Iván Darío Bravo Tobar. M.D. | M.Sc. | Ph.D.
@idbravotobar.bsky.social
"Science isn't just a job, it's the passion for transforming knowledge into impact."
Physician 🏷️ Academic 🏷️ Clinical Biomedical & Translational Research 🏷️Medical & Scientific Writing 🏷️ Consultant 🏷️ Amateur astronomer.
#MedSky #SciSky #BioChemSky
Physician 🏷️ Academic 🏷️ Clinical Biomedical & Translational Research 🏷️Medical & Scientific Writing 🏷️ Consultant 🏷️ Amateur astronomer.
#MedSky #SciSky #BioChemSky
Towards a heuristic view of managerial heuristics: Integrating divergent perspectives - Atanasiu - 2025 - International Journal of Management Reviews - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Towards a heuristic view of managerial heuristics: Integrating divergent perspectives
Managerial heuristics – simple methods for solving problems – are critical for key functions, such as deciding, strategizing, and organizing. Yet, research on managerial heuristics has been siloed in...
onlinelibrary.wiley.com
November 19, 2025 at 1:28 PM
Towards a heuristic view of managerial heuristics: Integrating divergent perspectives - Atanasiu - 2025 - International Journal of Management Reviews - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Haptoglobin Genotypes in Hidradenitis Suppurativa: Haptoglobin 2–2 Genotype Is Associated With Familial Hidradenitis Suppurativa and More Flares - Abu Rached - 2025 - International Journal of Dermatology - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Haptoglobin Genotypes in Hidradenitis Suppurativa: Haptoglobin 2–2 Genotype Is Associated With Familial Hidradenitis Suppurativa and More Flares
Background
Haptoglobin (Hp) is an acute-phase protein and an independent marker for hidradenitis suppurativa (HS) severity. The different Hp genotypes (Hp 1–1, Hp 1–2, and Hp 2–2) differ in their an.....
onlinelibrary.wiley.com
November 18, 2025 at 5:46 PM
Haptoglobin Genotypes in Hidradenitis Suppurativa: Haptoglobin 2–2 Genotype Is Associated With Familial Hidradenitis Suppurativa and More Flares - Abu Rached - 2025 - International Journal of Dermatology - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
An overview of the laboratory diagnosis of Pneumocystis jirovecii pneumonia | Journal of Clinical Microbiology journals.asm.org/doi/full/10....
An overview of the laboratory diagnosis of Pneumocystis jirovecii pneumonia | Journal of Clinical Microbiology
Pneumocystis jirovecii, formerly known as Pneumocystis carinii (1), is an opportunistic fungal pathogen, first identified by Carlos Chagas in Brazil
in 1909. Chagas studied the protozoa Trypanosoma cr...
journals.asm.org
November 18, 2025 at 12:53 AM
An overview of the laboratory diagnosis of Pneumocystis jirovecii pneumonia | Journal of Clinical Microbiology journals.asm.org/doi/full/10....
Full article: Crosstalk Between Keratinocytes and T Cells in Ulcerative Oral Mucosal Diseases: Mechanisms of Epithelial Dysfunction and Therapeutic Perspectives www.tandfonline.com/doi/full/10....
Crosstalk Between Keratinocytes and T Cells in Ulcerative Oral Mucosal Diseases: Mechanisms of Epithelial Dysfunction and Therapeutic Perspectives
Erosive and ulcerative oral mucosal diseases (OMDs) are characterized by persistent inflammation, epithelial barrier disruption, and impaired tissue repair, including oral lichen planus (OLP), disc...
www.tandfonline.com
November 14, 2025 at 4:57 PM
Full article: Crosstalk Between Keratinocytes and T Cells in Ulcerative Oral Mucosal Diseases: Mechanisms of Epithelial Dysfunction and Therapeutic Perspectives www.tandfonline.com/doi/full/10....
Higher vitamin B12 from mid‐ to late life is related to slower rates of cognitive decline - Marino - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/full/10....
Higher vitamin B12 from mid‐ to late life is related to slower rates of cognitive decline
INTRODUCTION Evidence is needed to evaluate whether low vitamin B12 from mid- to late life, either alone or in the presence of elevated folate, is associated with cognitive decline. METHODS Partic...
alz-journals.onlinelibrary.wiley.com
November 13, 2025 at 8:33 PM
Higher vitamin B12 from mid‐ to late life is related to slower rates of cognitive decline - Marino - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/full/10....
Lithium for Bipolar Disorder and Thyroid Dysfunction and Chronic Kidney Disease url: jamanetwork.com/journals/jam...
Lithium for Bipolar Disorder and Thyroid Dysfunction and Chronic Kidney Disease
This cohort study analyzes associations of lithium treatment with hyperthyroidism, hypothyroidism, and chronic kidney disease among individuals with bipolar disorder in Hong Kong.
jamanetwork.com
November 11, 2025 at 3:49 PM
Lithium for Bipolar Disorder and Thyroid Dysfunction and Chronic Kidney Disease url: jamanetwork.com/journals/jam...
Does photobiomodulation alter mitochondrial dynamics? - Trajano - 2025 - Photochemistry and Photobiology - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Does photobiomodulation alter mitochondrial dynamics?
Photobiomodulation regulates the expression levels of mitochondrial fusion and fission proteins. Studies has demonstrated that photobiomodulation increases the levels of mitochondrial fusion proteins...
onlinelibrary.wiley.com
November 11, 2025 at 12:38 AM
Does photobiomodulation alter mitochondrial dynamics? - Trajano - 2025 - Photochemistry and Photobiology - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
New landscape of the diagnosis of Alzheimer's disease - The Lancet www.thelancet.com/journals/lan...
