Francois Lebreton
@flebreton.bsky.social
Director of bioinformatics at WRAIR-MRSN. Interests in microbial genomics, antimicrobial resistance and bacterial evolution.
Reposted by Francois Lebreton
Cumulative cgMLST : Our novel preprint is out @biorxiv doi.org/10.1101/2025...
Cumulative cgMLST provides increased discrimination of nested phylogenetic groups
Background Core genome multilocus sequence typing (cgMLST) is a powerful method for bacterial strain genotyping. However, the size of the core genome decreases as the phylogenetic breadth of the targe...
doi.org
November 26, 2025 at 2:27 PM
Cumulative cgMLST : Our novel preprint is out @biorxiv doi.org/10.1101/2025...
New preprint out! Anjali Sapre, Melissa Martin and co. mapped the evolutionary routes of convergence in K pneumo. Pop analysis of >1,400 global genomes & 7,500 closed plasmids to see how #AMR & virulence genes come together and impact phenotypes. www.researchsquare.com/article/rs-8...
Preferred evolutionary routes of convergence in Klebsiella pneumoniae favor siderophore acquisition over hypervirulence
The rise of Klebsiella pneumoniae combining antimicrobial resistance and virulence genes poses a major health threat, but the evolutionary routes and phenotypic consequences of this convergence are po...
www.researchsquare.com
February 18, 2026 at 8:28 PM
New preprint out! Anjali Sapre, Melissa Martin and co. mapped the evolutionary routes of convergence in K pneumo. Pop analysis of >1,400 global genomes & 7,500 closed plasmids to see how #AMR & virulence genes come together and impact phenotypes. www.researchsquare.com/article/rs-8...
Reposted by Francois Lebreton
Please visit: www.icarecourse.org
@ICARe_AMR has a great atmosphere and location @LesPensieres , with a unique faculty and a special session on #AMR #genomics with François Lebreton @flebreton.bsky.social and myself – great opportunities for networking and scientific discussions
@ICARe_AMR has a great atmosphere and location @LesPensieres , with a unique faculty and a special session on #AMR #genomics with François Lebreton @flebreton.bsky.social and myself – great opportunities for networking and scientific discussions
April 17, 2025 at 4:56 PM
Please visit: www.icarecourse.org
@ICARe_AMR has a great atmosphere and location @LesPensieres , with a unique faculty and a special session on #AMR #genomics with François Lebreton @flebreton.bsky.social and myself – great opportunities for networking and scientific discussions
@ICARe_AMR has a great atmosphere and location @LesPensieres , with a unique faculty and a special session on #AMR #genomics with François Lebreton @flebreton.bsky.social and myself – great opportunities for networking and scientific discussions
Reposted by Francois Lebreton
New postdoc position in our lab (2 y+): evolutionary genomics of integrons and MGEs with focus on vibrio-phage interactions. Great environment @pasteur.fr for science, career building. Super collaborators @celineloot.bsky.social @amazeld.bsky.social @fredoleroux.bsky.social 3 weeks to apply!
April 16, 2025 at 7:14 AM
New postdoc position in our lab (2 y+): evolutionary genomics of integrons and MGEs with focus on vibrio-phage interactions. Great environment @pasteur.fr for science, career building. Super collaborators @celineloot.bsky.social @amazeld.bsky.social @fredoleroux.bsky.social 3 weeks to apply!