Dzmitry Mukha
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dzmitrybio.bsky.social
Dzmitry Mukha
@dzmitrybio.bsky.social
Deeply passionate about unraveling the complexities of cancer metabolism. Working on short- and branched-chain fatty acids. Excelling in LC-MS metabolomics and lipidomics, I advocate for Reproducible Research and data sharing. Postdoc at Schug Lab.
February 10, 2025 at 4:18 AM
The article redefines SLC25A38 as a mitochondrial pyridoxal phosphate (PLP, “active” vitamin B6) transporter important at low PLP concentrations.

While working on glycine oxidation, the lack of association with GCS expression in CCLE was puzzling. Problem solved. Ty

www.nature.com/articles/s41...
SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation - Nature Communications
Pyridoxal 5’-phosphate (PLP, vitamin B6) is crucial for various metabolic processes. Here, the authors identified SLC25A38 as a key regulator of mitochondrial PLP levels using a genome-wide CRISPRi sc...
www.nature.com
January 28, 2025 at 12:27 PM