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i2sysbio.es
I2SysBio
@i2sysbio.es
950 followers 120 following 180 posts
Institute for Integrative Systems Biology, a joint research centre of @uv.es and @csic.es 🌐 https://i2sysbio.es/ 🇪🇸
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i2sysbio.es
I2SysBio @i2sysbio.es · Nov 20
Our research institute I2SysBio🇪🇸 has created a starter pack for researchers in systems biology, everybody is welcome, write us if you want to be added 🔬🧫🧬🖥🦑🦠🌱🦟🪳🪸🌾
i2sysbio.es
‼️New PhD position at the I2SYSBIO within the MSCA-COFUND SYNBIO-CSIC doctoral network for advanced training in Synthetic and Engineering Biology.

🗓️Apply by February 26, 2026.

www.i2sysbio.es/position/15/

@pablocarb.bsky.social @dicv.csic.es @uv.es @csic.es
i2sysbio - Position
www.i2sysbio.es
December 26, 2025 at 9:45 AM
i2sysbio.es
‼️👏@jtmatus.bsky.social has been officially appointed to serve within the #PIFI group at Chinese Academy of Sciences (CAS)

PIFI serves as a bridge linking global talent with leading scientific institutions in China, supporting high level research and fostering intercultural scientific collaboration.
December 23, 2025 at 12:32 PM
Reposted by I2SysBio
sfelenalab.bsky.social
Izan Melero defends his thesis on how host developmental stage shapes viral evolution www.i2sysbio.es/communicatio...
Izan Melero defends his thesis on how host developmental stage shapes viral evolution
<p><strong>This thesis, supervised by Santiago F. Elena and Rub&eacute;n Gonz&aacute;lez, explores the relationships between host developmental stages and virus infection and evolution on different ho...
www.i2sysbio.es
December 19, 2025 at 1:12 PM
i2sysbio.es
🎥El investigador @fgonzalef.bsky.social lidera el grupo de Epidemiología Molecular en el #I2SysBio (@csic.es- @uv.es)

➡️Mira esta breve presentación si quieres saber más sobre su trayectoria y sus principales líneas de investigación.

@dicv.csic.es

www.youtube.com/watch?v=W4Ja...
Interview of Fernando González, Principal Investigator of the Molecular Epidemiology group
YouTube video by Institute for Integrative Systems Biology I2SysBio
www.youtube.com
December 19, 2025 at 9:05 AM
Reposted by I2SysBio
dicv.csic.es
Conoce la actualidad y agenda de los centros @csic.es en la Comunitat Valenciana en nuestro boletín #SemanaCSIC:

delegacion.comunitatvalenciana.csic.es/boletin-sema...

@comunicacion.iats.csic.es @i2sysbio.es @itq-upvcsic.bsky.social @ibmcp.bsky.social @neuroalc.bsky.social
@iatacsic.bsky.social
December 12, 2025 at 12:54 PM
Reposted by I2SysBio
dzunkovam.bsky.social
My colleagues from @i2sysbio.es led by Santiago Elena @sfelena.bsky.social published a paper in iScience on how Orsay #virus infection influences C. elegans development
#microsky
December 15, 2025 at 9:23 PM
i2sysbio.es
🎥🌊@guillemsalazar.bsky.social lidera el grupo de Ecología de Microbiomas en el #I2SysBio (@csic.es-@uv.es).

Su laboratorio investiga las estrategias microbianas para hacer frente a los cambios ambientales, con un enfoque especial en los microbios marinos.

www.youtube.com/watch?v=_5Td...
Interview of Guillem Salazar, Principal Investigator of the Microbiome Ecology group
YouTube video by Institute for Integrative Systems Biology I2SysBio
www.youtube.com
December 12, 2025 at 9:57 AM
Reposted by I2SysBio
dzunkovam.bsky.social
VEGA arrived to our institute @i2sysbio.es . Thank you, Ana Conesa @anaconesa.bsky.social !!!
anaconesa.bsky.social Ana Conesa @anaconesa.bsky.social · 17d
I am SOOO excited to welcome our brand-new VEGA instrument, made possible through a collaboration among @uv.es @i2sysbio.es and @pacbio.bsky.social . Months ago, we fantasized about having one, and now this is a reality. I can´t wait to run the many projects we have in the pipeline!
December 10, 2025 at 8:02 AM
Reposted by I2SysBio
anaconesa.bsky.social
I am SOOO excited to welcome our brand-new VEGA instrument, made possible through a collaboration among @uv.es @i2sysbio.es and @pacbio.bsky.social . Months ago, we fantasized about having one, and now this is a reality. I can´t wait to run the many projects we have in the pipeline!
December 10, 2025 at 7:37 AM
i2sysbio.es
Personal investigador del #I2SysBio (@csic.es-@uv.es) y del Laboratorio de Proteínas de Membrana de la @ccbiologiquesuv.bsky.social han identificado una región clave de la proteína Spike del SARS-CoV-2, esencial para que el virus pueda entrar en las células humanas.

