Paula Lindner
@drpaulalindner.bsky.social
Scientific Product Manager at Gentian
#DiagnosticEfficiency #Biomarkers
#Calprotectin #Rheumatology #RheumSky
#NT-proBNP #CardioSky
Views expressed are my own.
#DiagnosticEfficiency #Biomarkers
#Calprotectin #Rheumatology #RheumSky
#NT-proBNP #CardioSky
Views expressed are my own.
Pinned
Serum Calprotectin (S100A8/A9) in Diagnosis, Monitoring, and Prognosis of Rheumatic Diseases
<p><strong>Available On-Demand</strong></p>
<p>Serum calprotectin plays a critical role in the pathogenesis of rheumatoid arthritis (RA), as it triggers chemotaxis, phagocyte migration, and modulation...
selectscience.streamgo.live
🗣️Webinar by Prof. Dr. Marija Jeluŝić now available on demand 🌐
Serum Calprotectin (S100A8/A9) in Diagnosis, Monitoring, and Prognosis of Rheumatic Diseases
selectscience.streamgo.live/serum-calpro...
#RheumaSky #Calprotectin #Inflammation
Serum Calprotectin (S100A8/A9) in Diagnosis, Monitoring, and Prognosis of Rheumatic Diseases
selectscience.streamgo.live/serum-calpro...
#RheumaSky #Calprotectin #Inflammation
Exploring the Relevance of S100A8 and S100A9 Proteins in Preeclampsia: A Narrative Review
#Calprotectin
www.mdpi.com/1422-0067/26...
#Calprotectin
www.mdpi.com/1422-0067/26...
November 4, 2025 at 2:20 PM
Exploring the Relevance of S100A8 and S100A9 Proteins in Preeclampsia: A Narrative Review
#Calprotectin
www.mdpi.com/1422-0067/26...
#Calprotectin
www.mdpi.com/1422-0067/26...
The role of inflammation in acute coronary syndrome: A systematic review on biochemical inflammatory assessment and anti-inflammatory therapies
#CardioSky #calprotectin
www.nmcd-journal.com/article/S093...
#CardioSky #calprotectin
www.nmcd-journal.com/article/S093...
The role of inflammation in acute coronary syndrome: A systematic review on biochemical inflammatory assessment and anti-inflammatory therapies
Low-grade inflammation is a key driver of the pathogenesis and complications of acute
coronary syndromes (ACS), playing a central role in plaque development and destabilization.
This systematic review...
www.nmcd-journal.com
October 28, 2025 at 11:55 AM
The role of inflammation in acute coronary syndrome: A systematic review on biochemical inflammatory assessment and anti-inflammatory therapies
#CardioSky #calprotectin
www.nmcd-journal.com/article/S093...
#CardioSky #calprotectin
www.nmcd-journal.com/article/S093...
𝗡𝗲𝘄 𝗶𝗻𝘀𝗶𝗴𝗵𝘁𝘀 𝗶𝗻𝘁𝗼 𝗲𝗮𝗿𝗹𝘆 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝗶𝘀 𝗼𝗳 𝗻𝗲𝗼𝗻𝗮𝘁𝗮𝗹 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻𝘀 At this year’s joint European Neonatal Societies #jENS2025 Congress, new evidence will be presented on the role of serum #calprotectin in improving early diagnosis of neonatal infections.
www.gentian.com/news/calprot...
www.gentian.com/news/calprot...
Calprotectin in neonatal infections - jENS Congress 2025
New evidence will be shared on the role of blood calprotectin in the early diagnosis of neonatal infections.
www.gentian.com
October 23, 2025 at 8:25 AM
𝗡𝗲𝘄 𝗶𝗻𝘀𝗶𝗴𝗵𝘁𝘀 𝗶𝗻𝘁𝗼 𝗲𝗮𝗿𝗹𝘆 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝗶𝘀 𝗼𝗳 𝗻𝗲𝗼𝗻𝗮𝘁𝗮𝗹 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻𝘀 At this year’s joint European Neonatal Societies #jENS2025 Congress, new evidence will be presented on the role of serum #calprotectin in improving early diagnosis of neonatal infections.
www.gentian.com/news/calprot...
www.gentian.com/news/calprot...
