Heinz Freisling
@hfreisling.bsky.social
Hi, I am epidemiologist at the International Agency for Research on Cancer. Posts reflect my own opinions and views.
This 👉
I’m going to halve my publication output. You should consider slow science, too www.nature.com/articles/d41...
I’m going to halve my publication output. You should consider slow science, too www.nature.com/articles/d41...
I’m going to halve my publication output. You should consider slow science, too
If we don’t slow down, the research enterprise is going to crash, argues Adrian Barnett.
www.nature.com
January 23, 2026 at 9:12 AM
This 👉
I’m going to halve my publication output. You should consider slow science, too www.nature.com/articles/d41...
I’m going to halve my publication output. You should consider slow science, too www.nature.com/articles/d41...
The rich stopped buying yachts the year time went on sale www.nature.com/articles/d41...
The rich stopped buying yachts the year time went on sale
Second thoughts.
www.nature.com
January 23, 2026 at 9:07 AM
The rich stopped buying yachts the year time went on sale www.nature.com/articles/d41...
The academic community failed Wikipedia for 25 years — now it might fail us www.nature.com/articles/d41...
The academic community failed Wikipedia for 25 years — now it might fail us
Artificial-intelligence systems are feeding on Wikipedia without giving back, and academic indifference is threatening the survival of what is arguably the most widely used reference work on the plane...
www.nature.com
January 17, 2026 at 10:55 AM
The academic community failed Wikipedia for 25 years — now it might fail us www.nature.com/articles/d41...
👋Lower socioeconomic position = higher #multimorbidity of #cancer #diabetes & #CVDs.
👉Healthy lifestyle partly mediates this link, more so in men (29%) than women (11%).
jech.bmj.com/content/80/1/3
👉Healthy lifestyle partly mediates this link, more so in men (29%) than women (11%).
jech.bmj.com/content/80/1/3
Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation...
Background Multimorbidity is socially patterned, with lower socioeconomic position (SEP) linked to higher risk. We examined whether a Healthy Lifestyle Index (HLI) mediates the SEP–multimorbidity asso...
jech.bmj.com
December 14, 2025 at 11:45 AM
👋Lower socioeconomic position = higher #multimorbidity of #cancer #diabetes & #CVDs.
👉Healthy lifestyle partly mediates this link, more so in men (29%) than women (11%).
jech.bmj.com/content/80/1/3
👉Healthy lifestyle partly mediates this link, more so in men (29%) than women (11%).
jech.bmj.com/content/80/1/3
A ten-year drive to credit authors for their work — and why there’s still more to do www.nature.com/articles/d41...
A ten-year drive to credit authors for their work — and why there’s still more to do
Information about the roles of each author of a paper can help to build trust, integrity and responsible research assessment. Coordinated efforts are needed to consolidate progress.
www.nature.com
November 27, 2025 at 1:09 PM
A ten-year drive to credit authors for their work — and why there’s still more to do www.nature.com/articles/d41...
👉 With Lancet's refined definition of #obesity, we found clinical obesity (excess fat + organ dysfunction) linked to a 56% higher #mortality vs. no obesity.
👉 #BMI alone misses key risks.
@michaeljstein.bsky.social
@uniregensburg.bsky.social
🙏 @wcrf.org
👉 10.1001/jamainternmed.2025.4978
👉 #BMI alone misses key risks.
@michaeljstein.bsky.social
@uniregensburg.bsky.social
🙏 @wcrf.org
👉 10.1001/jamainternmed.2025.4978
October 28, 2025 at 12:27 PM
👉 With Lancet's refined definition of #obesity, we found clinical obesity (excess fat + organ dysfunction) linked to a 56% higher #mortality vs. no obesity.
👉 #BMI alone misses key risks.
@michaeljstein.bsky.social
@uniregensburg.bsky.social
🙏 @wcrf.org
👉 10.1001/jamainternmed.2025.4978
👉 #BMI alone misses key risks.
