@nejm.org #UPDATE
🫀Immediate iFR-guided PCI ≈ Deferred MRI-guided PCI at 3 yrs
⚡No difference in death, MI, or HF hospitalization (HR 0.95, p=0.81)
🧠 Stroke/TIA lower with iFR
tinyurl.com/ystr7kvm
@nejm.org #UPDATE
🫀Immediate iFR-guided PCI ≈ Deferred MRI-guided PCI at 3 yrs
⚡No difference in death, MI, or HF hospitalization (HR 0.95, p=0.81)
🧠 Stroke/TIA lower with iFR
tinyurl.com/ystr7kvm
@nejm.org PARTNER 3 Trial #updates
👉No sig. diff in 🪦 death, 🧠 stroke, or 🏥 re-hospitalization
Valve durability 💪 similar too.
#TAVR #CardioTwitter #MedTwitter #AorticStenosis
tinyurl.com/yd748jxt
@nejm.org PARTNER 3 Trial #updates
👉No sig. diff in 🪦 death, 🧠 stroke, or 🏥 re-hospitalization
Valve durability 💪 similar too.
#TAVR #CardioTwitter #MedTwitter #AorticStenosis
tinyurl.com/yd748jxt
✅ ↑ Sensitivity 92% vs 71%
✅ ↓ False activations 7.9% vs 41.8%
✅ Better detection of LCx (40.6%) misses
#Cardiology #STEMI #AI @jaccjournals.bsky.social
tinyurl.com/54m23uj4
✅ ↑ Sensitivity 92% vs 71%
✅ ↓ False activations 7.9% vs 41.8%
✅ Better detection of LCx (40.6%) misses
#Cardiology #STEMI #AI @jaccjournals.bsky.social
tinyurl.com/54m23uj4
🫧Lung US→Detect recruitment, monitor aeration
💪Diaphragm US→Track diaphragm geometry, contractility, predict NIV/weaning outcomes.
📈 Integrating both helps balance recruitment vs overdistension.
tinyurl.com/35ttec4f
🫧Lung US→Detect recruitment, monitor aeration
💪Diaphragm US→Track diaphragm geometry, contractility, predict NIV/weaning outcomes.
📈 Integrating both helps balance recruitment vs overdistension.
tinyurl.com/35ttec4f
Conditional recommendations-
🫢 Acute dyspnea / resp failure
💧 Targeted volume management
❤️ Cardiogenic shock
🦠 Septic shock
+/-⚖️ Cardiac arrest
#POCUS #ICU #PCCM @sccmcriticalcare.bsky.social
tinyurl.com/5a7w3k8k
Conditional recommendations-
🫢 Acute dyspnea / resp failure
💧 Targeted volume management
❤️ Cardiogenic shock
🦠 Septic shock
+/-⚖️ Cardiac arrest
#POCUS #ICU #PCCM @sccmcriticalcare.bsky.social
tinyurl.com/5a7w3k8k
🧑🎓AQUATIC Trial (NEJM Oct 2025):
✅Adding aspirin ↑ CV events, ↑ mortality, & ↑ major bleeding vs placebo
👉 No ischemic benefit
❤️🔥More harm
@nejm.org #Cardio #updates
tinyurl.com/2zc5zh38
🧑🎓AQUATIC Trial (NEJM Oct 2025):
✅Adding aspirin ↑ CV events, ↑ mortality, & ↑ major bleeding vs placebo
👉 No ischemic benefit
❤️🔥More harm
@nejm.org #Cardio #updates
tinyurl.com/2zc5zh38
🔹Steroids- acute inflammation
🔹Mycophenolate/Cyclophosphamide- immunosuppression backbone
🔹Rituximab/Tacrolimus- for refractory disease
🔹Nintedanib/Tocilizumab- antifibrotic & targeted
#ILD #PulmCC @atscommunity.bsky.social
tinyurl.com/kyyvnftu
🔹Steroids- acute inflammation
🔹Mycophenolate/Cyclophosphamide- immunosuppression backbone
🔹Rituximab/Tacrolimus- for refractory disease
