Duane Choquesillo-Lazarte
duanechl.bsky.social
Duane Choquesillo-Lazarte
@duanechl.bsky.social
Chemical crystallographer & crystal grower. Tenured Scientist working at @LEC_CSIC, IACT-CSIC, Granada, Spain. I read comic books
Distinct packing, enantiotropic behaviour, and enhanced thermal stability > 102 °C. Sublimation proves effective for polymorphic screening in multicomponent pharmaceutical systems.
Great collaboration with @tonifrontera.bsky.social and Rafel Prohens 💎 @iactcsic.bsky.social
doi.org/10.1021/acs....
Exploring Sublimation as a Tool for Polymorphic Screening in Niflumic Acid–Caffeine Pharmaceutical Cocrystals
Sublimation has emerged as a powerful tool for polymorphic screening in pharmaceutical multicomponent materials. In this work, a combined strategy involving mechanochemistry and sublimation enables th...
doi.org
November 5, 2025 at 1:29 PM
Happy to see this work published! Exploring the impact of carbon-chain length in dicarboxylic acid coformers on the structure and properties of haloperidol salts and ionic cocrystals. Now at Crystal Growth & Design

doi.org/10.1021/acs....

Great collaboration with @tonifrontera.bsky.social!
Impact of the Coformer Carbon-Chain Length on the Properties of Haloperidol Pharmaceutical Salts
Haloperidol (HAL) is a conventional antipsychotic drug with poor aqueous solubility, which is associated with a major risk of side effects. In this context, crystal engineering has provided an efficie...
doi.org
May 8, 2025 at 6:39 AM
Now in Molecular Pharmaceutics @Mol_Pharm. Our approach to enhance drug loading capacity on apatite nanoparticles.
Check it out here: doi.org/10.1021/acs....

@LEC_CSIC @IACT_divulga
Enhanced Drug Loading Capacity Using the Dual Metformine–Dexketoprofren Salt on Nanoapatite Materials
Both apatite nanoparticles and multicomponent pharmaceutical materials have proved the ability to significantly improve the bioavailability of different drugs using different strategies. Herein, the u...
doi.org
April 25, 2025 at 10:42 AM
I had an incredible day surrounded by talented artists at the annual Christmas gathering in Jaén. Visiting the studio of my friend, the artist @raullaracomicart.bsky.social, was truly inspiring. I'm heading home not just with fantastic illustrations but also with a renewed sense of creativity.
December 19, 2024 at 11:10 PM