Iván Darío Bravo Tobar. M.D. | M.Sc. | Ph.D.
@idbravotobar.bsky.social
"Science isn't just a job, it's the passion for transforming knowledge into impact."
Physician 🏷️ Academic 🏷️ Clinical Biomedical & Translational Research 🏷️Medical & Scientific Writing 🏷️ Consultant 🏷️ Amateur astronomer.
#MedSky #SciSky #BioChemSky
Physician 🏷️ Academic 🏷️ Clinical Biomedical & Translational Research 🏷️Medical & Scientific Writing 🏷️ Consultant 🏷️ Amateur astronomer.
#MedSky #SciSky #BioChemSky
Dual inhibition of ACLY and ACSS2 by EVT0185 reduces steatosis, hepatic stellate cell activation, and fibrosis in mouse models of MASH: Cell Metabolism www.cell.com/cell-metabol...
Dual inhibition of ACLY and ACSS2 by EVT0185 reduces steatosis, hepatic stellate cell activation, and fibrosis in mouse models of MASH
Di Pastena et al. report that EVT0185, a dual ACLY/ACSS2 inhibitor, improves insulin
sensitivity and steatosis while reducing fibrosis in MASH. By inhibiting acetate-driven
cholesterol biosynthesis, w...
www.cell.com
January 13, 2026 at 9:15 PM
Dual inhibition of ACLY and ACSS2 by EVT0185 reduces steatosis, hepatic stellate cell activation, and fibrosis in mouse models of MASH: Cell Metabolism www.cell.com/cell-metabol...
Risk of Type 2 Diabetes, MASLD and Cardiovascular Disease in People Living With Polycystic Ovary Syndrome url: academic.oup.com/jcem/article...
Risk of Type 2 Diabetes, MASLD and Cardiovascular Disease in People Living With Polycystic Ovary Syndrome
AbstractBackground. Polycystic ovary syndrome (PCOS) is associated with adverse clinical outcomes that may differ according to PCOS phenotype.Methods. Usin
academic.oup.com
January 11, 2026 at 11:05 AM
Risk of Type 2 Diabetes, MASLD and Cardiovascular Disease in People Living With Polycystic Ovary Syndrome url: academic.oup.com/jcem/article...
Dopamine and Mood in Psychotic Disorders url: jamanetwork.com/journals/jam...
Dopamine and Mood in Psychotic Disorders
This cross-sectional study uses fluorine F 18–labeled fluorodopa (18F-DOPA) positron emission tomography (PET) to test for differences in dopamine synthesis capacity between affective syndromes across...
jamanetwork.com
January 6, 2026 at 8:51 PM
Dopamine and Mood in Psychotic Disorders url: jamanetwork.com/journals/jam...
Monogenic cerebral small‐vessel diseases: diagnosis and therapy. Consensus recommendations of the European Academy of Neurology - Mancuso - 2020 - European Journal of Neurology - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
Monogenic cerebral small‐vessel diseases: diagnosis and therapy. Consensus recommendations of the European Academy of Neurology
Background and purpose Guidelines on monogenic cerebral small-vessel disease (cSVD) diagnosis and management are lacking. Endorsed by the Stroke and Neurogenetics Panels of the European Academy of N...
onlinelibrary.wiley.com
January 4, 2026 at 8:37 PM
Monogenic cerebral small‐vessel diseases: diagnosis and therapy. Consensus recommendations of the European Academy of Neurology - Mancuso - 2020 - European Journal of Neurology - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
Peripheral Neuropathy: A Review url: jamanetwork.com/journals/jam...
Peripheral Neuropathy: A Review
This review discusses the pathophysiology, clinical presentation, diagnosis, and treatment of length-dependent peripheral neuropathy.
jamanetwork.com
January 4, 2026 at 3:13 PM
Peripheral Neuropathy: A Review url: jamanetwork.com/journals/jam...
Predatory journals: what can we do to protect their prey? - The Lancet www.thelancet.com/journals/lan...
Predatory journals: what can we do to protect their prey?