Neutrophil activation in juvenile dermatomyositis: associations with muscle function and disease progression
#CirculatingCalprotectin and MPO-DNA as potential biomarkers for JDM muscle inflammation and functional outcomes.
#RheumSky
ped-rheum.biomedcentral.com/articles/10....
#CirculatingCalprotectin and MPO-DNA as potential biomarkers for JDM muscle inflammation and functional outcomes.
#RheumSky
ped-rheum.biomedcentral.com/articles/10....
Neutrophil activation in juvenile dermatomyositis: associations with muscle function and disease progression - Pediatric Rheumatology
Background Juvenile dermatomyositis (JDM) is an inflammatory vasculopathy characterized by muscle weakness and systemic inflammation. This study aimed to investigate the clinical utility of neutrophil...
ped-rheum.biomedcentral.com
October 15, 2025 at 7:08 AM
Neutrophil activation in juvenile dermatomyositis: associations with muscle function and disease progression
#CirculatingCalprotectin and MPO-DNA as potential biomarkers for JDM muscle inflammation and functional outcomes.
#RheumSky
ped-rheum.biomedcentral.com/articles/10....
#CirculatingCalprotectin and MPO-DNA as potential biomarkers for JDM muscle inflammation and functional outcomes.
#RheumSky
ped-rheum.biomedcentral.com/articles/10....
👉Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein
#RheumSky #CirculatingCalprotectin
rmdopen.bmj.com/content/11/3...
#RheumSky #CirculatingCalprotectin
rmdopen.bmj.com/content/11/3...
Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein
Objectives C reactive protein (CRP) is frequently normal in psoriatic arthritis (PsA) despite active disease, complicating inflammation assessment. This study aimed to evaluate alternative biomarkers ...
rmdopen.bmj.com
October 6, 2025 at 7:32 AM
👉Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein
#RheumSky #CirculatingCalprotectin
rmdopen.bmj.com/content/11/3...
#RheumSky #CirculatingCalprotectin
rmdopen.bmj.com/content/11/3...
Great depate at #PReS2025 between Dirk Föll and Joost Swart. Engaging and entertaining to follow those 2 outstanding speakers exchanging arguments.
The futures will hopefully be personalised medicine also for IRDs and biomarkers will play a crucial role.
#RheumSky #calprotectin
The futures will hopefully be personalised medicine also for IRDs and biomarkers will play a crucial role.
#RheumSky #calprotectin
September 18, 2025 at 8:51 AM
Great depate at #PReS2025 between Dirk Föll and Joost Swart. Engaging and entertaining to follow those 2 outstanding speakers exchanging arguments.
The futures will hopefully be personalised medicine also for IRDs and biomarkers will play a crucial role.
#RheumSky #calprotectin
The futures will hopefully be personalised medicine also for IRDs and biomarkers will play a crucial role.
#RheumSky #calprotectin
Year in review at #PReS2025 highlighting again the new Still's recommendations, endorsing biomarkers in diagnosis including #calprotectin
Visit us at booth 4 to learn about Gentian GCAL an automated calprotectin assay.
#RheumSky
Visit us at booth 4 to learn about Gentian GCAL an automated calprotectin assay.
#RheumSky
September 17, 2025 at 5:14 PM
Year in review at #PReS2025 highlighting again the new Still's recommendations, endorsing biomarkers in diagnosis including #calprotectin
Visit us at booth 4 to learn about Gentian GCAL an automated calprotectin assay.
#RheumSky
Visit us at booth 4 to learn about Gentian GCAL an automated calprotectin assay.
#RheumSky
🧬 Review: S100A8/A9 (#calprotectin) drives inflammation in CVD - fueling atherosclerosis, HF & arrhythmias.
🔍 Promising biomarker & therapeutic target
👉The alarmin tandem: unraveling the complex effect of S100A8/A9 – from atherosclerosis to cardiac arrhythmias
www.frontiersin.org/journals/imm...
