Eswarappa Lab IISc
@eswarappalab.bsky.social
Traversing through the regulation of translation at its start & stop and looking into teeny-tiny tardigrades. PI: Sandeep M Eswarappa | Indian Institute of Science Bangalore
Lab website: https://sites.google.com/view/dr-sandeep-m-eswarappa/home?authuser=0
Lab website: https://sites.google.com/view/dr-sandeep-m-eswarappa/home?authuser=0
Reposted by Eswarappa Lab IISc
How short can a degron be?
A compact, genetically encoded, 9-aa tunable degron that drives MDM2-dependent degradation enabling precise control of protein levels from yeast to human cells.
Thanks to @eswarappalab.bsky.social for the opportunity to explore this in yeast.
#Degron #Yeast #CellBiology 🧬
A compact, genetically encoded, 9-aa tunable degron that drives MDM2-dependent degradation enabling precise control of protein levels from yeast to human cells.
Thanks to @eswarappalab.bsky.social for the opportunity to explore this in yeast.
#Degron #Yeast #CellBiology 🧬
February 12, 2026 at 10:17 AM
How short can a degron be?
A compact, genetically encoded, 9-aa tunable degron that drives MDM2-dependent degradation enabling precise control of protein levels from yeast to human cells.
Thanks to @eswarappalab.bsky.social for the opportunity to explore this in yeast.
#Degron #Yeast #CellBiology 🧬
A compact, genetically encoded, 9-aa tunable degron that drives MDM2-dependent degradation enabling precise control of protein levels from yeast to human cells.
Thanks to @eswarappalab.bsky.social for the opportunity to explore this in yeast.
#Degron #Yeast #CellBiology 🧬
Interested in tunable protein degradation? Check out our new preprint describing a compact, portable degron derived from MTCH2: doi.org/10.64898/202...
Led by Lekha EM
Saubhik Som
Ramon Boro
Sandeep Eswarappa
Great collaboration w/ Anubhav Dhar
Eepsitha
@syncellbiolab.bsky.social
#iiscbangalore
Led by Lekha EM
Saubhik Som
Ramon Boro
Sandeep Eswarappa
Great collaboration w/ Anubhav Dhar
Eepsitha
@syncellbiolab.bsky.social
#iiscbangalore
February 12, 2026 at 10:06 AM
Interested in tunable protein degradation? Check out our new preprint describing a compact, portable degron derived from MTCH2: doi.org/10.64898/202...
Led by Lekha EM
Saubhik Som
Ramon Boro
Sandeep Eswarappa
Great collaboration w/ Anubhav Dhar
Eepsitha
@syncellbiolab.bsky.social
#iiscbangalore
Led by Lekha EM
Saubhik Som
Ramon Boro
Sandeep Eswarappa
Great collaboration w/ Anubhav Dhar
Eepsitha
@syncellbiolab.bsky.social
#iiscbangalore