Hassan Fazilaty
@hassanfazilaty.bsky.social
Molecular biologist passionate about the connection between embryonic development and cancer.
Group leader/senior scientist, Department of Gastroenterology and Hepatology, University Hospital Zurich
Group leader/senior scientist, Department of Gastroenterology and Hepatology, University Hospital Zurich
Pinned
An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer
Reactivated embryonic programs are associated with cancer progression, yet their role and regulatory mechanisms remain poorly understood. In this study, we introduce ‘oncoembryology,’ an approach that...
www.biorxiv.org
Hello friends!
Thrilled to join the Bluesky community! My research delves into the connections between embryonic development and cancer, using a novel approach we call 'oncoembryology'.
Check out our latest preprint: www.biorxiv.org/content/10.1...
And our review: www.nature.com/articles/s41...
Thrilled to join the Bluesky community! My research delves into the connections between embryonic development and cancer, using a novel approach we call 'oncoembryology'.
Check out our latest preprint: www.biorxiv.org/content/10.1...
And our review: www.nature.com/articles/s41...
Reposted by Hassan Fazilaty
🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.
October 7, 2025 at 11:57 AM
🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.
Looking for a PhD student in cancer biology.
Project: Oncoembryology – targeting reactivated embryonic programs in cancer.
Application via Life Science Zurich Graduate School
Deadline: 1 Nov 2025.
👉 Full details here: www.linkedin.com/posts/hassan...
#PhD #CancerBiology #Oncoembryology #Zurich
Project: Oncoembryology – targeting reactivated embryonic programs in cancer.
Application via Life Science Zurich Graduate School
Deadline: 1 Nov 2025.
👉 Full details here: www.linkedin.com/posts/hassan...
#PhD #CancerBiology #Oncoembryology #Zurich
Application | Hassan Fazilaty
PhD Position in Cancer Biology — Oncoembryology (USZ, Zurich)
In my upcoming position at Department of Gastroenterology and Hepatology, University Hospital Zurich (USZ), I am looking for a motivated ...
www.linkedin.com
September 9, 2025 at 4:42 PM
Looking for a PhD student in cancer biology.
Project: Oncoembryology – targeting reactivated embryonic programs in cancer.
Application via Life Science Zurich Graduate School
Deadline: 1 Nov 2025.
👉 Full details here: www.linkedin.com/posts/hassan...
#PhD #CancerBiology #Oncoembryology #Zurich
Project: Oncoembryology – targeting reactivated embryonic programs in cancer.
Application via Life Science Zurich Graduate School
Deadline: 1 Nov 2025.
👉 Full details here: www.linkedin.com/posts/hassan...
#PhD #CancerBiology #Oncoembryology #Zurich
It is time to view cancer as “wounds that do not heal”, and act accordingly!
In this short piece with Tosca Dalessi, we explore how oncoembryonic programs could reshape precision therapy:
— Less collateral damage
— Prevent resistance
— Better models for discovery
🔗 doi.org/10.1002/ctm2...
In this short piece with Tosca Dalessi, we explore how oncoembryonic programs could reshape precision therapy:
— Less collateral damage
— Prevent resistance
— Better models for discovery
🔗 doi.org/10.1002/ctm2...
Unlocking oncoembryonic programs for clinical advances in cancer therapy
Click on the article title to read more.
doi.org
July 14, 2025 at 10:32 AM
It is time to view cancer as “wounds that do not heal”, and act accordingly!
In this short piece with Tosca Dalessi, we explore how oncoembryonic programs could reshape precision therapy:
— Less collateral damage
— Prevent resistance
— Better models for discovery
🔗 doi.org/10.1002/ctm2...
In this short piece with Tosca Dalessi, we explore how oncoembryonic programs could reshape precision therapy:
— Less collateral damage
— Prevent resistance
— Better models for discovery
🔗 doi.org/10.1002/ctm2...
Reposted by Hassan Fazilaty
#Postdoc position alert 🚨My friend and colleague Iros Barozzi is offering a fully funded postdoc postion studying tumor heterogeneity using functional genomics 🧬 and single cell omics 🧑🔬. great lab and great collaborators :) join our institute in beautiful Vienna.