www.i2sysbio.es/communicatio...
The role of the coronavirus ‘anchor’ revealed: the least-known part of the spike protein is key to infection
<p>Research conducted by the University of Valencia and the Spanish National Research Council (CSIC) has revealed that a previously little-studied region of the SARS-CoV-2 spike protein is crucial for...
www.i2sysbio.es
December 9, 2025 at 11:18 AM
Reposted by I2SysBio
csic.es
🦠Nuevas claves sobre cómo el coronavirus lleva a cabo la infección 

🔬Una región de la proteína Spike actúa como una llave que permite la entrada del virus SARS-CoV-2 a las células

👉 http://tiny.cc/rj6w001
December 9, 2025 at 9:04 AM
Reposted by I2SysBio
julipereto.bsky.social
@i2sysbio.es
csic-vaact.bsky.social Áreas Científico-Técnicas VAACT-CSIC @csic-vaact.bsky.social · 23d
🚀 OPEN PhD POSITIONS in #SyntheticBiology!
Join #SYNBIO-CSIC, an EU-funded doctoral programme by CSIC:
✔ 20 positions
✔ Cutting-edge research in #EngineeringBiology
✔ Interdisciplinary training for future leaders
➡️https://lifehub.csic.es/synbio-cofund/
#MSCACOFUND #SYNBIO
December 4, 2025 at 5:34 PM
Reposted by I2SysBio
dzunkovam.bsky.social
My @i2sysbio.es colleagues Lucas Mora, Rafael Sanjuan @rafa-sanjuan.bsky.social and Pilar Domingo Calap @pilardomingoc.bsky.social published a paper about reversible phenotypic resistance to phages in Klebsiella. 👏👏 Congratulations! 🧬🖥🧪🦠🧫 #microsky #viruses #phages
www.cell.com/iscience/ful...
Reversible phenotypic resistance to phage infection via capsule downregulation in Klebsiella pneumoniae
Molecular biology; Microbiology; Cell biology
www.cell.com
December 6, 2025 at 7:27 AM
i2sysbio.es
📹💊@arnaumontagud.bsky.social lidera el grupo de Modelización en Biología de Sistemas en el #I2SysBio ( @csic.es - @uv.es), en el que trabajan por el desarrollo de gemelos digitales.

➡️Puedes conocer más detalles a través de este vídeo de presentación.

@dicv.csic.es
www.youtube.com/watch?v=rQQo...
Interview of Arnau Montagud, Principal Investigator of the Systems Biology Modelling group
YouTube video by Institute for Integrative Systems Biology I2SysBio
www.youtube.com
December 5, 2025 at 12:37 PM
Reposted by I2SysBio
uv.es
#UV | 🔬 Un estudi revela el mecanisme evolutiu que duen a terme els fags –virus amb interés terapèutic– per a infectar bacteris multiresistents. Els resultats obrin noves vies per a desenvolupar teràpies més eficaces enfront d’aquests bacteris. @i2sysbio.es 

Un estudi revela com certs virus evolucionen i s’adapten per a infectar nous bacteris
Un estudi liderat per Celia Ferriol-González i Pilar Domingo-Calap, investigadores de l’Institut de Biologia Integrativa de Sistemes (centre mixt de la Universitat de València, UV, i del Consell Superior d’Investigacions Científiques, CSIC), revela...
ir.uv.es
December 2, 2025 at 12:30 PM
Reposted by I2SysBio
csic.es
🦠 Un estudio revela cómo ciertos virus evolucionan para infectar bacterias de relevancia clínica

🔬Este hallazgo del @i2sysbio.es #CSIC puede ayudar a luchar contra las infecciones por bacterias resistentes a los antibióticos, un fenómeno en aumento

👉 https://f.mtr.cool/byivpwyazp
December 2, 2025 at 9:10 AM
Reposted by I2SysBio
dicv.csic.es
🔬🦠 Un estudio del @i2sysbio.es revela cómo cierto tipo de fagos evoluciona y se adapta para atacar a diferentes bacterias.

