Ian Bosdet
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exon.bsky.social
Ian Bosdet
@exon.bsky.social
Geneticist @BCCancer, Associate Professor @UBC, mediocre photographer, soccer dad, data science hobbyist. I've had all my shots. Opinions are barely even mine.
MRD (minimal/measurable/molecular residual disease) is a staple of #hematologic #cancer testing. We use sensitive assays to detect #tumour #DNA in the blood, for treatment response monitoring and relapse prediction. Soon we'll be doing this for solid tumours too. www.nature.com/articles/s41...
Minimal residual disease as a target for liquid biopsy in patients with solid tumours - Nature Reviews Clinical Oncology
Liquid biopsy, or the analysis of tumour-derived or tumour-induced cells or cellular products in the blood or other body fluids, is a promising approach to assess minimal residual disease (MRD; also k...
www.nature.com
December 2, 2024 at 11:54 PM
Are you #CCMG and/or #ABMGG certified and considering a move to beautiful Vancouver? Come join my team at BC Cancer! We do germline and somatic testing across a wide range of solid and hematologic cancers using some of the latest molecular and cytogenetic technologies. jobs.phsa.ca/job/vancouve...
Clinical Laboratory Geneticist Cancer Genetics & Genomics Laboratory Department of Pathology and Laboratory Medicine - BC Cancer - Vancouver at PHSA
Learn more about applying for Clinical Laboratory Geneticist Cancer Genetics & Genomics Laboratory Department of Pathology and Laboratory Medicine - BC Cancer - Vancouver at PHSA
jobs.phsa.ca
November 11, 2024 at 7:28 PM
Whole-genome sequencing in a large cohort of paediatric patients has a 9% secondary finding rate. My lab is just now transitioning our adult germline testing to a WGS backbone, and peds is coming soon, so I’m reading this with interest and some trepidation.

www.gimjournal.org/article/S109...
Secondary ACMG and non-ACMG genetic findings in a multiethnic cohort of 16,713 pediatric participants
Clinical next-generation sequencing is an effective approach for identifying pathogenic sequence variants that are medically actionable for participants and families but are not associated with the pa...
www.gimjournal.org
November 11, 2024 at 7:08 PM
They shall grow not old,
as we that are left grow old: 
Age shall not weary them,
nor the years condemn.
At the going down of the sun
and in the morning
We will remember them.
—Lawrence Binyon

#RemembranceDay2024
November 11, 2024 at 7:00 PM