Farnaby Research Group
farnabygroup.bsky.social
Farnaby Research Group
@farnabygroup.bsky.social
Chemical innovation for CNS diseases
Reposted by Farnaby Research Group
New preprint out co-led Nur Kocaturk along with colleagues at University of Dundee and Bio-Techne showing a direct-to-biology discovery of a brain penetrant degrader of GSK3. Congratulations to all!
chemrxiv.org/engage/chemr...
Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screening
Bifunctional targeted protein degraders, also known as Proteolysis Targeting Chimeras (PROTACs), are an emerging drug modality that may offer a new approach to understand and treat neurodegenerative d...
chemrxiv.org
March 10, 2025 at 2:00 PM
Excited to share the Farnaby Group’s first pre-print, detailing our approach to plate-based bifunctional chemical probe discovery, identifying a brain active PROTAC directly from a single screen. 1/7

chemrxiv.org/engage/chemr...
Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screening
Bifunctional targeted protein degraders, also known as Proteolysis Targeting Chimeras (PROTACs), are an emerging drug modality that may offer a new approach to understand and treat neurodegenerative d...
chemrxiv.org
March 10, 2025 at 12:52 PM
We have a new fully funded PhD position in the lab. Looking forward to finding excellent talents to work with! Check out the link for more info ⤵️.

www.dundee.ac.uk/phds/opportu...
A chemical toolbox to investigate protein-protein interactions and their impact on mitophagy signalling - EASTBIO | University of Dundee, UK
A PhD project at the University of Dundee
www.dundee.ac.uk
December 11, 2024 at 11:27 AM
Farnaby research group is on BlueSky now. Keep following our group updates!
December 5, 2024 at 8:06 PM