💉💊 Un paso más hacia terapias personalizadas frente a bacterias resistentes a antibióticos.

@csic.es @uv.es

delegacion.comunitatvalenciana.csic.es/un-estudio-r...
Recreación de un fago, un virus que podría ser una solución contra las bacterias resistentes a antibióticos. / Vicente Cases Arrué.
December 2, 2025 at 9:12 AM
i2sysbio.es
📹El investigador Manel Porcar lidera el grupo de Biotecnología y Biología Sintética en el #I2SysBio (@csic.es-@uv.es)

Puedes conocer más sobre su trayectoria y sobre el proyecto
@micro4biogas.eu a través de esta entrevista.

@dicv.csic.es

www.youtube.com/watch?v=W2kd...
Interview of Manel Porcar, Principal Investigator of the Biotechnology and Synthetic Biology group
YouTube video by Institute for Integrative Systems Biology I2SysBio
www.youtube.com
November 28, 2025 at 12:23 PM
Reposted by I2SysBio
dzunkovam.bsky.social
Our institute @i2sysbio.es published news on our article published in #ISME Communications. We developed a #bioinformatics tool to demultiplex reads from #Atrandi microfluids platform @atrandi.bsky.social for microbial #single-cell genomics, great for detection of #phages & #viruses
👩‍🔬🧬🧪🦠🧫🖥 #microsky
November 28, 2025 at 10:34 AM
Reposted by I2SysBio
vicentarnau.bsky.social
El @i2sysbio.es desarrolla una herramienta bioinformática que consigue estudiar el genoma de bacterias individuales con sus virus infecciosos asociados www.i2sysbio.es/communicatio...
Programado por @vicentarnau.bsky.social y dirigido por @dzunkovam.bsky.social
November 28, 2025 at 11:21 AM
i2sysbio.es
L'investigador de l'I2SysBio @julipereto.bsky.social analitza el cas del bacteri que utilitzava arsènic per a créixer, anunciat per la NASA el 2010 i desmentit després.

🎙️Un episodi de Mètode molt interessant sobre comunicació científica i sensacionalisme!
November 28, 2025 at 9:50 AM
Reposted by I2SysBio
pilardomingoc.bsky.social
Very proud of @celiaferriolg.bsky.social! Amazing experimental evolution for phage optimization and for host range expansion, allowing us to understand the evolvability of phage RBPs. This work is part of her PhD project at the #EnBivirLab @i2sysbio.es @uv.es @ccbiologiquesuv.bsky.social
plosbiology.org PLOS Biology @plosbiology.org · 29d
Capsule diversity limits #phage host range by affecting receptor-binding protein (RBP) interactions in capsulated #bacteria. @pilardomingoc.bsky.social &co show that generalist phages evolve host range via RBP mutation & recombination, but specialists remain stable @plosbiology.org 🧪 plos.io/48nvOqY
Graphic representation of the recombination events in the Sugarlandvirus I and J variants. Top left: Representation of the variants isolates in the different strains in the three lines. Genome fragments of each parent are represented in a different color. Regions with the most abundant recombination events are marked and associated with a schematic representation of the functional annotation and intergenomic similarity between the two parental phages. Bottom left: 3D folding of the RBPγ. The consensus recombinant region, which is associated with the infection of the K-type 47, is represented in light orange. Variable positions detected in the protein sequence alignment of the variants are represented as hot pink spheres. The table indicates the percentage of identity of the parental protein sequences in three protein regions limited by the amino acids indicated. Right: Transmission electron microscopy (TEM) image of Klebsiella myoviruses artificially coloured, showing their characteristic contractile tails and icosahedral capsids. Image acquired by the Environmental and Biomedical Virology group (Institute for Integrative Systems Biology, Universitat de València-CSIC).
November 28, 2025 at 9:36 AM
i2sysbio.es
🦠 Researchers at #I2SysBio (@csic.es - @uv.es) develop a bioinformatics tool to study the genome of individual bacteria and their associated infectious viruses.

➡️A study led by @dzunkovam.bsky.social and published in ISME Communications.

@dicv.csic.es

www.i2sysbio.es/communicatio...
I2SysBio develops a bioinformatics tool to study the genome of individual bacteria and their associated infectious viruses
<p>Researchers at the Institute of Integrative Systems Biology (I2SysBio), a joint centre of the University of Valencia and the Spanish National Research Council (CSIC), have developed <strong>CleanBa...
www.i2sysbio.es
November 28, 2025 at 9:41 AM