The Institute for Glial Sciences
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The Institute for Glial Sciences
@glialsciences.bsky.social
34 followers 21 following 24 posts
Our Mission:

To uncover the mechanisms of glial development and dysfunction and develop breakthrough therapeutic interventions for neurological disease.
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glialsciences.bsky.social
Excited to welcome Bruce Trapp of Cleveland Clinic (tag) as our plenary speaker for next week’s #TGS2025 conference! .
A global leader in #Glia research, his work has redefined how we study and treat neurodegeneration in #MultipleSclerosis.

#TGS2025
🧠 Info & free registration: bit.ly/4qEf1bs
October 29, 2025 at 5:00 PM
glialsciences.bsky.social
The 2025 Translational Glial Sciences Conference agenda is live!

🧠 Nov 4 | 12–6 PM | CWRU Campus, Cleveland
Join leading scientists exploring glia in disease & therapy.
Free registration — space is limited: bit.ly/4qEf1bs
#Glia #TGS2025 #IGS
October 24, 2025 at 12:54 PM
glialsciences.bsky.social
Keynote alert! Lorenz Studer, MD (MSKCC), will speak at #TGS2025 on Nov 4 at the Sheila and Eric Samson Pavilion, Health Ed Campus of CWRU & Cleveland Clinic.

🔗 Learn more and register for free:
case.edu/medicine/gli...
October 20, 2025 at 6:25 PM
glialsciences.bsky.social
🧠 The first Translational Glial Sciences Conference is happening Nov 4 at CWRU.

Discover cutting-edge glial research and therapeutic innovation.

🔗 Learn more + register: case.edu/medicine/gli...

#glialscience #neuro #TGS2025 #CWRU #IGS
October 13, 2025 at 5:29 PM
glialsciences.bsky.social
Dr. Ty Miller is pushing the boundaries of brain tumor immunotherapy at CWRU + UH. His lab explores how to reprogram immune cells into cancer-fighting allies. Proud to have him as an IGS Affiliate. Learn more: tymillerlab.org
October 9, 2025 at 12:03 PM
glialsciences.bsky.social
Congrats to Rania Ziar, PhD student in the Tesar Lab, named a 2025 HHMI Gilliam Fellow! With support from her advisor, Paul Tesar, Rania was recognized for advancing inclusive excellence in science at CWRU.

🔗 bit.ly/4g0AyWQ
Medicine’s Rania Ziar and Paul Tesar named to HHMI Gilliam Fellows Program’s 2025 cohort | CWRU Newsroom | Case Western Reserve University
bit.ly
August 29, 2025 at 7:33 PM
glialsciences.bsky.social
CWRU has now featured the latest research from the Tesar Lab at IGS in the university’s Newsroom. The article highlights how a newly identified molecular “brake” could help treat MS by promoting brain cell maturation.
🔗 Read more: case.edu/news/molecul...
#Neuroscience #MultipleSclerosis #IGS #CWRU
Molecular ‘brake’ in brain development could hold key to treating multiple sclerosis | CWRU Newsroom | Case Western Reserve University
case.edu
August 27, 2025 at 4:55 PM
glialsciences.bsky.social
New work from the Tesar Lab @ IGS identifies a molecular “brake” on brain cell maturation—offering a path to repair in MS.

📰 News: www.eurekalert.org/news-release...
📄 Paper: www.cell.com/cell/abstrac...

#Neuroscience #GlialScience #MultipleSclerosis #IGS #CWRU
Molecular ‘brake’ in brain development could hold key to treating multiple sclerosis
A team of scientists led by the Institute for Glial Sciences (IGS) at Case Western Reserve University’s School of Medicine has discovered a built-in “brake” that controls when key br...
www.eurekalert.org
August 26, 2025 at 1:26 PM
glialsciences.bsky.social
Thrilled to share that Dr. Marissa Scavuzzo, IGS faculty at CWRU, has been awarded a 2024 Hartwell Award. Her innovative work explores how glial cells in the gut may influence autism—using stem cell–based “mini-guts” to reveal new insights.
🔗 Read more: bit.ly/46M8uUA
Case Western Reserve University researcher earns prestigious Individual Biomedical Research Award from The Hartwell Foundation to explore gut-brain link in autism
Up to 70% of children with autism spectrum disorder (ASD) experience chronic digestive issues—and Case Western Reserve University School of Medicine’s Marissa Scavuzzo wants to not only understand why...
bit.ly
August 7, 2025 at 2:20 PM
glialsciences.bsky.social
IGS grad student Ying Xiong has been awarded an NIH F31 fellowship! His research explores how inflammation impacts oligodendrocyte development—glial cells that are essential in understanding neurodegenerative diseases. #GlialScience #Neuroscience #NIH #F31
August 4, 2025 at 5:43 PM
glialsciences.bsky.social
Meet Kat, our Computational Biology Manager at IGS. From IT to bioinformatics, she’s advanced stem cell work at Gladstone and now drives glial research at CWRU. Vital to our genomic data & lab ops. Off the clock: gardening, stargazing, painting.
#GlialScience #Bioinformatics
July 3, 2025 at 3:03 PM
glialsciences.bsky.social
June is #BrainAwarenessMonth—and June 21 was #GlobalALSAwarenessDay.
At IGS @ CWRU, Dr. Ben Clayton’s lab is reprogramming astrocytes to fight ALS, Alzheimer’s & more.
Read more in The Daily: bit.ly/43XBarT
#GlialScience #Neuroscience #CWRU
Meet a researcher unraveling the mysteries of brain cells to combat neurological diseases
Benjamin Clayton Assistant Professor, Department of Genetics and Genome Sciences, School of MedicineFaculty member of the Institute for Glial Sciences Area of Focus: Glial Cells Research  Ben Clayton ...
thedaily.case.edu
June 24, 2025 at 1:45 PM
glialsciences.bsky.social
On #WorldMSDay, we at IGS highlight a story from @CaseDaily featuring research from IGS and its collaborators on the role of glial cells in multiple sclerosis.

