Isabelle Dupin
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dupinisabelle.bsky.social
Isabelle Dupin
@dupinisabelle.bsky.social
Professor of physiology. Lung Science lover // Chronic Respiratory Diseases // Organoids // Cell interactions

https://www.bronchialremodeling.com/bpco
Reposted by Isabelle Dupin
Vehicle emission standards must also account for atmospheric transformation to protect human health. Our new study shows that photochemical aging of EURO6d gasoline car emissions leads to an increase toxicity on human lung cells compared to fresh tailpipe emissions.
www.science.org/doi/10.1126/...
The efficiency of EURO 6d car particulate filters is compromised by atmospheric aging: In vitro toxicity of gasoline car exhaust
Atmospheric processing substantially toxifies tailpipe emissions from a EURO 6d gasoline car with a particulate filter.
www.science.org
June 4, 2025 at 3:40 AM
Reposted by Isabelle Dupin
Integrated Organoid Atlas benchmarks new protocols, even more impressive as a Highly Variable Cohort for comparison against perturbation and disease models: nature.com/articles/s41... Lead by @quanxu.bsky.social, in collaboration with Lennard Halle and @fabiantheis.bsky.social
An integrated transcriptomic cell atlas of human endoderm-derived organoids - Nature Genetics
The human endoderm-derived organoid cell atlas (HEOCA) presents an integrative analysis of single-cell transcriptomes across different conditions, sources and protocols. It compares cell types and sta...
nature.com
May 12, 2025 at 9:23 PM
Avis aux amatrices et amateurs de jolis modèles !
GDR organoïdes-École Thématique 2025 !
Nantes, 📅 7-11 Juillet

Découvrir les dernières avancées, participer à des travaux pratiques...  
C'est l'occasion de se former, réseauter & explorer les défis de demain.
🔗 organoides.sciencesconf.org

#Organoïdes2025 #Science #Recherche #Innovation #Formation
École thématique "Organoïdes": Modéliser des systèmes multicellulaires - Sciencesconf.org
organoides.sciencesconf.org
February 1, 2025 at 8:14 AM
More than happy to have been awarded an #ERCCoG grant for my KINTSUGI project ✨! We will be studying mechanisms of lung resilience to atmospheric pollution.
I cannot thank enough all the people who have helped to build the project, the @univbordeaux.bsky.social, the IUF and @inserm.bsky.social🙏.
. @dupinisabelle.bsky.social, prof. en physiologie explore les mécanismes qui permettent au poumon de s'adapter et de se réparer face à la pollution. Son projet "Kintsugi" ambitionne d’allier biologie, philosophie et modélisation pour déchiffrer ce processus fascinant www.u-bordeaux.fr/ac...
December 5, 2024 at 5:30 PM
Reposted by Isabelle Dupin
📣 Seeking for a postdoctoral scientist

To work with Bertrand Simon and me, on Tomographic Diffractive #Microscopy and cylindrical #organoids

🔬 🧫 🧑‍🔬

In @univbordeaux.bsky.social @cnrs.bsky.social IOGS LP2N

Please, write to Bertrand and myself for further information
January 20, 2024 at 1:59 PM
Very nice paper unravelling the key role of mesenchymal cells to shape epithelial layers in #organoids:
journals.plos.org/plosbiology/...
Direct contact is required, it is not only about diffusible factors.
Fibroblast-induced mammary epithelial branching depends on fibroblast contractility
Epithelial branching morphogenesis is an essential process in living organisms, creating organ-specific epithelial shapes. This study uses time-lapse imaging of fibroblast co-cultures with epithelial ...
journals.plos.org
January 17, 2024 at 6:45 AM