🔍 Promising biomarker & therapeutic target
👉The alarmin tandem: unraveling the complex effect of S100A8/A9 – from atherosclerosis to cardiac arrhythmias
www.frontiersin.org/journals/imm...
September 16, 2025 at 12:14 PM
🧬 Review: S100A8/A9 (#calprotectin) drives inflammation in CVD - fueling atherosclerosis, HF & arrhythmias.
🔍 Promising biomarker & therapeutic target
👉The alarmin tandem: unraveling the complex effect of S100A8/A9 – from atherosclerosis to cardiac arrhythmias
www.frontiersin.org/journals/imm...
🔍 Promising biomarker & therapeutic target
👉The alarmin tandem: unraveling the complex effect of S100A8/A9 – from atherosclerosis to cardiac arrhythmias
www.frontiersin.org/journals/imm...
👉 Visit Gentian at Booth 4 at #PReS2025 to discover how GCAL® #calprotectin improves early inflammation detection, flare prediction, and treatment monitoring in pediatric rheumatology.
September 15, 2025 at 12:50 PM
👉 Visit Gentian at Booth 4 at #PReS2025 to discover how GCAL® #calprotectin improves early inflammation detection, flare prediction, and treatment monitoring in pediatric rheumatology.
September 11, 2025 at 7:28 AM
Happy to share the newest Gentian GCAL newsletter. Tune in for updates and insights. #CirculatingCalprotectin #RheumSky
www.linkedin.com/pulse/circul...
www.linkedin.com/pulse/circul...
Circulating calprotectin - the power to assess inflammation 2/2025
As we move into the second half of 2025, we are pleased to provide an update on GCAL® - our assay for circulating calprotectin - and to highlight recent research and studies that continue to expand kn...
www.linkedin.com
September 9, 2025 at 9:53 AM
Happy to share the newest Gentian GCAL newsletter. Tune in for updates and insights. #CirculatingCalprotectin #RheumSky
www.linkedin.com/pulse/circul...
www.linkedin.com/pulse/circul...
Fresh off the press, this review takes a deep look into #CirculatingCalprotectin in GCA.
www.frontiersin.org/journals/imm...
#RheumSky
www.frontiersin.org/journals/imm...
#RheumSky
Frontiers | The role of calprotectin in giant cell arteritis - from pathophysiology to possible clinical applications
Giant cell arteritis (GCA) is an immune-mediated vasculitis predominantly affecting individuals aged 50 years and older, with clinical manifestations often o...
www.frontiersin.org
September 2, 2025 at 12:27 PM
Fresh off the press, this review takes a deep look into #CirculatingCalprotectin in GCA.
www.frontiersin.org/journals/imm...
#RheumSky
www.frontiersin.org/journals/imm...
#RheumSky
Day 2 at #ESC2025. Packed with engaging sessions.
Extra shout-out to the paper badge holders, nice alternative to the usual plastic versions. 💚
Extra shout-out to the paper badge holders, nice alternative to the usual plastic versions. 💚
August 30, 2025 at 12:56 PM
Day 2 at #ESC2025. Packed with engaging sessions.
Extra shout-out to the paper badge holders, nice alternative to the usual plastic versions. 💚
Extra shout-out to the paper badge holders, nice alternative to the usual plastic versions. 💚
Countdown to Friday!
Join me together with the cardiology community at #ESCCongress 2025 with #WCCCardio. See you there! bit.ly/2SuZgbc
#CardioSky
Join me together with the cardiology community at #ESCCongress 2025 with #WCCCardio. See you there! bit.ly/2SuZgbc
#CardioSky
August 25, 2025 at 12:38 PM
Countdown to Friday!
Join me together with the cardiology community at #ESCCongress 2025 with #WCCCardio. See you there! bit.ly/2SuZgbc
#CardioSky
Join me together with the cardiology community at #ESCCongress 2025 with #WCCCardio. See you there! bit.ly/2SuZgbc
#CardioSky
💥 New biomarker insight for #pulmonaryembolism
#Calprotectin is up in PE and tracks with worse RV function (↓TAPSE, ↓RV-Sm). No link to D-dimer or troponin.
