Govind Persad
govindpersad.bsky.social
Govind Persad
@govindpersad.bsky.social

Law professor, University of Colorado Law School. Teach and research on health law and bioethics. Papers, etc: https://sites.google.com/site/govindpersad

Economics 40%
Public Health 32%

Reposted by Govind Persad

Reposted by Govind Persad

Reposted by Govind Persad

Reposted by Govind Persad

Reposted by Govind Persad

"Fair Allocation of GLP-1 and Dual GLP-1–GIP Receptor Agonists" is now out in NEJM (w/Zeke Emanuel, Johan Dellgren, Matt McCoy).

We propose a #bioethics framework to guide gov'ts, professional societies, & docs in allocation choices about drugs like semaglutide (Ozempic/Wegovy) when demand > supply
Fair Allocation of GLP-1 and Dual GLP-1–GIP Receptor Agonists | NEJM
A shortage of GLP-1 receptor agonists and other drugs raises questions about how limited supplies should be allocated. A proposed framework could guide governments, professional societies, and ...
www.nejm.org

Reposted by Govind Persad

Reposted by Govind Persad

Reposted by Govind Persad

www.wsj.com/articles/for...

See if this is unlocked and works

Last, while trade-offs in drug spending are inevitable, a creative strategy--#Pigouvian taxes--could lessen their sharpness

States could raise revenues for covering GLP-1s, while mitigating the need for them, by taxing sodas and other obesogenic foods
Cities with soda taxes saw sales of sugary drinks fall as prices rose, study finds
Soda taxes are meant to discourage people from drinking too much sugar, which is linked to a host of bad health outcomes. Cities that imposed the taxes saw a 33% decrease in the sale of sugary drinks.
www.npr.org

Instead, we must honestly and fairly consider trade-offs.

States need to compare drugs- including across different medical conditions- based on value, not just refuse to cover later-arriving drugs like GLP-1s

Value comparisons can help negotiate prices & create incentives for effective drugs

4/5
Value-Based Pricing of Prescription Drugs Benefits Patients and Promotes Innovation
Value-based pricing aligns prescription drug prices to their clinical benefits, leading to lower spending and better health outcomes.
www.americanprogress.org

Would the House's proposed ban on cost-effectiveness analysis (CEA) techniques improve GLP-1 access?

No. It will make things worse.

CEA bans make refusals to cover GLP-1s, like NC’s, that only consider cost & unethically ignore value for money more likely, not less

#bioethics

3/5
The much-maligned ‘quality-adjusted life year’ is a vital tool for health care policy
A new bill that would ban government use of quality-adjusted life years is misguided.
www.statnews.com

Blanket refusal to cover GLP-1s for obesity is wrong because GLP-1s are more cost-effective than many other drugs North Carolina covers.

States made the same mistake when they initially refused to pay for new Hepatitis C drugs

2/5
Hepatitis C can be cured. So why aren't more people getting treatment?
A new CDC report finds that just a third of those diagnosed with hepatitis C have cleared the virus — a decade after a cure was made available.
www.npr.org
North Carolina & other health systems are being unethical when they categorically refuse to cover GLP-1 receptor agonists (e.g. Ozempic, Mounjaro) for obesity.

So I & Zeke Emanuel argue in our Wall Street Journal op-ed.

I highlight some of our points below in replies

#bioethics
Opinion | For Obese Patients, Wegovy Is Worth the Cost
North Carolina is wrong to deny coverage. Breakthrough treatments curb additional health risks.
wsj.com

I mostly know ethics/political ones: Crooked Timber, PEA Soup, and lots of defunct ones (Public Reason, Ethics Etc, my personal fave Left2Right).

I was so looking forward to posting to Public Reason when I finished my PhD, but instead we just have social media

This piece made me think about how structural problems with fragmentation of support programs exacerbate disadvantage, even though the piece sometimes took a frustratingly “blame the hospital” lens.

Would’ve loved to hear more in the piece about reforms that would help undo this fragmentation

Reposted by Govind Persad

…of a paper that determines my judgement of the paper. But the assumptions and starting points of the argument should be reasonable to anyone. In that sense I can offer a fair review of a paper even if the conclusion is something that I deeply disagree with.

Reposted by Govind Persad

No, I think value judgements are inevitable, even in the sciences ppl make (epistemic) value judgements all the time - though often implicitly. On top of that It seems impossible to do (and review in) ethics in a morally neutral way. But it should not be my own moral perspective on the conclusion…

Some of the litigation I discuss that challenges consideration of race in health grantmaking is patterned on litigation against non-health grantmakers (e.g. Atlanta's Fearless Fund) being brought by the same organization and attorneys that litigated the Harvard/UNC affirmative action cases
Venture capital fund defends grants for Black women in US appeals court
A venture capital fund on Wednesday urged a U.S. appeals court to allow it to resume a grant program that awards funding to businesses run by Black women and reject an anti-affirmative action group's claim that it discriminates based on race.
www.reuters.com

Revised draft of “Antiracist Medicine in Colorblind Courts,” forthcoming in the Michigan Law Review papers.ssrn.com/sol3/papers....

Added material on new §1981, §1557, & Equal Protection litigation against health & other programs that consider individuals’ race

New TX & UT laws are also discussed

Leah Rand & @akesselheim.bsky.social have a couple of nice papers explaining the problems with QALY bans and evaluating ethical critiques of cost-effectiveness analysis:

"Congress’ Misguided Plan to Ban QALYs" (JAMA)

Review of ethical critiques of QALYs: www.healthaffairs.org/doi/abs/10.1...
Congress’s Misguided Plan to Ban QALYs
This Viewpoint discusses the flawed assumptions and potential negative impacts of a proposed federal bill that would ban government health care programs from us
jamanetwork.com

QALYs are an imperfect measure of the value of a drug

But often (certainly w/Congress' QALY ban) critics aren't suggesting a better alternative--they want the US, unlike everywhere else, to pay for drugs without measuring or comparing their value

Result: no accountability for pharma, just $$$

Thanks to the University of Denver's #RadioEd podcast for featuring my research on healthcare affordability!

I analyze health affordability in depth in my "Defining Health Affordability," published (open access) in the Iowa Law Review: ilr.law.uiowa.edu/volume-109-i...

#healthlaw #bioethics
What Makes American Healthcare (Un)affordable? | University of Denver
University of Denver
www.du.edu

I was today years old when I learned that Philippa Foot (of trolley problem/virtue ethics fame) was Grover Cleveland’s granddaughter

Just listened to interesting Philosophy Bites on transformative experience. Do people really think decisions about whether to become a parent are arational, as opposed to just characterized by imperfect info & value change?

Imperfect info, likelihood of change in values ≠ arationality.

I listened to your episode over the holidays! Really enjoyed hearing more about ways of measuring potential benefits of #IRB .

The Biounethical podcast with Sophie Gibert & @leahpierson.bsky.social has been great listening material for my New Year’s resolution to walk more.

Just finished episode w/Danielle Allen on #bioethics & public participation & now in the middle of one with Jeff Sebo on the circle of moral concern