European Journal of Neurology
@europeanjournalofneurology.ean.org
The official Journal of the European Academy of Neurology. Covers all areas of clinical and basic research in neurology. #EurJNeurol #OpenAccess
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🌙🧠 Zhou et al. suggest that glymphatic function measured with DTI-ALPS (Diffusion tensor image analysis along the perivascular space) links Cerebral Small Vessel Disease burden and sleep quality to cognitive decline.
📚 onlinelibrary.wiley.com/doi/10.1111/...
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📚 onlinelibrary.wiley.com/doi/10.1111/...
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November 18, 2025 at 3:03 PM
🌙🧠 Zhou et al. suggest that glymphatic function measured with DTI-ALPS (Diffusion tensor image analysis along the perivascular space) links Cerebral Small Vessel Disease burden and sleep quality to cognitive decline.
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Sleep
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Sleep
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➖ Bjelica et al. show that in adult 5q-SMA on nusinersen treatment, CMAP amplitudes remained stable.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #SMA
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#Neurology #SMA
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November 15, 2025 at 10:01 AM
➖ Bjelica et al. show that in adult 5q-SMA on nusinersen treatment, CMAP amplitudes remained stable.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #SMA
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #SMA
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🦷 Camps-Plomer et al. report a significant association between periodontitis and migraine in Association Between Migraine and Periodontitis: A Systematic Review and Meta-Analysis.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Migraine
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Migraine
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November 13, 2025 at 3:04 PM
🦷 Camps-Plomer et al. report a significant association between periodontitis and migraine in Association Between Migraine and Periodontitis: A Systematic Review and Meta-Analysis.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Migraine
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Migraine
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🧫 Obara et al. conclude that NfL is the most validated ALS biomarker in blood and CSF. They warn that single marker use risks misclassification and recommend multimodal approaches.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #NfL #ALS
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #NfL #ALS
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November 11, 2025 at 3:04 PM
🧫 Obara et al. conclude that NfL is the most validated ALS biomarker in blood and CSF. They warn that single marker use risks misclassification and recommend multimodal approaches.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #NfL #ALS
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #NfL #ALS
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💡 Shimada and Ishikawa et al. find that greater trapezius stiffness aligns with worse TTH severity. Weakness and heavy eyelid sensation may be useful clinical clues.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache
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November 8, 2025 at 10:00 AM
💡 Shimada and Ishikawa et al. find that greater trapezius stiffness aligns with worse TTH severity. Weakness and heavy eyelid sensation may be useful clinical clues.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache
@ean.org #WileyNeuro
Check out the October issue of European Journal of Neurology!
📚 Read now: onlinelibrary.wiley.com/toc/14681331...
#EurJNeurol #Neurology #EJoN
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📚 Read now: onlinelibrary.wiley.com/toc/14681331...
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October 31, 2025 at 9:02 AM
Check out the October issue of European Journal of Neurology!
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💡 Søborg et al. demonstrate that PACAP-38 levels are elevated across all cluster headache states, supporting PACAP as a therapeutic target while noting no clear correlation with CGRP.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #PACAP #ClusterHeadache
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #PACAP #ClusterHeadache
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October 28, 2025 at 3:05 PM
💡 Søborg et al. demonstrate that PACAP-38 levels are elevated across all cluster headache states, supporting PACAP as a therapeutic target while noting no clear correlation with CGRP.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #PACAP #ClusterHeadache
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #PACAP #ClusterHeadache
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🗣️ Hossain et al. show that shorter disease duration associates with behavioral dyscontrol, frontal lobe involvement, and higher 4-repeat tau burden in the locus coeruleus.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Apraxia
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Apraxia
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October 25, 2025 at 10:02 AM
🗣️ Hossain et al. show that shorter disease duration associates with behavioral dyscontrol, frontal lobe involvement, and higher 4-repeat tau burden in the locus coeruleus.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Apraxia
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Apraxia
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🩺 Doneddu et al. demonstrate that incorporating additional electrophysiological parameters improves diagnostic sensitivity without compromising specificity, expanding the recognized spectrum of MMN abnormalities.
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Neuropathy
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📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Neuropathy
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October 23, 2025 at 3:05 PM
🩺 Doneddu et al. demonstrate that incorporating additional electrophysiological parameters improves diagnostic sensitivity without compromising specificity, expanding the recognized spectrum of MMN abnormalities.