Potential new RV stress marker?
pmc.ncbi.nlm.nih.gov/articles/PMC...
#Calprotectin is up in PE and tracks with worse RV function (↓TAPSE, ↓RV-Sm). No link to D-dimer or troponin.
Potential new RV stress marker?
pmc.ncbi.nlm.nih.gov/articles/PMC...
August 5, 2025 at 12:17 PM
💥 New biomarker insight for #pulmonaryembolism
#Calprotectin is up in PE and tracks with worse RV function (↓TAPSE, ↓RV-Sm). No link to D-dimer or troponin.
Potential new RV stress marker?
pmc.ncbi.nlm.nih.gov/articles/PMC...
#Calprotectin is up in PE and tracks with worse RV function (↓TAPSE, ↓RV-Sm). No link to D-dimer or troponin.
Potential new RV stress marker?
pmc.ncbi.nlm.nih.gov/articles/PMC...
New biomarkers (of the 2024 recommendations) remain underutilized. S100 proteins ( #calprotectin ) are used by only 27% and 40% of respondents indicated lack of access.
But calprotectin is available as automated assay for labs (Siemens, Beckman and open channel).
pubmed.ncbi.nlm.nih.gov/40629829/
But calprotectin is available as automated assay for labs (Siemens, Beckman and open channel).
pubmed.ncbi.nlm.nih.gov/40629829/
August 4, 2025 at 10:25 AM
New biomarkers (of the 2024 recommendations) remain underutilized. S100 proteins ( #calprotectin ) are used by only 27% and 40% of respondents indicated lack of access.
But calprotectin is available as automated assay for labs (Siemens, Beckman and open channel).
pubmed.ncbi.nlm.nih.gov/40629829/
But calprotectin is available as automated assay for labs (Siemens, Beckman and open channel).
pubmed.ncbi.nlm.nih.gov/40629829/
👏 SelectScience editorial on #CirculatingCalprotectin received an award for the best ''Clinical Diagnostics Editorial Article of the Year'' at #ADLM this year.
#RheumSky
www.selectscience.net/article/how-...
#RheumSky
www.selectscience.net/article/how-...
How serum calprotectin is transforming rheumatic disease diagnosis
Discover how serum calprotectin is advancing the diagnosis, monitoring, and treatment of rheumatic diseases. Learn about its role in predicting flare-ups and guiding personalized care.
www.selectscience.net
August 4, 2025 at 8:19 AM
👏 SelectScience editorial on #CirculatingCalprotectin received an award for the best ''Clinical Diagnostics Editorial Article of the Year'' at #ADLM this year.
#RheumSky
www.selectscience.net/article/how-...
#RheumSky
www.selectscience.net/article/how-...
👉Where Do We Stand in the Management of Rheumatoid Arthritis Ahead of EULAR/ACR 2025?
#RheumSky #Rheumatology
www.mdpi.com/2039-7283/15...
#RheumSky #Rheumatology
www.mdpi.com/2039-7283/15...
July 4, 2025 at 12:04 PM
👉Where Do We Stand in the Management of Rheumatoid Arthritis Ahead of EULAR/ACR 2025?
#RheumSky #Rheumatology
www.mdpi.com/2039-7283/15...
#RheumSky #Rheumatology
www.mdpi.com/2039-7283/15...
''Serum S100A8/A9 concentration at ICU admission is a significant predictor of 28-day mortality risk in sepsis patients''
#CirculatingCalprotectin #Sepsis
www.frontiersin.org/journals/cel...
#CirculatingCalprotectin #Sepsis
www.frontiersin.org/journals/cel...
Frontiers | Assessment of S100A8/A9 and resistin as predictive biomarkers for mortality in critically ill patients with sepsis
IntroductionSepsis is associated with high mortality. Early intervention is crucial to reducing sepsis-related mortality. This study aims to assess the clini...
www.frontiersin.org
July 1, 2025 at 12:40 PM
''Serum S100A8/A9 concentration at ICU admission is a significant predictor of 28-day mortality risk in sepsis patients''
#CirculatingCalprotectin #Sepsis
www.frontiersin.org/journals/cel...