🔹Nintedanib/Tocilizumab- antifibrotic & targeted
#ILD #PulmCC @atscommunity.bsky.social
tinyurl.com/kyyvnftu
🔹RA-UIP pattern
🔹SSc-NSIP
🔹IIM (Idio Inflam Myopathy)– NSIP + OP overlap
#Updates
#PulmCC #Rheum #ILD @atscommunity.bsky.social
tinyurl.com/kyyvnftu
🔹RA-UIP pattern
🔹SSc-NSIP
🔹IIM (Idio Inflam Myopathy)– NSIP + OP overlap
#Updates
#PulmCC #Rheum #ILD @atscommunity.bsky.social
tinyurl.com/kyyvnftu
🫁 Brensocatib reduces exacerbations in non-CF bronchiectasis
💊 Targets neutrophilic inflammation via DPP1 inhibition, a novel approach beyond antibiotics
#PulmCC #Bronchiectasis @nejm.org
tinyurl.com/ycxz9xhk
🫁 Brensocatib reduces exacerbations in non-CF bronchiectasis
💊 Targets neutrophilic inflammation via DPP1 inhibition, a novel approach beyond antibiotics
#PulmCC #Bronchiectasis @nejm.org
tinyurl.com/ycxz9xhk
Presenting multiple 🪧 posters, a 🎤 rapid-fire oral presentation, and honored to be a 🏅 semifinalist for the Top Scientific Abstract Poster Award!
Grateful & excited to share our work 🙌
#PCCM #CHESTSoMe @accpchest.bsky.social
Presenting multiple 🪧 posters, a 🎤 rapid-fire oral presentation, and honored to be a 🏅 semifinalist for the Top Scientific Abstract Poster Award!
Grateful & excited to share our work 🙌
#PCCM #CHESTSoMe @accpchest.bsky.social
Honored to be part of the Social Media team - can’t wait to dive into sessions, meet colleagues & share it all with you. #CHESTConference #PulmCC #MedTwitter #CHESTSoMe @accpchest.bsky.social
Honored to be part of the Social Media team - can’t wait to dive into sessions, meet colleagues & share it all with you. #CHESTConference #PulmCC #MedTwitter #CHESTSoMe @accpchest.bsky.social
✅Lung-protective vent(Vt 4–8 mL/kg PBW, Pplat <30)
✅Prone >12 h/day for severe ARDS
🟡Consider: Steroids, VV-ECMO, NMB, higher PEEP (no LRMs)
🚫No HFOV & prolonged LRMs
@atscommunity.bsky.social
#ARDS #CriticalCare #Pulm #ICU
tinyurl.com/sxuwd3f5
✅Lung-protective vent(Vt 4–8 mL/kg PBW, Pplat <30)
✅Prone >12 h/day for severe ARDS
🟡Consider: Steroids, VV-ECMO, NMB, higher PEEP (no LRMs)
🚫No HFOV & prolonged LRMs
@atscommunity.bsky.social
#ARDS #CriticalCare #Pulm #ICU
tinyurl.com/sxuwd3f5
⚕️FDA Approves First Medication for Obstructive Sleep Apnea
💊Drug: Weekly tirzepatide > placebo
🧑🤝🧑Pop: OSA + obesity (no non-obese)
👉Effect: ↓AHI, ↓wt, ↓SBP, ↓hsCRP @ 52wks
@nejm.org @fda.gov
tinyurl.com/mrytwruc
⚕️FDA Approves First Medication for Obstructive Sleep Apnea
💊Drug: Weekly tirzepatide > placebo
🧑🤝🧑Pop: OSA + obesity (no non-obese)
👉Effect: ↓AHI, ↓wt, ↓SBP, ↓hsCRP @ 52wks
@nejm.org @fda.gov
tinyurl.com/mrytwruc
🧑🔧Mechanism: H₂S scavenger → ↑vascular tone
💊Intervention: 5 g IV hydroxocobalamin ×1 vs placebo
👉Result: ↓vasopressor need (−36% vs 4%); safe & feasible
tinyurl.com/3de9k7c8 @accpchest.bsky.social #Sepsis
