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Gastroenterology Advisor
@gastroadvisor.bsky.social
Trusted knowledge base of practical information and resources focused on gastroenterology medicine.
In both sexes, visceral adipose tissue volume, muscle adipose tissue infiltration, and liver fat fraction were strongest predictors of #cardiovascular age.

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Shared, Sex-Specific Body Fat Patterns Linked to Cardiovascular Aging
Visceral adipose tissue volume, muscle adipose tissue infiltration, and liver fat fraction predicted cardiovascular age.
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December 22, 2025 at 5:47 PM
Older adults (aged 65 years and older) with #overweight who undergo elective surgery have a lower rate of 30-day all-cause mortality compared with those with a normal #BMI.

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December 21, 2025 at 5:28 PM
Managing metabolic dysfunction-associated steatotic liver disease may help prevent irritable bowel syndrome. #MASLD

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MASLD Paired With Cardiometabolic Risk Factors Linked to High Risk for IBS
Metabolic dysfunction-associated steatotic liver disease is associated with an increased risk for incident irritable bowel syndrome.
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December 20, 2025 at 6:10 PM
A science advisory regarding the association between ultra-processed foods and #cardiometabolic health has been published by the @AHA.

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AHA Targets Ultra-Processed Foods and Cardiometabolic Health in Science Advisory
A science advisory has been published by the AHA regarding the association between ultra-processed foods and cardiometabolic health.
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December 20, 2025 at 2:20 AM
Improvements in #cardiometabolic risk factors were also seen in patients treated with #orforglipron.

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Orforglipron Reduces Body Weight, A1C in Adults With Obesity and T2D
Topline data were announced from a phase 3 trial evaluating orforglipron, an oral GLP-1 receptor agonist, in adults with obesity or overweight and T2D.
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December 18, 2025 at 6:25 PM
About two-thirds of reproductive-aged women in the United States have preexisting modifiable risk factors for birth defects. #birthdefect

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Many Women Have Preexisting Modifiable Risk Factors for Birth Defects
Most nonpregnant, nonlactating women of reproductive age reported at least one known modifiable risk factor for birth defects.
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December 17, 2025 at 5:21 PM
Maternal use of #cephalosporins or #antibiotics was associated with a small increased risk for #Crohn disease, and antibiotic exposure in certain infant groups was associated with a modestly increased risk for autoimmune thyroiditis.

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Antibiotics in Pregnancy, Infancy Not Linked to Autoimmune Diseases
No association was seen between antibiotic exposure during pregnancy or early infancy and overall incidence of autoimmune diseases.
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December 16, 2025 at 5:38 PM
Combining energy reduction and physical exercise with the #MedDiet reduced 6-year #diabetes incidence by 2.6 cases per 1000 person-years compared with MedDiet alone.

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MedDiet Plus Energy Reduction, Physical Activity Reduces Incidence of Type 2 Diabetes
Lower diabetes incidence and bigger loss in weight and waist circumference were seen with combined energy reduction, MedDiet, and exercise.
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December 15, 2025 at 5:27 PM
#AI-drafted clinical notes from clinician-patient conversations reduced reported physician burnout and improved perceived documentation-related well-being.

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December 14, 2025 at 5:08 PM
After age 50, childhood #cancer survivors have a “considerably higher” risk of death than what is expected in the general population, researchers found.

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Childhood Cancer Survivors Have Higher Risk of New Cancers, Death After Age 50
Childhood cancer survivors have an increased risk of premature death and developing new cancers and other health conditions after age 50, data suggest.
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December 13, 2025 at 6:21 PM
#AI may not improve the optical diagnosis of #gastric malignancies.

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Can AI-Assisted Endoscopy Improve Optical Diagnosis of Gastric Neoplasia?
Computer-aided diagnosis does not improve the optical diagnosis of gastric neoplasia in nonexpert endoscopists.
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December 12, 2025 at 5:58 PM
DPYD/UGT1A1 testing before treatment with a fluoropyrimidine or irinotecan can reduce the risk of serious #TRAEs in patients with #gastrointestinal cancers.

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DPYD/UGT1A1 Testing May Decrease Risk of TRAEs in Gastrointestinal Cancer Patients
DPYD/UGT1A1 testing before treatment with a fluoropyrimidine or irinotecan can reduce the risk of serious TRAEs in patients with gastrointestinal cancers, data suggest.
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December 11, 2025 at 6:18 PM
The incidence rate of inflammatory bowel disease-related outcomes was 11.9 and 15.1 per 100 person-years among patients with #IBD and #obesity who did and did not undergo bariatric surgery, respectively.