June 17, 2025 at 7:50 AM
#Postdoc position alert 🚨My friend and colleague Iros Barozzi is offering a fully funded postdoc postion studying tumor heterogeneity using functional genomics 🧬 and single cell omics 🧑🔬. great lab and great collaborators :) join our institute in beautiful Vienna.
Kudos to Cammareri and co. of Myant lab for unveiling how ATRX & HNF4A gatekeep colonic identity—lose ATRX, and cells go rogue, fueling CRC metastasis. A crucial step toward understanding and targeting plasticity in #ColorectalCancer! #CancerResearch
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Loss of colonic fidelity enables multilineage plasticity and metastasis - Nature
The chromatin-remodelling enzyme ATRX and the transcription factor HNF4A are identified as pivotal regulators of colonic epithelial identity, with roles in metastasis in colorectal cancer.
www.nature.com
June 5, 2025 at 11:05 AM
Kudos to Cammareri and co. of Myant lab for unveiling how ATRX & HNF4A gatekeep colonic identity—lose ATRX, and cells go rogue, fueling CRC metastasis. A crucial step toward understanding and targeting plasticity in #ColorectalCancer! #CancerResearch
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Hassan Fazilaty
Move beyond ‘publish or perish’ by measuring behaviours that benefit academia
Perspective in #Nature 🧪 suggesting a new "G+ index" — G representing generosity, giving and other ‘good things’ in academia
Wouldn't this be great 🤔
By Prof. Kelly-Ann Allen
www.nature.com/articles/d41...
Perspective in #Nature 🧪 suggesting a new "G+ index" — G representing generosity, giving and other ‘good things’ in academia
Wouldn't this be great 🤔
By Prof. Kelly-Ann Allen
www.nature.com/articles/d41...
February 26, 2025 at 4:46 PM
Move beyond ‘publish or perish’ by measuring behaviours that benefit academia
Perspective in #Nature 🧪 suggesting a new "G+ index" — G representing generosity, giving and other ‘good things’ in academia
Wouldn't this be great 🤔
By Prof. Kelly-Ann Allen
www.nature.com/articles/d41...
Perspective in #Nature 🧪 suggesting a new "G+ index" — G representing generosity, giving and other ‘good things’ in academia
Wouldn't this be great 🤔
By Prof. Kelly-Ann Allen
www.nature.com/articles/d41...
By 2030, 1 in 3 colorectal cancers will occur before age 50! The speed at which early-onset colorectal cancer metastasizes remains unclear, but understanding its biology is urgent to prevent a looming cancer epidemic.
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Tumor “age” in early-onset colorectal cancer
The incidence of early-onset colorectal cancer (EO-CRC) is surging, and by 2030, one-third
of all CRCs will occur before the commonly recommended screening age of 50 years.
The time required for EO-CR...
www.cell.com
February 7, 2025 at 9:20 AM
By 2030, 1 in 3 colorectal cancers will occur before age 50! The speed at which early-onset colorectal cancer metastasizes remains unclear, but understanding its biology is urgent to prevent a looming cancer epidemic.
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Today is #WorldCancerDay, a day to reflect and push for progress.
Cancer affects millions, but research and innovative treatments are changing lives. Every discovery, every breakthrough, and every act of support brings us closer to a future where cancer is no longer a life-threatening disease.
Cancer affects millions, but research and innovative treatments are changing lives. Every discovery, every breakthrough, and every act of support brings us closer to a future where cancer is no longer a life-threatening disease.
February 4, 2025 at 3:37 PM
Today is #WorldCancerDay, a day to reflect and push for progress.
Cancer affects millions, but research and innovative treatments are changing lives. Every discovery, every breakthrough, and every act of support brings us closer to a future where cancer is no longer a life-threatening disease.
Cancer affects millions, but research and innovative treatments are changing lives. Every discovery, every breakthrough, and every act of support brings us closer to a future where cancer is no longer a life-threatening disease.
Congratulations Bahar and team!
First Preprint from BD lab!🚀
I’m beyond excited to share our ENS-Rich Assembloids (ERAs) - a breakthrough tool for studying the Enteric Nervous System (ENS)!🔬🧫 @ilkesari.bsky.social @belizuzun.bsky.social @t-valenta.bsky.social
Check it out biorxiv.org/cgi/content/...
