duenasm85.bsky.social
@duenasm85.bsky.social
Johne’s disease (JD), caused by Mycobacterium avium subspecies paratuberculosis (MAP), is a chronic infectious enteritis that threatens both domestic and wild ruminants, including the wood bison-a species of conservation concern in North America.
onixonpoint.substack.com/p/diagnostic...
Diagnostic Strategies and Strain Typing for Johne's Disease in Wood Bison (Bison bison athabascae)
Optimizing Detection and Understanding MAP Strain Diversity in a Threatened Wildlife Species
onixonpoint.substack.com
May 15, 2025 at 1:36 AM
From malnutrition-related diabetes to genetic forms like MODY5 and the debated link between Alzheimer’s and insulin resistance, the diabetes landscape is broader and more complex than ever.
onixonpoint.substack.com/p/type-5-dia...
Type 5 Diabetes: The Newly Recognized Disease, MODY5, and the Expanding Diabetes Spectrum-Including “Type 3 Diabetes” (Alzheimer’s)
From malnutrition-related diabetes to genetic forms like MODY5 and the debated link between Alzheimer’s and insulin resistance, the diabetes landscape is broader and more complex than ever.
onixonpoint.substack.com
May 14, 2025 at 5:49 PM
This study aimed to investigate the biopathological characteristics of two distinct E. maxima isolates collected from geographically separated backyard poultry populations in Iran.

onixonpoint.substack.com/p/intraspeci...
Intraspecific Variations in Biology and Pathogenesis of Two Eimeria maxima Isolates from Distinct Geographic Locations
Comparative Analysis Reveals Biological and Pathogenic Diversity Among E. maxima Strains in Iranian Poultry
onixonpoint.substack.com
May 8, 2025 at 2:27 AM
Inhibitory Effects of Manihot esculenta and Aloe barbadensis Leaf Extracts Against Poultry Eimeria Oocyst Sporulation: Alternatives to Antiprotozoal Resistance
onixonpoint.substack.com/p/inhibitory...
Inhibitory Effects of Manihot esculenta and Aloe barbadensis Leaf Extracts Against Poultry Eimeria Oocyst Sporulation: Alternatives to Antiprotozoal Resistance
Dose-Dependent, Plant-Based Inhibition of Eimeria Sporulation as a Sustainable Anticoccidial Strategy
onixonpoint.substack.com
May 6, 2025 at 1:49 AM
Grip strength is associated with a range of health outcomes, from type 2 diabetes to depression.

www.bbc.com/future/artic...
Grip strength: The test for your chances of living to 100
Grip strength is associated with a range of health outcomes, from type 2 diabetes to depression. Here’s how to check yours.
www.bbc.com
May 5, 2025 at 10:43 PM
OniX OnPoint Animal Health Newsletter: Advances in Poultry Coccidiosis Control: Genetics, Vaccines, and Natural Alternatives

Highlights from Recent Research on Immunization, Herbal Strategies, and Genetic Resistance in Poultry Health

onixonpoint.substack.com/p/advances-i...
OniX OnPoint Animal Health Newsletter: Advances in Poultry Coccidiosis Control: Genetics, Vaccines, and Natural Alternatives
Highlights from Recent Research on Immunization, Herbal Strategies, and Genetic Resistance in Poultry Health
onixonpoint.substack.com
May 5, 2025 at 11:43 AM
Human Monoclonal Antibodies: A Potential Countermeasure Against Clade 2.3.4.4b H5N1 Influenza

Characterization of Broadly Neutralizing mAbs and Protection in a Murine Challenge Model

onixonpoint.substack.com/p/human-mono...
Human Monoclonal Antibodies: A Potential Countermeasure Against Clade 2.3.4.4b H5N1 Influenza
Characterization of Broadly Neutralizing mAbs and Protection in a Murine Challenge Model
onixonpoint.substack.com
May 1, 2025 at 11:08 AM
Experimental H5N1 Infection in Dairy Cows: Clinical Outcomes and Viral Dynamics

Replication of HPAI H5N1 Clade 2.3.4.4b Genotype B3.13 in Holstein Dairy Cattle Mimics Field Observations

onixonpoint.substack.com/p/experiment...
Experimental H5N1 Infection in Dairy Cows: Clinical Outcomes and Viral Dynamics
Replication of HPAI H5N1 Clade 2.3.4.4b Genotype B3.13 in Holstein Dairy Cattle Mimics Field Observations
onixonpoint.substack.com
May 1, 2025 at 1:21 AM
Pre-existing Human T-Cell Immunity: A Key Defense Against H5N1 Influenza

Conservation of Influenza T-Cell Epitopes Between Seasonal Strains and H5N1 Suggests Cross-Reactivity

onixonpoint.substack.com/p/pre-existi...
Pre-existing Human T-Cell Immunity: A Key Defense Against H5N1 Influenza
Conservation of Influenza T-Cell Epitopes Between Seasonal Strains and H5N1 Suggests Cross-Reactivity
onixonpoint.substack.com
April 30, 2025 at 11:25 AM
Comparative Immunogenicity and Protection of H5N1 Vaccines in Geese

Evaluation of Five Commercial Vaccines Against Highly Pathogenic Avian Influenza Virus H5N1 Clade 2.3.4.4b in Fattening Geese

onixonpoint.substack.com/p/comparativ...
Comparative Immunogenicity and Protection of H5N1 Vaccines in Geese
Evaluation of Five Commercial Vaccines Against Highly Pathogenic Avian Influenza Virus H5N1 Clade 2.3.4.4b in Fattening Geese
onixonpoint.substack.com
April 30, 2025 at 1:04 AM
Human Monoclonal Antibodies: A Powerful Strategy Against H5N1 Influenza

