Heinz Freisling
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hfreisling.bsky.social
Heinz Freisling
@hfreisling.bsky.social
26 followers 24 following 27 posts
Hi, I am epidemiologist at the International Agency for Research on Cancer. Posts reflect my own opinions and views.
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hfreisling.bsky.social
👉 With Lancet's refined definition of #obesity, we found clinical obesity (excess fat + organ dysfunction) linked to a 56% higher #mortality vs. no obesity.
👉 #BMI alone misses key risks.
@michaeljstein.bsky.social
@uniregensburg.bsky.social
🙏 @wcrf.org
👉 10.1001/jamainternmed.2025.4978
October 28, 2025 at 12:27 PM
hfreisling.bsky.social
Regression adjustment for causal inference bmjmedicine.bmj.com/content/4/1/...
Regression adjustment for causal inference
Causal inference identifies and quantifies the effect of an exposure (the hypothetical cause) to an outcome. While randomised controlled trial design is the preferred method for establishing and measu...
bmjmedicine.bmj.com
October 28, 2025 at 7:48 AM
hfreisling.bsky.social
👋Imaging-derived organ measurements outperform #BMI in predicting risks for #diabetes, #cancer & #mortality.

👉Advanced imaging may redefine how we assess obesity-related health risks. #ObesityResearch

doi.org/10.1186/s129...
Client Challenge
doi.org
October 13, 2025 at 4:53 PM
hfreisling.bsky.social
👋MR analyses (~40K Europeans) showed causal links between specific fat depots and #cancer
👉Liver fat ↑ liver cancer risk
👉Pancreas fat ↑ ovarian cancer risk
👉Abdominal subcutaneous adipose tissue ↑ endometrial ↑ liver, ↑ esophageal, ↑ovarian cancer
@wcrf.org
👉 doi.org/10.1093/jnci...
Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis
AbstractIntroduction. There is convincing evidence that overall adiposity increases the risks of several cancers. Whether the distribution of adiposity pla
doi.org
September 28, 2025 at 12:36 PM
hfreisling.bsky.social
👋Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis - The Lancet Healthy Longevity
#cancer #cvd #diabetes
www.thelancet.com/journals/lan...
Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis
A healthy plant-based diet might reduce the burden of multimorbidity of cancer and cardiometabolic diseases among middle-aged and older adults.
www.thelancet.com
August 21, 2025 at 9:01 AM
hfreisling.bsky.social
Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis - The Lancet Public Health www.thelancet.com/journals/lan...
Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis
Although 10 000 steps per day can still be a viable target for those who are more active, 7000 steps per day is associated with clinically meaningful improvements in health outcomes and might be a mor...
www.thelancet.com
August 19, 2025 at 6:28 AM
hfreisling.bsky.social
📢Postmenopausal women with CVD have a 31% higher risk of breast cancer with each 5 kg/m² increase in BMI, compared to a 13% increase in those without CVD. #BreastCancer #CVD

🙏 @wcrf.org

👉 doi.org/10.1002/cncr...
July 8, 2025 at 7:25 AM
hfreisling.bsky.social
👋 Preprint for comments:
@michaeljstein.bsky.social et al.
#proteomics #physicalActivity #multimorbidity #cancer
www.medrxiv.org/content/10.1...
Proteomics signature of physical activity and risk of multimorbidity of cancer and cardiometabolic diseases
Background: Cancer, cardiovascular diseases (CVD), and type 2 diabetes (T2D) may co-occur, a condition referred to as multimorbidity. Physical activity is inversely associated with each of these disea...
www.medrxiv.org
March 28, 2025 at 10:00 AM
hfreisling.bsky.social
👋Adults with #cancer with a history of #diabetes and/or #cardiovascular diseases have a survival disadvantage compared with those with no history of these comorbidities.

🙏Institut national du cancer (INCa)

bmjmedicine.bmj.com/content/4/1/...
Associations between cardiometabolic comorbidities and mortality in adults with cancer: multinational cohort study
Objective To examine separate and joint associations between pre-existing cardiometabolic comorbidities and all cause and cause specific mortality in adults with cancer.Design Multinational cohort stu...
bmjmedicine.bmj.com
March 26, 2025 at 2:21 PM
hfreisling.bsky.social
@foodwatch-int.bsky.social 👉
March 26, 2025 at 8:24 AM
hfreisling.bsky.social
Food environment and obesity: a systematic review and meta-analysis nutrition.bmj.com/content/7/1/...
Food environment and obesity: a systematic review and meta-analysis
Background Obesity is influenced by a complex, multifaceted system of determinants, including the food environment. Governments need evidence to act on improving the food environment. The aim of this ...
nutrition.bmj.com
March 25, 2025 at 3:24 PM
hfreisling.bsky.social
📢#Alcohol and #smoking habits in association with #hepatocellularcarcinoma risk 👉
onlinelibrary.wiley.com/doi/10.1002/...
Alcohol and smoking habits in association with hepatocellular carcinoma risk
Smoking and alcohol consumption are modifiable lifestyle risk factors for hepatocellular carcinoma. While they differentially contribute to DNA damage, proto-oncogene activation, and mitochondrial im....
onlinelibrary.wiley.com
March 23, 2025 at 1:57 PM
hfreisling.bsky.social
👋reminder
⬆️a higher consumption of #nuts is inversely associated with risk of certain #cancers and dying from cancer.
www.mdpi.com/2198962
Dried Fruits, Nuts, and Cancer Risk and Survival: A Review of the Evidence and Future Research Directions
Dried fruits and nuts contain high amounts of nutrients and phytochemicals—all of which may have anticarcinogenic, anti-inflammatory, and antioxidant properties. This narrative review summarizes the e...
www.mdpi.com
February 7, 2025 at 4:41 PM
hfreisling.bsky.social
👋An overdue formal head to head of #RCTs and #cohort studies in #nutrition 👉
👏 Stadelmaier et al.