🧑🔧Mechanism: H₂S scavenger → ↑vascular tone
💊Intervention: 5 g IV hydroxocobalamin ×1 vs placebo
👉Result: ↓vasopressor need (−36% vs 4%); safe & feasible
tinyurl.com/3de9k7c8 @accpchest.bsky.social #Sepsis
🩸ANCA Vasculitis:GPA→PR3+, MPA→MPO+, EGPA→MPO±
🩸Anti-GBM: Ab 95–100% sens/spec
🩸CTD: SLE→dsDNA/Sm/C1q; APS→aCL/Lupus AntiCoag; RA→RF/anti-CCP; MCTD→Anti-RNP
@europeanrespsoc.bsky.social
tinyurl.com/4zz3fh74
🩸ANCA Vasculitis:GPA→PR3+, MPA→MPO+, EGPA→MPO±
🩸Anti-GBM: Ab 95–100% sens/spec
🩸CTD: SLE→dsDNA/Sm/C1q; APS→aCL/Lupus AntiCoag; RA→RF/anti-CCP; MCTD→Anti-RNP
@europeanrespsoc.bsky.social
tinyurl.com/4zz3fh74
🙀Induction: Steroids+CYC/RTX±PLEX ±IVIG/AC (APS)
😼Maintenance: Per etiology-Steroids/AZA/MTX/CYC/RTX
@europeanrespsoc.bsky.social doi.org/10.1183/2073...
🙀Induction: Steroids+CYC/RTX±PLEX ±IVIG/AC (APS)
😼Maintenance: Per etiology-Steroids/AZA/MTX/CYC/RTX
@europeanrespsoc.bsky.social doi.org/10.1183/2073...
👉<6 mm:Low risk-no FU;High risk-optional CT@ 12 mo
👉6–8 mm:CT@ 6-12 mo→ consider @ 18–24 mo
👉>8 mm:CT@ 3 mo±PET/CT or biopsy
⚡️Use most suspicious nodule if multiple
🤯risk = smoker/upper lobe/morphology @rsnasky.bsky.social
doi.org/10.1148/radi...
👉<6 mm:Low risk-no FU;High risk-optional CT@ 12 mo
👉6–8 mm:CT@ 6-12 mo→ consider @ 18–24 mo
👉>8 mm:CT@ 3 mo±PET/CT or biopsy
⚡️Use most suspicious nodule if multiple
🤯risk = smoker/upper lobe/morphology @rsnasky.bsky.social
doi.org/10.1148/radi...
Promise is huge but validation, ethics & data quality remain key.
#Nephrology #AI @jasminenephro.bsky.social Nephro DOI: 10.1097/MCC.0000000000001202
Promise is huge but validation, ethics & data quality remain key.
#Nephrology #AI @jasminenephro.bsky.social Nephro DOI: 10.1097/MCC.0000000000001202
Physician burnout overlaps heavily w/ depression
Key driver: workload(long hours spike symptoms 5-6x in residents)
Fixes: Reduce hours,add support(scribes/AI), mindfulness/CBT #burnout #wellness @nejm.org
nejm.org/doi/full/10....
Physician burnout overlaps heavily w/ depression
Key driver: workload(long hours spike symptoms 5-6x in residents)
Fixes: Reduce hours,add support(scribes/AI), mindfulness/CBT #burnout #wellness @nejm.org
nejm.org/doi/full/10....
Large-bore mechanical thrombectomy (LBMT) vs catheter-directed thrombolysis (CDT) for intermediate-risk PE.
LBMT✅=fewer clinical deteriorations, less ICU use, and shorter hospital stay with no ↑ in mortality or bleeding. @ahascience.bsky.social
www.ahajournals.org/doi/10.1161/...
Large-bore mechanical thrombectomy (LBMT) vs catheter-directed thrombolysis (CDT) for intermediate-risk PE.
LBMT✅=fewer clinical deteriorations, less ICU use, and shorter hospital stay with no ↑ in mortality or bleeding. @ahascience.bsky.social
www.ahajournals.org/doi/10.1161/...
@accpchest.bsky.social
@accpchest.bsky.social