Esashi Lab
@esashilab.bsky.social
Sir William Dunn School, University of Oxford, Interested in genome stability, homologous recombination, chromosome, centromeres
https://esashilab.wordpress.com/
https://esashilab.wordpress.com/
Absolutely fascinating work! 🔥 The more you think, the more intrigued. We featured it in our highlight 🔗 rdcu.be/eyOGc - such a cool twist in the host–virus warfare. Many congrats to @manellab.bsky.social
August 2, 2025 at 8:07 AM
Absolutely fascinating work! 🔥 The more you think, the more intrigued. We featured it in our highlight 🔗 rdcu.be/eyOGc - such a cool twist in the host–virus warfare. Many congrats to @manellab.bsky.social
We are delighted to share our latest work, characterising the role of BRCA2 and its binding partner PALB2 at centromeres, just out in the latest issue of Cell Reports. ⬇️
www.cell.com/cell-reports...
www.cell.com/cell-reports...
The homologous recombination factors BRCA2 and PALB2 interplay with mismatch repair pathways to maintain centromere stability and cell viability
Graham et al. demonstrate that BRCA2 and PALB2 protect centromere integrity in non-cancerous
cells through distinct mechanisms, partly counteracting the mismatch repair factor
MLH1. In cancer cells, B...
www.cell.com
February 25, 2025 at 5:56 PM
We are delighted to share our latest work, characterising the role of BRCA2 and its binding partner PALB2 at centromeres, just out in the latest issue of Cell Reports. ⬇️
www.cell.com/cell-reports...
www.cell.com/cell-reports...