@michaeljstein.bsky.social
@uniregensburg.bsky.social
🙏 @wcrf.org
👉 10.1001/jamainternmed.2025.4978
Regression adjustment for causal inference bmjmedicine.bmj.com/content/4/1/...
Regression adjustment for causal inference
Causal inference identifies and quantifies the effect of an exposure (the hypothetical cause) to an outcome. While randomised controlled trial design is the preferred method for establishing and measu...
bmjmedicine.bmj.com
October 28, 2025 at 7:48 AM
Regression adjustment for causal inference bmjmedicine.bmj.com/content/4/1/...
👋Imaging-derived organ measurements outperform #BMI in predicting risks for #diabetes, #cancer & #mortality.
👉Advanced imaging may redefine how we assess obesity-related health risks. #ObesityResearch
doi.org/10.1186/s129...
👉Advanced imaging may redefine how we assess obesity-related health risks. #ObesityResearch
doi.org/10.1186/s129...
Client Challenge
doi.org
October 13, 2025 at 4:53 PM
👋Imaging-derived organ measurements outperform #BMI in predicting risks for #diabetes, #cancer & #mortality.
👉Advanced imaging may redefine how we assess obesity-related health risks. #ObesityResearch
doi.org/10.1186/s129...
👉Advanced imaging may redefine how we assess obesity-related health risks. #ObesityResearch
doi.org/10.1186/s129...
👋MR analyses (~40K Europeans) showed causal links between specific fat depots and #cancer
👉Liver fat ↑ liver cancer risk
👉Pancreas fat ↑ ovarian cancer risk
👉Abdominal subcutaneous adipose tissue ↑ endometrial ↑ liver, ↑ esophageal, ↑ovarian cancer
@wcrf.org
👉 doi.org/10.1093/jnci...
👉Liver fat ↑ liver cancer risk
👉Pancreas fat ↑ ovarian cancer risk
👉Abdominal subcutaneous adipose tissue ↑ endometrial ↑ liver, ↑ esophageal, ↑ovarian cancer
@wcrf.org
👉 doi.org/10.1093/jnci...
Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis
AbstractIntroduction. There is convincing evidence that overall adiposity increases the risks of several cancers. Whether the distribution of adiposity pla
doi.org
September 28, 2025 at 12:36 PM
👋MR analyses (~40K Europeans) showed causal links between specific fat depots and #cancer
👉Liver fat ↑ liver cancer risk
👉Pancreas fat ↑ ovarian cancer risk
👉Abdominal subcutaneous adipose tissue ↑ endometrial ↑ liver, ↑ esophageal, ↑ovarian cancer
@wcrf.org
👉 doi.org/10.1093/jnci...
👉Liver fat ↑ liver cancer risk
👉Pancreas fat ↑ ovarian cancer risk
👉Abdominal subcutaneous adipose tissue ↑ endometrial ↑ liver, ↑ esophageal, ↑ovarian cancer
@wcrf.org
👉 doi.org/10.1093/jnci...
👋Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis - The Lancet Healthy Longevity
#cancer #cvd #diabetes
www.thelancet.com/journals/lan...
#cancer #cvd #diabetes
www.thelancet.com/journals/lan...
Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis
A healthy plant-based diet might reduce the burden of multimorbidity of cancer and
cardiometabolic diseases among middle-aged and older adults.
www.thelancet.com
August 21, 2025 at 9:01 AM
👋Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis - The Lancet Healthy Longevity
#cancer #cvd #diabetes
www.thelancet.com/journals/lan...
#cancer #cvd #diabetes
www.thelancet.com/journals/lan...
Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis - The Lancet Public Health www.thelancet.com/journals/lan...
Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis
Although 10 000 steps per day can still be a viable target for those who are more
active, 7000 steps per day is associated with clinically meaningful improvements in
health outcomes and might be a mor...
www.thelancet.com
August 19, 2025 at 6:28 AM
Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis - The Lancet Public Health www.thelancet.com/journals/lan...
