Edukondalu Mullapudi
@edumullapudi.bsky.social
"Dedicated scientist with deep expertise in Single Particle Cryo-EM, X-ray Crystallography, Protein Biochemistry, Molecular Biology, and Virology. Passionate about uncovering the complexities of biological systems and driving innovative discoveries."
Reposted by Edukondalu Mullapudi
Architecture of an asymmetric mycobacterial short chain/long chain acyl-CoA carboxylase https://www.biorxiv.org/content/10.1101/2025.11.15.688623v1
November 16, 2025 at 3:17 AM
Architecture of an asymmetric mycobacterial short chain/long chain acyl-CoA carboxylase https://www.biorxiv.org/content/10.1101/2025.11.15.688623v1
Reposted by Edukondalu Mullapudi
Our new preprint is out:
www.biorxiv.org/content/10.1...
Cryo-EM structure of a multi-substrate mycobacterial ACCase reveals unique stoichiometry, a flexible AccE5-mediated β-barrel, and ~90° BC rotation upon substrate binding-insight into mycolic acid biosynthesis.
Huge thanks to my co-authors!
www.biorxiv.org/content/10.1...
Cryo-EM structure of a multi-substrate mycobacterial ACCase reveals unique stoichiometry, a flexible AccE5-mediated β-barrel, and ~90° BC rotation upon substrate binding-insight into mycolic acid biosynthesis.
Huge thanks to my co-authors!
| bioRxiv
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
November 17, 2025 at 3:40 AM
Our new preprint is out:
www.biorxiv.org/content/10.1...
Cryo-EM structure of a multi-substrate mycobacterial ACCase reveals unique stoichiometry, a flexible AccE5-mediated β-barrel, and ~90° BC rotation upon substrate binding-insight into mycolic acid biosynthesis.
Huge thanks to my co-authors!
www.biorxiv.org/content/10.1...
Cryo-EM structure of a multi-substrate mycobacterial ACCase reveals unique stoichiometry, a flexible AccE5-mediated β-barrel, and ~90° BC rotation upon substrate binding-insight into mycolic acid biosynthesis.
Huge thanks to my co-authors!
Our new preprint is out:
www.biorxiv.org/content/10.1...
Cryo-EM structure of a multi-substrate mycobacterial ACCase reveals unique stoichiometry, a flexible AccE5-mediated β-barrel, and ~90° BC rotation upon substrate binding-insight into mycolic acid biosynthesis.
Huge thanks to my co-authors!
www.biorxiv.org/content/10.1...
Cryo-EM structure of a multi-substrate mycobacterial ACCase reveals unique stoichiometry, a flexible AccE5-mediated β-barrel, and ~90° BC rotation upon substrate binding-insight into mycolic acid biosynthesis.
Huge thanks to my co-authors!
| bioRxiv
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
November 17, 2025 at 3:40 AM
Our new preprint is out:
www.biorxiv.org/content/10.1...
Cryo-EM structure of a multi-substrate mycobacterial ACCase reveals unique stoichiometry, a flexible AccE5-mediated β-barrel, and ~90° BC rotation upon substrate binding-insight into mycolic acid biosynthesis.
Huge thanks to my co-authors!
www.biorxiv.org/content/10.1...
Cryo-EM structure of a multi-substrate mycobacterial ACCase reveals unique stoichiometry, a flexible AccE5-mediated β-barrel, and ~90° BC rotation upon substrate binding-insight into mycolic acid biosynthesis.
Huge thanks to my co-authors!