Rapid Generation and Therapeutic Efficacy of mAbs from Convalescent Patients in a Murine Model

onixonpoint.substack.com/p/human-mono...
Human Monoclonal Antibodies: A Powerful Strategy Against H5N1 Influenza
Rapid Generation and Therapeutic Efficacy of mAbs from Convalescent Patients in a Murine Model
onixonpoint.substack.com
April 29, 2025 at 11:20 AM
Recombinant H5N6 Avian Influenza: Enhanced Pathogenicity and Transmissibility Through H9N2 Internal Genes

H5N6 viruses with H9N2-derived internal genes exhibit increased pathogenicity and aerosol transmissibility, posing a greater threat to human health.

onixonpoint.substack.com/p/recombinan...
Recombinant H5N6 Avian Influenza: Enhanced Pathogenicity and Transmissibility Through H9N2 Internal Genes
H5N6 viruses with H9N2-derived internal genes exhibit increased pathogenicity and aerosol transmissibility, posing a greater threat to human health.
onixonpoint.substack.com
April 29, 2025 at 1:08 AM
Bispecific PD-1/VEGF Inhibitors: The Next Leap in Cancer Immunotherapy

Clinical Momentum and Scientific Validation for Dual Checkpoint and Angiogenesis Blockade

onixonpoint.substack.com/p/bispecific...
Bispecific PD-1/VEGF Inhibitors: The Next Leap in Cancer Immunotherapy
Clinical Momentum and Scientific Validation for Dual Checkpoint and Angiogenesis Blockade
onixonpoint.substack.com
April 28, 2025 at 4:53 PM
OniX OnPoint Animal Health Newsletter: Navigating Avian Influenza: Vaccine Responses, Viral Evolution, and Transmission Risks in Poultry and Dairy Cattle

Latest Research on Avian Influenza Vaccines, Immunity, and Transmission in Poultry and Livestock

onixonpoint.substack.com/p/onix-onpoi...
OniX OnPoint Animal Health Newsletter: Navigating Avian Influenza: Vaccine Responses, Viral Evolution, and Transmission Risks in Poultry and Dairy Cattle
Latest Research on Avian Influenza Vaccines, Immunity, and Transmission in Poultry and Livestock
onixonpoint.substack.com
April 28, 2025 at 1:18 AM
Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice-An unbiased functional study

onixonpoint.substack.com/p/multiple-s...
Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice-An unbiased functional study
Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice-An unbiased functional study
onixonpoint.substack.com
April 27, 2025 at 8:30 PM
Targeted Restriction of Isoleucine and Valine, but Not Leucine, Promotes Metabolic Health and Offers New Strategies for Obesity and Diabetes Prevention

onixonpoint.substack.com/p/distinct-r...
Distinct Roles of Isoleucine and Valine in Mediating the Adverse Metabolic Effects of Branched-Chain Amino Acids
Targeted Restriction of Isoleucine and Valine, but Not Leucine, Promotes Metabolic Health and Offers New Strategies for Obesity and Diabetes Prevention
onixonpoint.substack.com
April 26, 2025 at 11:49 AM
Antibody-Drug Conjugates (ADCs): Precision Powerhouses Transforming Cancer Therapy

From concept to clinic—how ADCs are evolving to become smarter, safer, and more versatile weapons against cancer and beyond.

onixonpoint.substack.com/p/antibody-d...
Antibody-Drug Conjugates (ADCs): Precision Powerhouses Transforming Cancer Therapy
From concept to clinic—how ADCs are evolving to become smarter, safer, and more versatile weapons against cancer and beyond.
onixonpoint.substack.com
April 25, 2025 at 11:27 AM
Evolutionary Lineage-Specific Genomic Imprinting at the ZNF791 Locus

Discovery of Novel Imprinted Genes in Domesticated Animals

onixonpoint.substack.com/p/evolutiona...
Evolutionary Lineage-Specific Genomic Imprinting at the ZNF791 Locus
Discovery of Novel Imprinted Genes in Domesticated Animals
onixonpoint.substack.com
April 25, 2025 at 2:01 AM
YL201: A Promising Antibody-Drug Conjugate for Advanced Solid Tumors

Phase 1 Trial Demonstrates Encouraging Efficacy and Acceptable Safety Profile of a B7H3-Targeting ADC in Refractory Cancers

onixonpoint.substack.com/p/yl201-a-pr...
YL201: A Promising Antibody-Drug Conjugate for Advanced Solid Tumors
Phase 1 Trial Demonstrates Encouraging Efficacy and Acceptable Safety Profile of a B7H3-Targeting ADC in Refractory Cancers
onixonpoint.substack.com
April 24, 2025 at 11:28 AM
YL201: A Promising Antibody-Drug Conjugate for Advanced Solid Tumors

Phase 1 Trial Demonstrates Encouraging Efficacy and Acceptable Safety Profile of a B7H3-Targeting ADC in Refractory Cancers

onixonpoint.substack.com/p/yl201-a-pr...
YL201: A Promising Antibody-Drug Conjugate for Advanced Solid Tumors
Phase 1 Trial Demonstrates Encouraging Efficacy and Acceptable Safety Profile of a B7H3-Targeting ADC in Refractory Cancers
onixonpoint.substack.com
April 24, 2025 at 11:21 AM
Getah Virus Identified in Wild Boar in China: A Novel Epidemiological Threat

First Report and Genetic Characterization Reveals High Prevalence and GIII Subtype Identification in Wild Boar Population

onixonpoint.substack.com/p/getah-viru...
Getah Virus Identified in Wild Boar in China: A Novel Epidemiological Threat
First Report and Genetic Characterization Reveals High Prevalence and GIII Subtype Identification in Wild Boar Population
onixonpoint.substack.com
April 24, 2025 at 1:19 AM