rdcu.be/d8Zgj
Evaluating agreement between individual nutrition randomised controlled trials and cohort studies - a meta-epidemiological study | BMC Medicine
rdcu.be
February 7, 2025 at 12:16 PM
hfreisling.bsky.social
How one language family took over the world: ancient DNA traces its spread www.nature.com/articles/d41...
How one language family took over the world: ancient DNA traces its spread
Millennia-old genomes suggest Indo–European tongues originated from the Caucasus mountain region.
www.nature.com
February 7, 2025 at 10:14 AM
hfreisling.bsky.social
www.nature.com/articles/d41...
How are researchers using AI? Survey reveals pros and cons for science
Despite strong interest in using artificial intelligence to make research faster, easier and more accessible, researchers say they need more support to navigate its possibilities.
www.nature.com
February 5, 2025 at 6:40 PM
hfreisling.bsky.social
👋 Is your #bodyshape linked to early death?
Bohmann P. @michaeljstein.bsky.social @julian-konzok.bsky.social et al.
@uniregensburg.bsky.social
@dfg.de
👉 journals.lww.com/epidem/abstr...
Body Shapes of Multiple Anthropometric Traits and All-cause ... : Epidemiology
ds: Using UK Biobank data from 462,301 adults (40–69 years at baseline: 2006–2010), we derived four body shapes from principal component analysis on body mass index, height, weight, waist and hip ci...
journals.lww.com
February 5, 2025 at 5:23 PM
hfreisling.bsky.social
go.nature.com/40BVP1H
World Cancer Day 2025: United by Unique
We are commemorating World Cancer Day by sharing a selection of Springer Nature journal articles, collections, clinical trial registrations and blog posts chosen by our publishers.
go.nature.com
February 4, 2025 at 8:51 AM
hfreisling.bsky.social
Nice study highlighting challenges associated with accessibility to the Mediterranean diet, particularly for the most disadvantaged populations. Public policies are suggested to facilitate its wider adoption.
www.mdpi.com/61012
Cost and Cost-Effectiveness of the Mediterranean Diet: Results of a Systematic Review
The growing impact of chronic degenerative pathologies (such as cardiovascular disease, type 2 diabetes and Alzheimer’s disease) requires and pushes towards the development of new preventive strategie...
www.mdpi.com
January 28, 2025 at 12:04 PM
hfreisling.bsky.social
Both sufficient #physical activity & lean #waist matter for #cancer prevention👉
@michaeljstein.bsky.social @julian-konzok.bsky.social et al
🙏 @wcrf.org
bit.ly/3EbdrKk
WHO guidelines on waist circumference and physical activity and their joint association with cancer risk
Objective Low body fat and high physical activity levels are key lifestyle factors in cancer prevention, but the interplay of abdominal obesity and physical activity on cancer risk remains unknown. We...
bit.ly
January 27, 2025 at 7:38 PM
hfreisling.bsky.social
Hôtel-Dieu, this morning🤩
Lyon, France 🇫🇷
January 27, 2025 at 7:30 PM
hfreisling.bsky.social
📢 Spoiler alert: In #midlife, the environment rather than genetic predisposition driving #Obesity 👉

👏 Dr Laia Peruchet-Noray et al.

🙏 @Institut_cancer

Nature or nurture? sciencedirect.com/science/arti...
December 17, 2024 at 9:34 AM
hfreisling.bsky.social
#Movember at IARC-WHO
Mo Bros and Mo Sisters supporting Men's #Health
December 9, 2024 at 9:07 AM
Reposted by Heinz Freisling
spilleron.bsky.social
That is a super great news 😄
bsky.app Bluesky @bsky.app · Dec 3
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
altmetric.com Altmetric @altmetric.com · Dec 3
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.

A Place of Joy.
December 3, 2024 at 7:53 PM
hfreisling.bsky.social
📢Excess weight by degree and duration and #cancer risk
👏
@NadinHawwash
& colleagues
@eClinicalMed
👉
sciencedirect.com/science/arti...
December 9, 2024 at 8:27 AM