Hatley Lab
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hatleylab.bsky.social
Hatley Lab
@hatleylab.bsky.social
The Hatley Lab in the Molecular Oncology Division at St. Jude studies how normal development is hijacked in pediatric cancer using rhabdomyosarcoma as a model.
Reposted by Hatley Lab
Proud to share a new paper in Developmental Cell! This project spans over a decade of work and it's been amazing to see it all come together. Huge cheers to Randy, @hatleylab.bsky.social and the rest of the team! www.cell.com/developmenta...
Non-cell-autonomous tumor promotion in DICER1 cancer predisposition
Patients with DICER1 cancer predisposition typically harbor a germline heterozygous inactivating mutation in DICER1. Whether DICER1 mutant non-cancerous cells contribute to tumor promotion was previou...
www.cell.com
September 30, 2025 at 3:00 AM
Non-cell-autonomous tumor promotion in DICER1 cancer predisposition: Developmental Cell www.cell.com/developmenta...
Non-cell-autonomous tumor promotion in DICER1 cancer predisposition
Patients with DICER1 cancer predisposition typically harbor a germline heterozygous inactivating mutation in DICER1. Whether DICER1 mutant non-cancerous cells contribute to tumor promotion was previou...
www.cell.com
September 29, 2025 at 3:06 PM
Transdifferentiation of endothelial progenitor cells into rhabdomyosarcoma defined by hedgehog signaling competence: Cell Reports www.cell.com/cell-reports...
Latest from @hatleylab.bsky.social
Transdifferentiation of endothelial progenitor cells into rhabdomyosarcoma defined by hedgehog signaling competence
Gadek et al. show that embryonal rhabdomyosarcoma formation is defined by the presence of primary cilia and limits SHH pathway competency in early endothelial progenitor cells that disappear during em...
www.cell.com
September 25, 2025 at 1:46 PM
Stellar Hatley grad students took 1st and 2nd place oral presentations at the St. Jude PhD symposium! @stjudegraduate @StJudeResearch
September 17, 2025 at 10:47 PM
Hatley lab grad students represent! Randy Larsen won St Jude Grad School Research Achievement Award and Bradley Stevens with an honorable mention. We appreciate all our great students!
April 11, 2025 at 9:30 PM
Great to be @cedars-sinai.bsky.social meeting with regenerative medicine institute investigators. Terrific group of innovative scientists.
March 26, 2025 at 8:24 PM
Tune in today to the Science of Childhood Cancer series from the St Jude Comprehensive Cancer Center featuring Dr. Martine Roussel. @molonc-stjude.bsky.social www.stjude.org/education-tr...
February 6, 2025 at 3:21 PM