📢Postmenopausal women with CVD have a 31% higher risk of breast cancer with each 5 kg/m² increase in BMI, compared to a 13% increase in those without CVD. #BreastCancer #CVD
🙏 @wcrf.org
👉 doi.org/10.1002/cncr...
🙏 @wcrf.org
👉 doi.org/10.1002/cncr...
July 8, 2025 at 7:25 AM
📢Postmenopausal women with CVD have a 31% higher risk of breast cancer with each 5 kg/m² increase in BMI, compared to a 13% increase in those without CVD. #BreastCancer #CVD
🙏 @wcrf.org
👉 doi.org/10.1002/cncr...
🙏 @wcrf.org
👉 doi.org/10.1002/cncr...
👋 Preprint for comments:
@michaeljstein.bsky.social et al.
#proteomics #physicalActivity #multimorbidity #cancer
www.medrxiv.org/content/10.1...
@michaeljstein.bsky.social et al.
#proteomics #physicalActivity #multimorbidity #cancer
www.medrxiv.org/content/10.1...
Proteomics signature of physical activity and risk of multimorbidity of cancer and cardiometabolic diseases
Background: Cancer, cardiovascular diseases (CVD), and type 2 diabetes (T2D) may co-occur, a condition referred to as multimorbidity. Physical activity is inversely associated with each of these disea...
www.medrxiv.org
March 28, 2025 at 10:00 AM
👋 Preprint for comments:
@michaeljstein.bsky.social et al.
#proteomics #physicalActivity #multimorbidity #cancer
www.medrxiv.org/content/10.1...
@michaeljstein.bsky.social et al.
#proteomics #physicalActivity #multimorbidity #cancer
www.medrxiv.org/content/10.1...
👋Adults with #cancer with a history of #diabetes and/or #cardiovascular diseases have a survival disadvantage compared with those with no history of these comorbidities.
🙏Institut national du cancer (INCa)
bmjmedicine.bmj.com/content/4/1/...
🙏Institut national du cancer (INCa)
bmjmedicine.bmj.com/content/4/1/...
Associations between cardiometabolic comorbidities and mortality in adults with cancer: multinational cohort study
Objective To examine separate and joint associations between pre-existing cardiometabolic comorbidities and all cause and cause specific mortality in adults with cancer.Design Multinational cohort stu...
bmjmedicine.bmj.com
March 26, 2025 at 2:21 PM
👋Adults with #cancer with a history of #diabetes and/or #cardiovascular diseases have a survival disadvantage compared with those with no history of these comorbidities.
🙏Institut national du cancer (INCa)
bmjmedicine.bmj.com/content/4/1/...
🙏Institut national du cancer (INCa)
bmjmedicine.bmj.com/content/4/1/...
March 26, 2025 at 8:24 AM
Food environment and obesity: a systematic review and meta-analysis nutrition.bmj.com/content/7/1/...
Food environment and obesity: a systematic review and meta-analysis
Background Obesity is influenced by a complex, multifaceted system of determinants, including the food environment. Governments need evidence to act on improving the food environment. The aim of this ...
nutrition.bmj.com
March 25, 2025 at 3:24 PM
Food environment and obesity: a systematic review and meta-analysis nutrition.bmj.com/content/7/1/...