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Neuropathy
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Neuropathy
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⚡ Chemaly & Kuchenbuch et al. show that CBD reduces seizures and improves comorbidities, with strong 18-month retention supporting its efficacy and tolerability beyond approved indications.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Epilepsy
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#Neurology #Epilepsy
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October 21, 2025 at 3:00 PM
⚡ Chemaly & Kuchenbuch et al. show that CBD reduces seizures and improves comorbidities, with strong 18-month retention supporting its efficacy and tolerability beyond approved indications.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Epilepsy
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Epilepsy
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❤️ Galea et al. find that LAAC is safe and feasible, with lower recurrent stroke rates than continued OAC alone, suggesting additive protection pending confirmation from randomized trials.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Stroke
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#Neurology #Stroke
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October 18, 2025 at 9:02 AM
❤️ Galea et al. find that LAAC is safe and feasible, with lower recurrent stroke rates than continued OAC alone, suggesting additive protection pending confirmation from randomized trials.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Stroke
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Stroke
@ean.org #WileyNeuro
🧠 Caestecker et al. review in “The Locus Coeruleus–Noradrenergic System in the Healthy and Diseased Brain” how integrating anatomical, neurochemical, and functional data clarifies the LCNA system’s central role and therapeutic potential
📚 onlinelibrary.wiley.com/doi/10.1111/...
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📚 onlinelibrary.wiley.com/doi/10.1111/...
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October 16, 2025 at 3:45 PM
🧠 Caestecker et al. review in “The Locus Coeruleus–Noradrenergic System in the Healthy and Diseased Brain” how integrating anatomical, neurochemical, and functional data clarifies the LCNA system’s central role and therapeutic potential
📚 onlinelibrary.wiley.com/doi/10.1111/...
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
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💪 Popkirov reports in that reduced grip strength reflects altered higher-order motor control, challenging its value as a biomarker of peripheral dysfunction.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MECFS
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#Neurology #MECFS
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October 14, 2025 at 4:05 PM
💪 Popkirov reports in that reduced grip strength reflects altered higher-order motor control, challenging its value as a biomarker of peripheral dysfunction.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MECFS
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MECFS
@ean.org #WileyNeuro
🧩 Marini et al. show in that the insular knife-cut sign on MRI strongly predicts HSVE and should raise immediate suspicion even when other tests are inconclusive.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
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October 12, 2025 at 9:00 AM
🧩 Marini et al. show in that the insular knife-cut sign on MRI strongly predicts HSVE and should raise immediate suspicion even when other tests are inconclusive.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
@ean.org #WileyNeuro
🧪 Hegen et al. demonstrate that the κ-FLC index closely aligns with OCB, with discordant results mainly in the gray zone. A reflex testing approach using κ-FLC first and OCB for gray-zone cases appears reasonable.
📚 onlinelibrary.wiley.com/doi/full/10....
#Neuroimmunology
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📚 onlinelibrary.wiley.com/doi/full/10....
#Neuroimmunology
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October 10, 2025 at 3:05 PM
🧪 Hegen et al. demonstrate that the κ-FLC index closely aligns with OCB, with discordant results mainly in the gray zone. A reflex testing approach using κ-FLC first and OCB for gray-zone cases appears reasonable.
📚 onlinelibrary.wiley.com/doi/full/10....
#Neuroimmunology
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/full/10....
#Neuroimmunology
@ean.org #WileyNeuro
Check out the September issue of European Journal of Neurology!
📚 Read now: onlinelibrary.wiley.com/toc/14681331...
#EurJNeurol #Neurology #EJoN
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/toc/14681331...
#EurJNeurol #Neurology #EJoN
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September 30, 2025 at 4:07 PM
Check out the September issue of European Journal of Neurology!
📚 Read now: onlinelibrary.wiley.com/toc/14681331...
#EurJNeurol #Neurology #EJoN
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/toc/14681331...
#EurJNeurol #Neurology #EJoN
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Betancourt et al. demonstrate in 7 Tesla MRI in Multiple Sclerosis: Insights From Its Use in Clinical Routine that 7T MRI increases diagnostic certainty in challenging MS cases, with potential impact on care decisions.
📚 onlinelibrary.wiley.com/doi/10.1111/...
#MS #MRI
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📚 onlinelibrary.wiley.com/doi/10.1111/...
#MS #MRI
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September 29, 2025 at 3:05 PM
Betancourt et al. demonstrate in 7 Tesla MRI in Multiple Sclerosis: Insights From Its Use in Clinical Routine that 7T MRI increases diagnostic certainty in challenging MS cases, with potential impact on care decisions.
📚 onlinelibrary.wiley.com/doi/10.1111/...
#MS #MRI
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
#MS #MRI
@ean.org #WileyNeuro
Gilboa & Hanuka et al. show that early EEGs support diagnosis while later EEGs better predict recurrence, both complementing each other in care.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #EEG #Seizure
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #EEG #Seizure
@ean.org #WileyNeuro
September 28, 2025 at 11:17 AM
Gilboa & Hanuka et al. show that early EEGs support diagnosis while later EEGs better predict recurrence, both complementing each other in care.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #EEG #Seizure
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #EEG #Seizure
@ean.org #WileyNeuro
Jungilligens et al. reveal that Functional Neurological Disorder is the third most common inpatient diagnosis, yet remains underrepresented in training, services, and funding
📚 Functional Neurological Disorder Among Neurology In-Patients onlinelibrary.wiley.com/doi/10.1111/...