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Bariatric Surgery Linked to Improved IBD Outcomes in Patients With Obesity
Bariatric surgery was linked to reduction in IBD-related outcomes in patients with inflammatory bowel disease and obesity.
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December 10, 2025 at 5:15 PM
It is important for clinicians to weigh the benefit vs risk of treatment with corticosteroids among patients with #UC.

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What Effect Do Corticosteroids Have on Risk for Adverse Events in UC?
Corticosteroid use is associated with adverse events in clinical trials studying ulcerative colitis.
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December 9, 2025 at 5:45 PM
Rates of intestinal parasitic infections run high among individuals with colorectal cancer. #CRC

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Intestinal Parasitic Infections Increase Risk, Progression of Colorectal Cancer
Individuals with colorectal cancer have a high prevalence of parasitic infections, including helminths and protozoa.
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December 8, 2025 at 5:25 PM
#Methotrexate intolerance was observed among 34.5% of the study cohort with rheumatoid arthritis. #RA

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Methotrexate Intolerance Affects a Significant Percentage of Patients With RA
Results of a cross-sectional study in India showed that a significant percentage of adults with RA are intolerant to MTX.
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December 7, 2025 at 5:33 PM
The Signos Glucose Monitoring System is a mobile device application that receives data from an OTC integrated continuous #glucose monitor, the Dexcom Stelo Biosenor.

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FDA-Cleared App Plus Over-the-Counter CGM Now Available for Weight Management
Signos Inc. has announced the availability of the Signos Glucose Monitoring System for weight management.
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December 6, 2025 at 6:02 PM
Women with #cirrhosis and ascites experience worse health-related quality of life (HRQoL) than men.

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Worse Emotional Health-Related QOL Seen for Women With Cirrhosis, Ascites
Women with cirrhosis and ascites experienced worse mental health and more frequent depression than equivalent men.
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December 6, 2025 at 2:45 AM
#CKD risk was reduced in association with greater adherence to Dietary Approaches to Stop Hypertension and the Dietary Inflammatory Index.

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Dietary Patterns Linked to Chronic Kidney Disease Risk
Dietary Approaches to Stop Hypertension and the Dietary Inflammatory Index are associated with lower CKD risk.
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December 4, 2025 at 5:57 PM
Patients with #IBD seldom use self-help resources, although most patients believe they are feasible and acceptable

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Self-Help Resources Infrequently Used by Patients With IBD
Few individuals with IBD use self-help resources, although resources are acceptable and feasible to 75% of patients.
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December 3, 2025 at 5:45 PM
Acid suppression may not be beneficial among patients with simple #esophageal atresia/tracheoesophageal fistula.

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Infants May Benefit From Acid Suppression After Esophageal Atresia Repair
Incidence of strictures may be lower among some infants with complex esophageal atresia/tracheoesophageal fistula (EA/TEF) repair who receive postoperative acid suppression.
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December 2, 2025 at 5:25 PM
According to Accord BioPharma, #Imuldosa prefilled syringes will be available at a 92% discount to Stelara and at a 33% discount for the vial formulation.

Read More: https://www.gastroenterologyadvisor.com/news/ustekinumab-biosimilar-imuldosa-now-available/
December 1, 2025 at 4:26 PM
Work-related income decreased 6.6% and 1.6% for mothers and fathers, respectively, in the year after their child's type 1 #diabetes diagnosis.

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Work-Related Income Drops for Parents of Children Diagnosed With Type 1 Diabetes
Work-related income mothers and fathers of children with type 1 diabetes decreased in the year after diagnosis.
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November 30, 2025 at 5:35 PM
Participants with #MetS were 1.39 times more likely to develop #Parkinson disease vs those without MetS.

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Metabolic Syndrome Linked to Increased Risk for Parkinson Disease
Increased risk for Parkinson disease was seen for participants with metabolic syndrome and high PD-related polygenic risk score.
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November 29, 2025 at 5:00 AM
Participants with #MetS were 1.39 times more likely to develop #Parkinson disease vs those without MetS.

Read More: https://www.gastroenterologyadvisor.com/news/metabolic-syndrome-linked-to-increased-risk-for-parkinson-disease/
November 28, 2025 at 5:00 AM