🧠 Read it here: thedaily.case.edu/human-stem-c...

#MSAwareness #IGS #Neuroscience
Human stem cell models point to glia as key players in multiple sclerosis
Largest collection of patient stem cell models of multiple sclerosis to date uncovers novel disease insights and opens the door for new treatments A team of scientists from The New York Stem Cell Foun...
thedaily.case.edu
May 30, 2025 at 5:27 PM
glialsciences.bsky.social
🎓 Huge congrats to the IGS Spring 2025 grads: Bruce Armstrong, Kristin Lee, Arul Mehta, Jeyashri Rameshbabu, Naya Alsouss & Dr. Will Wulftange! Your passion for glial science is the future. 📸
#IGS #Graduation2025 #Neuroscience
May 23, 2025 at 9:17 PM
glialsciences.bsky.social
A huge congratulations to Will on his successful Ph.D. defense! 🎓

His dissertation on microengineered systems for hematological precision therapies explores how immune cells interact with CNS glia—vital work in precision medicine.

We’re proud of you, Will!

#PhDDefense #GlialScience
March 28, 2025 at 5:27 PM
glialsciences.bsky.social
🚨 New Grant for Brain Organoid Research 🚨

The PMD Foundation is funding brain organoid research at CWRU, led by Dr. Paul Tesar (IGS Director) & Dr. Mayur Madhavan to study PMD & leukodystrophies.

🔗 Read more: www.pmdfoundation.org/blog/2025-gr...

#GlialScience #PMD #BrainOrganoids #Neuroscience
2025 Grant Announcement — PMD Foundation
The PMD Foundation is excited to share a new grant that will support brain organoid research at Case Western Reserve University School of Medicine, led by Dr. Paul Tesar and Dr. Mayur Madhavan.
www.pmdfoundation.org
February 20, 2025 at 4:21 PM
glialsciences.bsky.social
Spotlight: Ben Clayton earned his biology degree at Utah and his PhD at UChicago, studying glial cell injury. He developed a screening platform for astrocyte pathology at CWRU. He received a Career Transition Award from the National MS Society and is now an Assistant Professor at CWRU & part of IGS
February 11, 2025 at 5:35 PM
glialsciences.bsky.social
IGS graduate student Ying presented his research at CWRU, examining how inflammation affects oligodendrocytes—work that could help advance MS therapies.

These presentations give students valuable experience and spark insightful discussions. Well done, Ying!

#Neuroscience #MSResearch #CWRU
February 5, 2025 at 7:23 PM
glialsciences.bsky.social
Staff Spotlight: Meet Nicole Datko, our Research Ops Manager! She joined IGS last August with a decade of Cleveland biotech experience and a Biotech degree from Kent State. Outside work, Nicole loves hiking, concerts, and her dog, Bucky.
January 20, 2025 at 3:54 PM
glialsciences.bsky.social
Welcome back, Students! 🎓✨
This year at the Institute for Glial Sciences, we’re diving into new discoveries, building connections, and advancing glial cell research. Your work drives the future of neuroscience—let’s make it a year to remember! #ScienceForward
January 14, 2025 at 9:43 PM
glialsciences.bsky.social
✨ Happy Holidays from the Institute for Glial Sciences! 🧠❄️ We loved celebrating the season with our amazing members and their families. 💙 Laughter, good food, and community made it a perfect way to close the year. Here’s to science, discovery, and togetherness!
December 26, 2024 at 4:07 PM
glialsciences.bsky.social
Member Spotlight: Meet Marissa Scavuzzo, Ph.D. PI at the Institute for Glial Sciences & HHMI Hanna H. Gray Fellow! She studies how glial cells impact gut health. Co-founder of Rise Up: Northeast Ohio, she loves hiking, art, & Lake Erie. Learn more: scavuzzolab.org
December 12, 2024 at 6:12 PM
glialsciences.bsky.social
Meet Dr. Paul Tesar, Director of the Institute for Glial Sciences!

Paul leads pioneering research into glial cells, advancing human health through innovation while mentoring the next generation of scientists.

🔗 Learn more: tesarlab.com/about
About Paul
About Paul TesarThe Dr. Donald and Ruth Weber Goodman Professor of Innovative Therapeutics Director, Institute for Glial Sciences Case Western Reserve University School of Medicine Department of Genet...
tesarlab.com
December 5, 2024 at 4:36 PM
glialsciences.bsky.social
What Are Glial Cells?
Glial cells, or glia (from "glue"), make up 50% of brain cells, holding the nervous system together and playing key roles:

Support: Neuron structure.
Nutrients: Oxygen/supply.
Myelination: Signal insulation.
Homeostasis: Balance.
Immune: Brain defense.
November 27, 2024 at 8:18 PM