New landscape of the diagnosis of Alzheimer's disease
Alzheimer's disease involves a drastic departure from the cognitive, functional, and
behavioural trajectory of normal ageing, and is both a dreaded and highly prevalent
cause of disability to individu...
www.thelancet.com
November 11, 2025 at 12:36 AM
New landscape of the diagnosis of Alzheimer's disease - The Lancet www.thelancet.com/journals/lan...
B cells targeting parasites capture spatially linked antigens to secure T cell help | Science Immunology www.science.org/doi/10.1126/...
B cells targeting parasites capture spatially linked antigens to secure T cell help
Antigen location orchestrates T cell–B cell collaboration in response to large pathogens.
www.science.org
November 9, 2025 at 6:21 PM
B cells targeting parasites capture spatially linked antigens to secure T cell help | Science Immunology www.science.org/doi/10.1126/...
Polysomnographic features of hypoglossal nerve stimulation efficacy: Looking deeper than the apnea‐hypopnea index - So - 2025 - Laryngoscope Investigative Otolaryngology - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Polysomnographic features of hypoglossal nerve stimulation efficacy: Looking deeper than the apnea‐hypopnea index
Efficacy of hypoglossal nerve stimulation (HGNS) for obstructive sleep apnea may be characterized by strategic on–off protocols during postoperative polysomnographic fine-tune studies. Respiratory de...
onlinelibrary.wiley.com
November 9, 2025 at 4:55 PM
Polysomnographic features of hypoglossal nerve stimulation efficacy: Looking deeper than the apnea‐hypopnea index - So - 2025 - Laryngoscope Investigative Otolaryngology - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Telomere Shortening in Interstitial Lung Disease: Challenges and Promises - Jin - 2025 - The Clinical Respiratory Journal - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Telomere Shortening in Interstitial Lung Disease: Challenges and Promises
Telomerase abnormalities such as related gene mutations lead to decrease in telomerase activity and telomere shortening. Individual cells undergoing continuous division exhibit telomere shortening. A....
onlinelibrary.wiley.com
November 9, 2025 at 4:52 PM
Telomere Shortening in Interstitial Lung Disease: Challenges and Promises - Jin - 2025 - The Clinical Respiratory Journal - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Orexin Deficiency in Narcolepsy: Molecular Mechanisms, Clinical Phenotypes, and Emerging Therapeutic Frontiers - Rauf - 2025 - Brain and Behavior - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Orexin Deficiency in Narcolepsy: Molecular Mechanisms, Clinical Phenotypes, and Emerging Therapeutic Frontiers
Orexin deficiency drives narcolepsy Type 1, leading to excessive daytime sleepiness, cataplexy, and REM intrusions. This review highlights recent advances (2023–2025) in molecular mechanisms, diagnos...
onlinelibrary.wiley.com
November 9, 2025 at 4:47 PM
Orexin Deficiency in Narcolepsy: Molecular Mechanisms, Clinical Phenotypes, and Emerging Therapeutic Frontiers - Rauf - 2025 - Brain and Behavior - Wiley Online Library onlinelibrary.wiley.com/doi/full/10....
Remodeling of T and endothelial cells during total neoadjuvant therapy in rectal cancer: Cancer Cell www.cell.com/cancer-cell/...
Remodeling of T and endothelial cells during total neoadjuvant therapy in rectal cancer
Gao et al. characterize the tumor microenvironment dynamics following total neoadjuvant
therapy (TNT) in locally advanced rectal cancer using a multi-omics approach. They
uncover a unique interaction ...
www.cell.com
November 8, 2025 at 11:00 PM
Remodeling of T and endothelial cells during total neoadjuvant therapy in rectal cancer: Cancer Cell www.cell.com/cancer-cell/...
European Study of Prostate Cancer Screening — 23-Year Follow-up | New England Journal of Medicine www.nejm.org/doi/full/10....
European Study of Prostate Cancer Screening — 23-Year Follow-up | NEJM
The European Randomized Study of Screening for Prostate Cancer (ERSPC) was initiated
in 1993 to assess the effect of prostate-specific antigen (PSA) testing on prostate
cancer mortality. Because de...
www.nejm.org
November 1, 2025 at 3:34 AM
European Study of Prostate Cancer Screening — 23-Year Follow-up | New England Journal of Medicine www.nejm.org/doi/full/10....
Psychological Balances in the Digital World: Dynamic Relationships Among Social Media Addiction, Depression, Anxiety, Academic Self-Efficacy, General Belongingness, and Life Satisfaction: The Journal of Genetic Psychology: Vol 186, No 2 www.tandfonline.com/doi/abs/10.1...
Psychological Balances in the Digital World: Dynamic Relationships Among Social Media Addiction, Depression, Anxiety, Academic Self-Efficacy, General Belongingness, and Life Satisfaction
In the present era, the rapidly growing social media trends of the digital age have the potential to affect the psychological well-being of individuals. In this context, understanding how Social Me...
www.tandfonline.com
October 25, 2025 at 11:56 PM
Psychological Balances in the Digital World: Dynamic Relationships Among Social Media Addiction, Depression, Anxiety, Academic Self-Efficacy, General Belongingness, and Life Satisfaction: The Journal of Genetic Psychology: Vol 186, No 2 www.tandfonline.com/doi/abs/10.1...
