Mario Emilio Ernesto Franco
@ernestofranco.bsky.social
🧬🧉⚡ fiat lux (he/him)
Reposted by Mario Emilio Ernesto Franco
📣 Now announcing the journal publication 📄 of our work in @newphyt.bsky.social on how Verticillium undermines the plant's 🌱 "cry for help": terrific work by @antonkraege.bsky.social & @wolki95.bsky.social doi.org/10.1111/nph....
Undermining the cry for help: the phytopathogenic fungus Verticillium dahliae secretes an antimicrobial effector protein to undermine host recruitment of antagonistic Pseudomonas bacteria
During pathogen attack, plants recruit beneficial microbes in a ‘cry for help’ to mitigate disease development. Simultaneously, pathogens secrete effectors to promote host colonisation through vario...
doi.org
October 30, 2025 at 8:47 AM
📣 Now announcing the journal publication 📄 of our work in @newphyt.bsky.social on how Verticillium undermines the plant's 🌱 "cry for help": terrific work by @antonkraege.bsky.social & @wolki95.bsky.social doi.org/10.1111/nph....
Reposted by Mario Emilio Ernesto Franco
I'm super excited that our photo of Xylaria was selected for the cover of the August issue of #mSystems! journals.asm.org/toc/msystems...
This complements our recent article on the secondary metabolism of xylarialean fungi (Franco et al., 2025 vol. 10, e00468-25). @ernestofranco.bsky.social
This complements our recent article on the secondary metabolism of xylarialean fungi (Franco et al., 2025 vol. 10, e00468-25). @ernestofranco.bsky.social
August 20, 2025 at 5:15 AM
I'm super excited that our photo of Xylaria was selected for the cover of the August issue of #mSystems! journals.asm.org/toc/msystems...
This complements our recent article on the secondary metabolism of xylarialean fungi (Franco et al., 2025 vol. 10, e00468-25). @ernestofranco.bsky.social
This complements our recent article on the secondary metabolism of xylarialean fungi (Franco et al., 2025 vol. 10, e00468-25). @ernestofranco.bsky.social
Reposted by Mario Emilio Ernesto Franco
Excited to have our paper out in #mSystems. Pairwise co-cultures of only 7 xylarialean strains yielded >6k unique metabolites vs. 2k from monocultures. High richness reflects an abundance of interaction-specific metabolites. Work led by @ernestofranco.bsky.social
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi | mSystems
Saprotrophic and endophytic xylarialean fungi are among the most prolific producers
of bioactive secondary metabolites, with numerous industrial uses as antibiotics,
pharmaceuticals, and insecticidal ...
journals.asm.org
June 9, 2025 at 9:20 PM
Excited to have our paper out in #mSystems. Pairwise co-cultures of only 7 xylarialean strains yielded >6k unique metabolites vs. 2k from monocultures. High richness reflects an abundance of interaction-specific metabolites. Work led by @ernestofranco.bsky.social
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Our new preprint is out! A genomic and metagenomic dive into the diversity of microbial carbonic anhydrases. Huge thanks to the amazing team who made this possible!
@you-wren.bsky.social @laurameredith.bsky.social
www.biorxiv.org/content/10.1...
@you-wren.bsky.social @laurameredith.bsky.social
www.biorxiv.org/content/10.1...
Genomic and metagenomic survey of microbial carbonic anhydrase genes reveals novel clades, high diversity, and biome-specificity
Carbonic anhydrase (CA) enzymes catalyze the interconversion of carbon dioxide and bicarbonate with an efficiency exceeded only by superoxide dismutase. CA enzymes have convergently evolved multiple t...
www.biorxiv.org
January 14, 2025 at 12:47 PM
Our new preprint is out! A genomic and metagenomic dive into the diversity of microbial carbonic anhydrases. Huge thanks to the amazing team who made this possible!
@you-wren.bsky.social @laurameredith.bsky.social
www.biorxiv.org/content/10.1...
@you-wren.bsky.social @laurameredith.bsky.social
www.biorxiv.org/content/10.1...
Reposted by Mario Emilio Ernesto Franco
Our review is out in Nature Reviews Genetics! rdcu.be/d5AY2
We show how phylogeny-based methods can resolve the problem of non-independence in genomic datasets.
These methods must be considered an essential part of the comparative genomics toolkit.
@lauriebelch.bsky.social @stuwest.bsky.social
We show how phylogeny-based methods can resolve the problem of non-independence in genomic datasets.
These methods must be considered an essential part of the comparative genomics toolkit.
@lauriebelch.bsky.social @stuwest.bsky.social
A phylogenetic approach to comparative genomics
Nature Reviews Genetics - Controlling for phylogeny is essential in comparative genomics studies, because species, genomes and genes are not independent data points within statistical tests. The...
rdcu.be
January 8, 2025 at 1:19 PM
Our review is out in Nature Reviews Genetics! rdcu.be/d5AY2
We show how phylogeny-based methods can resolve the problem of non-independence in genomic datasets.
These methods must be considered an essential part of the comparative genomics toolkit.
@lauriebelch.bsky.social @stuwest.bsky.social
We show how phylogeny-based methods can resolve the problem of non-independence in genomic datasets.
These methods must be considered an essential part of the comparative genomics toolkit.
@lauriebelch.bsky.social @stuwest.bsky.social
Excited to share our latest preprint! 'Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi'. Deeply grateful to the U'Ren Lab @you-wren.bsky.social and JGI team.
tinyurl.com/u32xdpx9
tinyurl.com/u32xdpx9
Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi
Xylariales is one of the largest and most ecologically diverse fungal orders. Xylarialean fungi are well-known for their chemical diversity, reflecting a hyperdiversity of biosynthetic gene clusters (...
tinyurl.com
January 7, 2025 at 6:20 AM
Excited to share our latest preprint! 'Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi'. Deeply grateful to the U'Ren Lab @you-wren.bsky.social and JGI team.
tinyurl.com/u32xdpx9
tinyurl.com/u32xdpx9