The functionalization of GaAs, a model III-V semiconductor, with N-heterocyclic carbenes is demonstrated in a multidisciplinary experimental and theoretical approach. In this way, ordered monolayers ...

𝗕𝘂𝗻𝗱𝗲𝘀𝗸𝗮𝗻𝘇𝗹𝗲𝗿 𝗙𝗿𝗶𝗲𝗱𝗿𝗶𝗰𝗵 𝗠𝗲𝗿𝘇 𝘇𝘂 𝗚𝗮𝘀𝘁 𝗯𝗲𝗶 𝗱𝗲𝗿 𝗙𝗿𝗮𝘂𝗻𝗵𝗼𝗳𝗲𝗿 𝗙𝗙𝗕 𝗶𝗻 𝗠ü𝗻𝘀𝘁𝗲𝗿 Ein herzliches Willkommen in der #BatteryCityMünster! Im Rahmen seines Antrittsbesuchs in #NRW besuchte heute Bundeskanzler Frie...

N-Heterocyclic olefins (NHOs), possessing highly polarizable electron-rich double bonds, have recently received increased attention as promising ligands to modify the properties of various surfaces su...

Visible-light-mediated energy transfer (EnT) photocatalysis has emerged as a highly appealing strategy for converting planar (hetero)arenes into complex, medicinally relevant, three-dimensional (3D) architectures. Current methodologies for intermolecular dearomative photocycloadditions, however, are restricted to bicyclic (hetero)aromatic systems, while the more abundant monocyclic (hetero)arenes remain vastly underexplored. Accessing the triplet state of the ubiquitous monocyclic (hetero)arenes poses a formidable challenge due to their high triplet energy barriers. Herein, we report several EnT-catalyzed intermolecular dearomative cycloadditions of monocyclic heteroarenes with alkenes and bicyclo[1.1.0]butanes. To overcome the intrinsic limitations in triplet-state reactivity and accelerate reaction discovery, we introduced a data-driven three-layer screening strategy that integrates predictive data science tools for mapping excited-state properties with luminescence quenching and reaction-based screening. This synergistic three-layer screening strategy uncovers structure-reactivity relationships between substituted monocyclic heteroarenes and biradical acceptors, facilitating the accelerated discovery of new reactivity. Utilizing this data-driven approach, we developed the EnT-catalyzed intermolecular dearomative cycloaddition of thiophenes, oxazoles, and thiazoles with alkenes/bicyclo[1.1.0]butanes, providing access to unprecedented C(sp3)-rich 3D molecular scaffolds.

📣 Postdoc call: Ready to bring AI into the lab? The Glorius Group is calling for a passionate postdoc who wants to shape the future of digital chemistry – where ML models, mass spectrometry, and huma...