📢#Alcohol and #smoking habits in association with #hepatocellularcarcinoma risk 👉
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Alcohol and smoking habits in association with hepatocellular carcinoma risk
Smoking and alcohol consumption are modifiable lifestyle risk factors for hepatocellular carcinoma. While they differentially contribute to DNA damage, proto-oncogene activation, and mitochondrial im....
onlinelibrary.wiley.com
March 23, 2025 at 1:57 PM
📢#Alcohol and #smoking habits in association with #hepatocellularcarcinoma risk 👉
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
👋reminder
⬆️a higher consumption of #nuts is inversely associated with risk of certain #cancers and dying from cancer.
www.mdpi.com/2198962
⬆️a higher consumption of #nuts is inversely associated with risk of certain #cancers and dying from cancer.
www.mdpi.com/2198962
Dried Fruits, Nuts, and Cancer Risk and Survival: A Review of the Evidence and Future Research Directions
Dried fruits and nuts contain high amounts of nutrients and phytochemicals—all of which may have anticarcinogenic, anti-inflammatory, and antioxidant properties. This narrative review summarizes the e...
www.mdpi.com
February 7, 2025 at 4:41 PM
👋reminder
⬆️a higher consumption of #nuts is inversely associated with risk of certain #cancers and dying from cancer.
www.mdpi.com/2198962
⬆️a higher consumption of #nuts is inversely associated with risk of certain #cancers and dying from cancer.
www.mdpi.com/2198962
👋An overdue formal head to head of #RCTs and #cohort studies in #nutrition 👉
👏 Stadelmaier et al.
rdcu.be/d8Zgj
👏 Stadelmaier et al.
rdcu.be/d8Zgj
Evaluating agreement between individual nutrition randomised controlled trials and cohort studies - a meta-epidemiological study | BMC Medicine
rdcu.be
February 7, 2025 at 12:16 PM
👋An overdue formal head to head of #RCTs and #cohort studies in #nutrition 👉
👏 Stadelmaier et al.
rdcu.be/d8Zgj
👏 Stadelmaier et al.
rdcu.be/d8Zgj
How one language family took over the world: ancient DNA traces its spread www.nature.com/articles/d41...
How one language family took over the world: ancient DNA traces its spread
Millennia-old genomes suggest Indo–European tongues originated from the Caucasus mountain region.
www.nature.com
February 7, 2025 at 10:14 AM
How one language family took over the world: ancient DNA traces its spread www.nature.com/articles/d41...
👋 Is your #bodyshape linked to early death?
Bohmann P. @michaeljstein.bsky.social @julian-konzok.bsky.social et al.
@uniregensburg.bsky.social
@dfg.de
👉 journals.lww.com/epidem/abstr...
Bohmann P. @michaeljstein.bsky.social @julian-konzok.bsky.social et al.
@uniregensburg.bsky.social
@dfg.de
👉 journals.lww.com/epidem/abstr...
Body Shapes of Multiple Anthropometric Traits and All-cause ... : Epidemiology
ds:
Using UK Biobank data from 462,301 adults (40–69 years at baseline: 2006–2010), we derived four body shapes from principal component analysis on body mass index, height, weight, waist and hip ci...
journals.lww.com
February 5, 2025 at 5:23 PM
👋 Is your #bodyshape linked to early death?
Bohmann P. @michaeljstein.bsky.social @julian-konzok.bsky.social et al.
@uniregensburg.bsky.social
@dfg.de
👉 journals.lww.com/epidem/abstr...
Bohmann P. @michaeljstein.bsky.social @julian-konzok.bsky.social et al.
@uniregensburg.bsky.social
@dfg.de
👉 journals.lww.com/epidem/abstr...
Nice study highlighting challenges associated with accessibility to the Mediterranean diet, particularly for the most disadvantaged populations. Public policies are suggested to facilitate its wider adoption.
www.mdpi.com/61012
www.mdpi.com/61012
Cost and Cost-Effectiveness of the Mediterranean Diet: Results of a Systematic Review
The growing impact of chronic degenerative pathologies (such as cardiovascular disease, type 2 diabetes and Alzheimer’s disease) requires and pushes towards the development of new preventive strategie...
www.mdpi.com
January 28, 2025 at 12:04 PM
Nice study highlighting challenges associated with accessibility to the Mediterranean diet, particularly for the most disadvantaged populations. Public policies are suggested to facilitate its wider adoption.
www.mdpi.com/61012
www.mdpi.com/61012