Hendrik Dietz
@hendrikdietz.bsky.social
Very excited that this study led by @erturklab.bsky.social is finally out. Among deep insight into in vivo distribution of LNP and AAV (together with some unexpected effects), it shows how DNA origami nanoparticles distribute in organisms and can be targeted to cells. www.nature.com/articles/s41...
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology
An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.
www.nature.com
January 14, 2025 at 7:49 PM
Very excited that this study led by @erturklab.bsky.social is finally out. Among deep insight into in vivo distribution of LNP and AAV (together with some unexpected effects), it shows how DNA origami nanoparticles distribute in organisms and can be targeted to cells. www.nature.com/articles/s41...
Reposted by Hendrik Dietz
Crosspost from X: After showing that AF2 can be used to design very large proteins by performing #RSO, I am happy to share another fun project we did: the #af2cycler @sokrypton.org @hendrikdietz.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Alphafold2 refinement improves designability of large de novo proteins
Recent advances in computational protein design have enabled the creation of novel proteins for a variety of purposes. The capability for producing custom-shape high-quality backbones for very large p...
www.biorxiv.org
November 22, 2024 at 12:47 PM
Crosspost from X: After showing that AF2 can be used to design very large proteins by performing #RSO, I am happy to share another fun project we did: the #af2cycler @sokrypton.org @hendrikdietz.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...