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📚 Functional Neurological Disorder Among Neurology In-Patients onlinelibrary.wiley.com/doi/10.1111/...
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September 26, 2025 at 3:15 PM
Jungilligens et al. reveal that Functional Neurological Disorder is the third most common inpatient diagnosis, yet remains underrepresented in training, services, and funding
📚 Functional Neurological Disorder Among Neurology In-Patients onlinelibrary.wiley.com/doi/10.1111/...
@ean.org #WileyNeuro
📚 Functional Neurological Disorder Among Neurology In-Patients onlinelibrary.wiley.com/doi/10.1111/...
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Chen et al. report in “Efficacy and Safety of Twelve Anti-Dyskinetic Drugs in Parkinson's Disease” that amantadine ER is more effective than IR for dyskinesia, and both reduce OFF time better than other drugs.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology
@ean.org #WileyNeuro
September 23, 2025 at 4:14 PM
Chen et al. report in “Efficacy and Safety of Twelve Anti-Dyskinetic Drugs in Parkinson's Disease” that amantadine ER is more effective than IR for dyskinesia, and both reduce OFF time better than other drugs.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology
@ean.org #WileyNeuro
Argyriou et al. find that migraine worsens after discontinuation and early effectiveness is reduced upon re-initiation, challenging mandated CGRP pauses.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache #CGRP
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache #CGRP
@ean.org #WileyNeuro
September 21, 2025 at 11:11 AM
Argyriou et al. find that migraine worsens after discontinuation and early effectiveness is reduced upon re-initiation, challenging mandated CGRP pauses.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache #CGRP
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache #CGRP
@ean.org #WileyNeuro
🌟 Want to strengthen your career in research?
Discover skills to peer review with impact, support editors & authors, and advance your career 🚀
Take the course “All you need to know to become an effective peer reviewer” for free: www.wileyresearcheracademy.com/l/pdp/all-yo...
@ean.org #WileyNeuro
Discover skills to peer review with impact, support editors & authors, and advance your career 🚀
Take the course “All you need to know to become an effective peer reviewer” for free: www.wileyresearcheracademy.com/l/pdp/all-yo...
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September 17, 2025 at 11:19 AM
🌟 Want to strengthen your career in research?
Discover skills to peer review with impact, support editors & authors, and advance your career 🚀
Take the course “All you need to know to become an effective peer reviewer” for free: www.wileyresearcheracademy.com/l/pdp/all-yo...
@ean.org #WileyNeuro
Discover skills to peer review with impact, support editors & authors, and advance your career 🚀
Take the course “All you need to know to become an effective peer reviewer” for free: www.wileyresearcheracademy.com/l/pdp/all-yo...
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Min et al. suggest that stricter thresholds for grip strength may improve diagnostic specificity and reliability in clinical monitoring of CIDP.
📚 Minimal Clinically Important Difference for the Jamar Hand Grip Dynamometer in CIDP onlinelibrary.wiley.com/doi/10.1111/...
#CIDP
@ean.org #WileyNeuro
📚 Minimal Clinically Important Difference for the Jamar Hand Grip Dynamometer in CIDP onlinelibrary.wiley.com/doi/10.1111/...
#CIDP
@ean.org #WileyNeuro
September 15, 2025 at 4:10 PM
Min et al. suggest that stricter thresholds for grip strength may improve diagnostic specificity and reliability in clinical monitoring of CIDP.
📚 Minimal Clinically Important Difference for the Jamar Hand Grip Dynamometer in CIDP onlinelibrary.wiley.com/doi/10.1111/...
#CIDP
@ean.org #WileyNeuro
📚 Minimal Clinically Important Difference for the Jamar Hand Grip Dynamometer in CIDP onlinelibrary.wiley.com/doi/10.1111/...
#CIDP
@ean.org #WileyNeuro
In Psychological Variables Mediate Symptoms in Persistent Postural-Perceptual Dizziness, Sereda et al. show that cognitive appraisals such as perceived injustice strongly shape #PPPD symptoms.
📚 onlinelibrary.wiley.com/doi/10.1111/...
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
@ean.org #WileyNeuro
September 13, 2025 at 2:04 PM
In Psychological Variables Mediate Symptoms in Persistent Postural-Perceptual Dizziness, Sereda et al. show that cognitive appraisals such as perceived injustice strongly shape #PPPD symptoms.
📚 onlinelibrary.wiley.com/doi/10.1111/...
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
@ean.org #WileyNeuro
Tepper et al. report in "Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache that Erenumab" sustained remission and functional improvement for one year, with safety consistent with prior trials
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology
@ean.org #WileyNeuro
September 11, 2025 at 4:06 PM
Tepper et al. report in "Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache that Erenumab" sustained remission and functional improvement for one year, with safety consistent with prior trials
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology
@ean.org #WileyNeuro