James Conway
@drjamesconway.bsky.social
Research Fellow studying alpha-synucleinopathies (Bartels Lab) @UKDRI @UCL. Formerly of Kramer lab. Views are my own
Reposted by James Conway
New research has revealed how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice co-led by Dr @soyonhonglab.bsky.social & Dr Tim Bartels @ukdri.ac.uk @uclqsion.bsky.social @uclbrainscience.bsky.social
Targeting the gut's immune system could tackle early stages of Parkinson's
New research reveals how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice led by scientists at the UK D...
www.ucl.ac.uk
January 29, 2026 at 11:26 AM
New research has revealed how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice co-led by Dr @soyonhonglab.bsky.social & Dr Tim Bartels @ukdri.ac.uk @uclqsion.bsky.social @uclbrainscience.bsky.social
Reposted by James Conway
Could targeting the gut's immune system tackle the early stages of Parkinson's? 🧠
A new study from @soyonhonglab.bsky.social & Tim Bartels (UK DRI at UCL) has revealed how Parkinson’s spreads from the gut to the brain - with the help of immune cells.
Read more 👉 www.ukdri.ac.uk/news-and-eve...
A new study from @soyonhonglab.bsky.social & Tim Bartels (UK DRI at UCL) has revealed how Parkinson’s spreads from the gut to the brain - with the help of immune cells.
Read more 👉 www.ukdri.ac.uk/news-and-eve...
Targeting the gut's immune system could tackle early stages of Parkinson's
New research, led by Dr Soyon Hong and Dr Tim Bartels at the UK DRI at UCL, has revealed how Parkinson’s spreads from the gut to the brain, with the hel
www.ukdri.ac.uk
January 28, 2026 at 4:25 PM
Could targeting the gut's immune system tackle the early stages of Parkinson's? 🧠
A new study from @soyonhonglab.bsky.social & Tim Bartels (UK DRI at UCL) has revealed how Parkinson’s spreads from the gut to the brain - with the help of immune cells.
Read more 👉 www.ukdri.ac.uk/news-and-eve...
A new study from @soyonhonglab.bsky.social & Tim Bartels (UK DRI at UCL) has revealed how Parkinson’s spreads from the gut to the brain - with the help of immune cells.
Read more 👉 www.ukdri.ac.uk/news-and-eve...
Our paper is finally out!
We position intestinal muscularis macrophages as early initiators of α-synuclein pathology and dopaminergic neurodegeneration in Parkinson’s models. They also drive local CD4⁺ T cell expansion, which subsequently migrates from gut to brain
www.nature.com/articles/s41...
We position intestinal muscularis macrophages as early initiators of α-synuclein pathology and dopaminergic neurodegeneration in Parkinson’s models. They also drive local CD4⁺ T cell expansion, which subsequently migrates from gut to brain
www.nature.com/articles/s41...
Intestinal macrophages modulate synucleinopathy along the gut–brain axis - Nature
Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understa...
www.nature.com
January 28, 2026 at 7:25 PM
Our paper is finally out!
We position intestinal muscularis macrophages as early initiators of α-synuclein pathology and dopaminergic neurodegeneration in Parkinson’s models. They also drive local CD4⁺ T cell expansion, which subsequently migrates from gut to brain
www.nature.com/articles/s41...
We position intestinal muscularis macrophages as early initiators of α-synuclein pathology and dopaminergic neurodegeneration in Parkinson’s models. They also drive local CD4⁺ T cell expansion, which subsequently migrates from gut to brain
www.nature.com/articles/s41...
New topical review from Verity Mitchener,
Mille Thackray and Lorena Arancibia-Cárcamo of
@ukdri.ac.uk on the glia-immune network in health and disease, with a focus on how astrocytes and oligodendrocytes coordinate microglia in Alzheimer's disease pathology
Mille Thackray and Lorena Arancibia-Cárcamo of
@ukdri.ac.uk on the glia-immune network in health and disease, with a focus on how astrocytes and oligodendrocytes coordinate microglia in Alzheimer's disease pathology
The glia‐immune network: Astrocytes and oligodendrocytes as microglial co‐ordinators in health and disease
Abstract figure legend The glia-immune network involves the communication(s) of glia via immune signalling pathways. In neuro-homeostasis these pathways have been shown to modulate key processes such...
physoc.onlinelibrary.wiley.com
June 10, 2025 at 1:28 PM
New topical review from Verity Mitchener,
Mille Thackray and Lorena Arancibia-Cárcamo of
@ukdri.ac.uk on the glia-immune network in health and disease, with a focus on how astrocytes and oligodendrocytes coordinate microglia in Alzheimer's disease pathology
Mille Thackray and Lorena Arancibia-Cárcamo of
@ukdri.ac.uk on the glia-immune network in health and disease, with a focus on how astrocytes and oligodendrocytes coordinate microglia in Alzheimer's disease pathology
Reposted by James Conway
Benjamin Ryskeldi-Falcon’s @brfalcon.bsky.social group in the LMB’s Neurobiology Division, with Karen Duff's group at the UK DRI, have discovered that tau filaments are tethered to the membranes of extracellular vesicles in #Alzheimers
Read more: www2.mrc-lmb.cam.ac.uk/cryo-et-reve...
#LMBResearch
Read more: www2.mrc-lmb.cam.ac.uk/cryo-et-reve...
#LMBResearch
November 26, 2024 at 3:54 PM
Benjamin Ryskeldi-Falcon’s @brfalcon.bsky.social group in the LMB’s Neurobiology Division, with Karen Duff's group at the UK DRI, have discovered that tau filaments are tethered to the membranes of extracellular vesicles in #Alzheimers
Read more: www2.mrc-lmb.cam.ac.uk/cryo-et-reve...
#LMBResearch
Read more: www2.mrc-lmb.cam.ac.uk/cryo-et-reve...
#LMBResearch
Reposted by James Conway
🧠Sharing this Starter Pack again as the list has now reached 80 people! A great mix of Profs/PIs/Post-docs/PhDs/Technicians.
Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋
go.bsky.app/S6FfsTp
Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋
go.bsky.app/S6FfsTp
November 19, 2024 at 2:15 PM
🧠Sharing this Starter Pack again as the list has now reached 80 people! A great mix of Profs/PIs/Post-docs/PhDs/Technicians.
Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋
go.bsky.app/S6FfsTp
Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋
go.bsky.app/S6FfsTp