ohio State University and Nationwide Children’s Hospital
Pinned
Jack Kucinski
@jackkucinski.bsky.social
· Jul 23
Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo
Kucinski et al. use embryonic zebrafish modeling to understand initial chromatin regulatory
mechanisms of fusion-driven pediatric rhabdomyosarcoma. They found that the PAX3::FOXO1
oncoprotein function...
www.cell.com
I’m happy to share our published work in @cp-cellreports.bsky.social! With zebrafish modeling of rhabdomyosarcoma, we showed that PAX3::FOXO1 utilizes homeobox motif recognition to initially bind closed DNA and activate neural programs present in the human disease. www.cell.com/cell-reports...
I’m happy to share our published work in @cp-cellreports.bsky.social! With zebrafish modeling of rhabdomyosarcoma, we showed that PAX3::FOXO1 utilizes homeobox motif recognition to initially bind closed DNA and activate neural programs present in the human disease. www.cell.com/cell-reports...
Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo
Kucinski et al. use embryonic zebrafish modeling to understand initial chromatin regulatory
mechanisms of fusion-driven pediatric rhabdomyosarcoma. They found that the PAX3::FOXO1
oncoprotein function...
www.cell.com
July 23, 2025 at 3:14 PM
I’m happy to share our published work in @cp-cellreports.bsky.social! With zebrafish modeling of rhabdomyosarcoma, we showed that PAX3::FOXO1 utilizes homeobox motif recognition to initially bind closed DNA and activate neural programs present in the human disease. www.cell.com/cell-reports...