Wei et al. show that a ketogenic diet protects against sepsis-induced lung injury via a gut-lung axis. Specific gut lactobacilli convert dietary oleic acid into azelaic acid, which translocates to the...

Rapid advances in microbiome science have sparked clinical and commercial enthusiasm for interventions, yet translation into practice risks outpacing …

The Horizon Awards recognise individuals and teams at the forefront of microbiological research.

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The vaginal mycobiome, though a minor component of the cervicovaginal ecosystem, plays a crucial role in reproductive health and disease. However, its composition and interactions with bacterial communities remain poorly understood, particularly among Hispanic women, who experience disproportionately high rates of Human papillomavirus (HPV) infection and cervical cancer. We characterized the vaginal mycobiota across reproductive stages and examined its associations with cervical disease, HPV status, and bacterial community state types (CSTs) in 86 Hispanic participants from Puerto Rico using ITS1 amplicon sequencing. Amplicon sequence variants were inferred with QIIME2/DADA2 and taxonomically classified using the UNITE database, with diversity and discriminant taxa analyses applied to explore clinical and microbial associations. We detected 173 fungal Species Hypotheses, dominated by Candida albicans , Agaricomycetes sp., Scopuloides dimorpha , and Hortaea werneckii . While fungal composition did not differ significantly by reproductive stage, non-pregnant individuals exhibited greater inter-individual variability. Alpha diversity was reduced in high-grade squamous intraepithelial lesions compared with low-grade or normal cytology, and Candida parapsilosis prevalence was elevated in low-grade lesions. CST III, characterized by Lactobacillus iners dominance, showed greater dispersion variance than other CSTs. Collectively, these findings reveal a diverse vaginal mycobiome with stage- and disease-specific features, and a notable contribution of environmental fungi that may influence cervical pathogenesis. This work provides foundational insight into cervicovaginal fungal ecology in a high-risk Hispanic population and highlights the importance of integrating bacteriome–mycobiome analyses in women’s health research.

Introduction Obesity, high blood glucose and high blood pressure are major drivers of global morbidity. Characterising temporal trends in these conditions among people of African origin can direct pub...

This Review summarizes recent and compelling examples of microbiome-based interventions that are ripe for clinical adoption while also discussing the challenges and opportunities facing the field.

Experts across UC San Diego have united to launch the Soil Health Center at Scripps Institution of Oceanography. Established in fall 2025, the center brings together an interdisciplinary team that’s d...

Microbes make up about 99% of all species, but they’re not part of any global conservation plans. One group is trying to change that.

A quiet policy change means the government is making fewer bets on long-term science.

Microbes make up about 99% of all species, but they’re not part of any global conservation plans. One group is trying to change that.

Abstract. As the first and dominant life forms on the planet, microorganisms underpin all ecological and organismal systems that drive planetary functionin

A new paper outlines how scientists came together to put together the first microbial conservation roadmap under the leadership of Applied Microbiology International President, Professor Jack Gilbert.

Abstract. As the first and dominant life forms on the planet, microorganisms underpin all ecological and organismal systems that drive planetary functionin

UC San Diego has once again been recognized among the top institutions in the world on the 2025 Highly Cited Researchers list compiled by Clarivate. UC San Diego tied for 18th in the world this year w...