A growing number of entities misrepresent themselves as scholarly journals for financial
gain despite not meeting scholarly publishing standards.1,2 As editors and members
of the International Committ...
www.thelancet.com
January 2, 2026 at 11:12 PM
Predatory journals: what can we do to protect their prey? - The Lancet www.thelancet.com/journals/lan...
Definition and diagnostic criteria of clinical obesity - The Lancet Diabetes & Endocrinology www.thelancet.com/journals/lan...
Definition and diagnostic criteria of clinical obesity
Current BMI-based measures of obesity can both underestimate and overestimate adiposity
and provide inadequate information about health at the individual level, which undermines
medically-sound approa...
www.thelancet.com
January 1, 2026 at 3:23 PM
Definition and diagnostic criteria of clinical obesity - The Lancet Diabetes & Endocrinology www.thelancet.com/journals/lan...
Glymphatic dysfunction in Alzheimer’s disease: A critical appraisal | Science www.science.org/doi/10.1126/...
Glymphatic dysfunction in Alzheimer’s disease: A critical appraisal
Thirteen years after the initial publication defining the glymphatic system, we critically reappraise the role of its dysfunction in Alzheimer’s disease (AD). Our understanding of glymphatic function ...
www.science.org
December 28, 2025 at 5:16 PM
Glymphatic dysfunction in Alzheimer’s disease: A critical appraisal | Science www.science.org/doi/10.1126/...
Natural daylight during office hours improves glucose control and whole-body substrate metabolism: Cell Metabolism www.cell.com/cell-metabol...
Natural daylight during office hours improves glucose control and whole-body substrate metabolism
Harmsen et al. compared the metabolic impact of natural daylight vs. artificial office
lighting in individuals with type 2 diabetes over 5 days. Daylight improved glucose
homeostasis, whole-body fat u...
www.cell.com
December 27, 2025 at 11:50 AM
Natural daylight during office hours improves glucose control and whole-body substrate metabolism: Cell Metabolism www.cell.com/cell-metabol...
Targeting γδ T cells for immunotherapies against colorectal cancer: Trends in Immunology www.cell.com/trends/immun...
Targeting γδ T cells for immunotherapies against colorectal cancer
The advancement of immunotherapy faces significant challenges, including extending
its benefits to a growing number of patients and enhancing its efficacy across different
tumor types. In this context...
www.cell.com
December 22, 2025 at 12:33 AM
Targeting γδ T cells for immunotherapies against colorectal cancer: Trends in Immunology www.cell.com/trends/immun...
Polarized Signatures of the Earth Through Time: An Outlook for the Habitable Worlds Observatory
doi.org/10.3847/1538...
via @ioppublishing.bsky.social
doi.org/10.3847/1538...
via @ioppublishing.bsky.social
Polarized Signatures of the Earth Through Time: An Outlook for the Habitable Worlds Observatory
Polarized Signatures of the Earth Through Time: An Outlook for the Habitable Worlds Observatory, Goodis Gordon, Kenneth E., Karalidi, Theodora, Bott, Kimberly M., Wogan, Nicholas F., Arney, Giada N., ...
doi.org
December 21, 2025 at 12:18 AM
Polarized Signatures of the Earth Through Time: An Outlook for the Habitable Worlds Observatory
doi.org/10.3847/1538...
via @ioppublishing.bsky.social
doi.org/10.3847/1538...
via @ioppublishing.bsky.social
Targeting H3N2 influenza: advancements in treatment and vaccine strategies: Expert Review of Anti-infective Therapy: Vol 23, No 1 www.tandfonline.com/doi/abs/10.1...
Targeting H3N2 influenza: advancements in treatment and vaccine strategies
The emergence of the H3N2 influenza virus in 1968 marked a significant event as it crossed the species barrier. This shift led to a pandemic, resulting in the deaths of one million people globally ...
www.tandfonline.com
December 18, 2025 at 2:51 PM
Targeting H3N2 influenza: advancements in treatment and vaccine strategies: Expert Review of Anti-infective Therapy: Vol 23, No 1 www.tandfonline.com/doi/abs/10.1...