#CirculatingCalprotectin #Sepsis
www.frontiersin.org/journals/cel...
Review: Biomarkers in juvenile idiopathic arthritis: towards precision diagnosis and personalized therapy?
#CirculatingCalprotectin as promising tool for monitoring and prognosis in JIA by its ability to predict flares and subclinical inflammation.
#RheumSky
journals.lww.com/co-rheumatol...
#CirculatingCalprotectin as promising tool for monitoring and prognosis in JIA by its ability to predict flares and subclinical inflammation.
#RheumSky
journals.lww.com/co-rheumatol...
Biomarkers in juvenile idiopathic arthritis: towards... : Current Opinion in Rheumatology
years, research has increasingly focused on the identification and validation of biomarkers to enhance diagnostic precision, predict disease course, and guide therapeutic decisions.
Recent findings
...
journals.lww.com
June 24, 2025 at 12:15 PM
Review: Biomarkers in juvenile idiopathic arthritis: towards precision diagnosis and personalized therapy?
#CirculatingCalprotectin as promising tool for monitoring and prognosis in JIA by its ability to predict flares and subclinical inflammation.
#RheumSky
journals.lww.com/co-rheumatol...
#CirculatingCalprotectin as promising tool for monitoring and prognosis in JIA by its ability to predict flares and subclinical inflammation.
#RheumSky
journals.lww.com/co-rheumatol...
Reposted by Paula Lindner
#MedNews - Calprotectin could serve as a biomarker for #ASCVD beyond the current traditional cardiovascular risk factors.
Read the full story 👉 buff.ly/GxJoGHM
#CardioSky #calprotectin
Read the full story 👉 buff.ly/GxJoGHM
#CardioSky #calprotectin
Calprotectin shows potential as a biomarker for atherosclerotic CV disease risk
Calprotectin could serve as a biomarker for atherosclerotic cardiovascular disease beyond the current traditional cardiovascular risk factors.
buff.ly
June 7, 2025 at 10:54 AM
#MedNews - Calprotectin could serve as a biomarker for #ASCVD beyond the current traditional cardiovascular risk factors.
Read the full story 👉 buff.ly/GxJoGHM
#CardioSky #calprotectin
Read the full story 👉 buff.ly/GxJoGHM
#CardioSky #calprotectin
🗣️ #CirculatingCalprotectin identified as a crucial biomarker and potential therapeutic target of fulminant myocarditis.
High levels associated with longer hospital stays and higher risks of adverse outcomes.
#CardioSky
www.sciencedirect.com/science/arti...
High levels associated with longer hospital stays and higher risks of adverse outcomes.
#CardioSky
www.sciencedirect.com/science/arti...
Plasma proteomics identifies S100A8/A9 as a novel biomarker and therapeutic target for fulminant myocarditis
Fulminant myocarditis (FM) is a lethal inflammatory myocardial disease characterized by rapid progression and poor prognosis. Investigating plasma pro…
www.sciencedirect.com
June 10, 2025 at 11:52 AM
🗣️ #CirculatingCalprotectin identified as a crucial biomarker and potential therapeutic target of fulminant myocarditis.
High levels associated with longer hospital stays and higher risks of adverse outcomes.
#CardioSky
www.sciencedirect.com/science/arti...
High levels associated with longer hospital stays and higher risks of adverse outcomes.
#CardioSky
www.sciencedirect.com/science/arti...
👉S100A9 (subunit of #calprotectin) showed high sensitivity in detecting septic shock and forecasting clinical outcomes.
journals.plos.org/plosone/arti...
journals.plos.org/plosone/arti...
The role of S100A9 as a diagnostic and prognostic biomarker in septic shock
Background Sepsis is a severe and potentially fatal systemic condition marked by excessive immune defense against infection. Within this research, we explored the serum concentration of S100A9 during ...
journals.plos.org
June 10, 2025 at 11:50 AM
👉S100A9 (subunit of #calprotectin) showed high sensitivity in detecting septic shock and forecasting clinical outcomes.
journals.plos.org/plosone/arti...
journals.plos.org/plosone/arti...