I’m beyond excited to share our ENS-Rich Assembloids (ERAs) - a breakthrough tool for studying the Enteric Nervous System (ENS)!🔬🧫 @ilkesari.bsky.social @belizuzun.bsky.social @t-valenta.bsky.social
Check it out biorxiv.org/cgi/content/...
January 15, 2025 at 6:38 PM
Congratulations Bahar and team!
Exciting new findings reveal eosinophils as key allies in the fight against colorectal cancer by blocking tumor spread.
Great work by Kristina Handler, Deeksha Raju, Alessandra Gurtner & team lead by the amazing Isabelle Arnold! Honored to be a part of this study.
www.biorxiv.org/content/10.1...
Great work by Kristina Handler, Deeksha Raju, Alessandra Gurtner & team lead by the amazing Isabelle Arnold! Honored to be a part of this study.
www.biorxiv.org/content/10.1...
Eosinophils restrict CRC metastasis by inhibiting pro-tumorigenic SPP1+ macrophage differentiation
Eosinophils, traditionally associated with allergic responses, have emerged as critical immune modulators in colorectal cancer (CRC). Here, we reveal that eosinophils actively shape the tumor microenv...
www.biorxiv.org
December 18, 2024 at 4:23 PM
Exciting new findings reveal eosinophils as key allies in the fight against colorectal cancer by blocking tumor spread.
Great work by Kristina Handler, Deeksha Raju, Alessandra Gurtner & team lead by the amazing Isabelle Arnold! Honored to be a part of this study.
www.biorxiv.org/content/10.1...
Great work by Kristina Handler, Deeksha Raju, Alessandra Gurtner & team lead by the amazing Isabelle Arnold! Honored to be a part of this study.
www.biorxiv.org/content/10.1...
Reposted by Hassan Fazilaty
Honored that our story on Plexin B2 was mentioned alongside these amazing studies! 🥰
aacrjournals.org/cancerdiscov...
aacrjournals.org/cancerdiscov...
Reflections on Advances in Cancer Research in 2024
There have been many impactful advances in basic, translational, and clinical cancer research in 2024. An important mission of Cancer Discovery is to ensure the timely dissemination of innovative ways...
aacrjournals.org
December 2, 2024 at 10:43 PM
Honored that our story on Plexin B2 was mentioned alongside these amazing studies! 🥰
aacrjournals.org/cancerdiscov...
aacrjournals.org/cancerdiscov...
Reposted by Hassan Fazilaty
A growth, and then a metastasis, of cancer researchers (two starter packs)...
by @johannajoyce.bsky.social
bsky.app/starter-pack...
bsky.app/starter-pack...
by @johannajoyce.bsky.social
bsky.app/starter-pack...
bsky.app/starter-pack...
November 23, 2024 at 12:06 PM
A growth, and then a metastasis, of cancer researchers (two starter packs)...
by @johannajoyce.bsky.social
bsky.app/starter-pack...
bsky.app/starter-pack...
by @johannajoyce.bsky.social
bsky.app/starter-pack...
bsky.app/starter-pack...
Hello friends!
Thrilled to join the Bluesky community! My research delves into the connections between embryonic development and cancer, using a novel approach we call 'oncoembryology'.
Check out our latest preprint: www.biorxiv.org/content/10.1...
And our review: www.nature.com/articles/s41...
Thrilled to join the Bluesky community! My research delves into the connections between embryonic development and cancer, using a novel approach we call 'oncoembryology'.
Check out our latest preprint: www.biorxiv.org/content/10.1...
And our review: www.nature.com/articles/s41...
An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer
Reactivated embryonic programs are associated with cancer progression, yet their role and regulatory mechanisms remain poorly understood. In this study, we introduce ‘oncoembryology,’ an approach that...
www.biorxiv.org
November 18, 2024 at 1:23 PM
Hello friends!
Thrilled to join the Bluesky community! My research delves into the connections between embryonic development and cancer, using a novel approach we call 'oncoembryology'.
Check out our latest preprint: www.biorxiv.org/content/10.1...
And our review: www.nature.com/articles/s41...
Thrilled to join the Bluesky community! My research delves into the connections between embryonic development and cancer, using a novel approach we call 'oncoembryology'.
Check out our latest preprint: www.biorxiv.org/content/10.1...
And our review: www.nature.com/articles/s41...