Dr. Jeroen den Dunnen
drdendunnen.bsky.social
Dr. Jeroen den Dunnen
@drdendunnen.bsky.social
Immunologist and Head of Department of CIMM at the Amsterdam UMC, Netherlands. My team studies the role of antibodies during infection and autoimmune diseases, with a particular focus on post-acute infection syndromes (PAIS), such as Long-COVID and ME/CFS.
We already knew that severe acute #COVID19 is induced by pathogenic IgG. But now Lynn Mes & @oliverch77.bsky.social show in @eurjimmunol.bsky.social that IgA2 adds even more fuel to the fire 🔥: onlinelibrary.wiley.com/doi/10.1002/...
Anti‐SARS‐CoV‐2 Spike IgA2 Induces Inflammation by Human Macrophages
Anti-SARS-CoV-2 spike IgA drives inflammation in human macrophages through FcαRI-Syk signaling. IgA2 immune complexes amplify cytokine production and alter glycolysis and mitochondrial function more ....
onlinelibrary.wiley.com
October 7, 2025 at 4:00 PM
Long COVID patients show immunological imprinting and impaired antibody class switching: fewer IgG/IgA antibodies against SARS-CoV-2 spike, but more against seasonal coronaviruses.
Interesting finding by my PhD student Ashwin Mak in J Med Virol: onlinelibrary.wiley.com/doi/10.1002/... 1/6
Seasonal Coronavirus‐Induced Immunological Imprinting and Previous Herpesvirus Infections in Patients With Long COVID
Long COVID (LC) is a post-acute infection syndrome affecting 5%–10% of individuals infected by SARS-CoV-2. Here, we aimed to study SARS-CoV-2 humoral immunity, immunological imprinting by endemic cor...
onlinelibrary.wiley.com
August 30, 2025 at 8:06 PM
Big thanks to @keystonesymposia.bsky.social @virusesimmunity.bsky.social @ahandvanish.bsky.social @daltmann.bsky.social and others for organization of the second #LongCOVID Keystone #KSLongCOVID26. I’ll mention a few personal highlights. 1/
August 13, 2025 at 4:16 PM
Huge congratulations to my talented postdoc @oliverch77.bsky.social on obtaining the prestigious Veni grant! On your way to start your own research group 🙂. www.zonmw.nl/en/news/200-...
200 researchers receive Veni grants | 31 ZonMw projects
Improving the quality of surgery with video analysis. The crosstalk between sodium homeostasis and the gut microbiome. Can nature's microbes keep allergies away
www.zonmw.nl
July 17, 2025 at 5:43 PM
For people that suffer from post-COVID-19 dizziness (as their ONLY symptom), this case report may be of interest to you: casereports.bmj.com/content/18/6.... A tale from personal experience… 1/10
casereports.bmj.com
June 25, 2025 at 9:37 AM
All presentations of the #mecfsconference are now online! Thanks again to @scheibenbogen.bsky.social for organizing this, and bringing so many experts together. Check out the videos at: events.mecfs-research.org/en/events/co.... #MECFS #LongCovid
www.youtube.com/watch?v=k4m4...
Jeroen den Dunnen | International ME/CFS Conference 2025: Autoimmunity as a cause of ME/CFS
YouTube video by MECFS Research Foundation
www.youtube.com
June 13, 2025 at 2:18 PM
My team is very much looking forward to join the @keystonesymposia.bsky.social on #LongCovid and other PAIS (2 talks, 3 posters). Organized by @virusesimmunity.bsky.social @ahandvanish.bsky.social on Aug 10-13 2025 in Santa Fe: www.keystonesymposia.org/conferences/...
Long COVID and Other Post-Acute Infection Syndromes | Keystone Symposia
Join us at the Keystone Symposia on Long COVID and Other Post-Acute Infection Syndromes, August 2025, in Santa Fe, with field leaders!
www.keystonesymposia.org
June 13, 2025 at 2:07 PM
As presented at the International ME/CFS Conference 2025 #mecfsconference, in the @amsterdamumc.bsky.social we will start a clinical trial testing immunoadsorption in Long-COVID. More information about that in this movie: www.youtube.com/watch?v=fE7A... #LongCOVID #MECFS #ZonMw
Amsterdam UMC Long-COVID clinical trial immunoadsorption
YouTube video by Jeroen den Dunnen
www.youtube.com
May 16, 2025 at 12:40 PM
I’m really impressed by the high level of research that was presented at the International ME/CFS Conference 2025 #mecfsconference, organized by the great @scheibenbogen.bsky.social: events.mecfs-research.org/en/events/co.... I’ll mention a few (personal) highlights: 1/7
ME/CFS Research Foundation
ME/CFS Research Foundation is a non-profit organization dedicated to advancing research and understanding of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome.
events.mecfs-research.org
May 13, 2025 at 2:32 PM
It was such a pleasure to have @resiapretorius.bsky.social over @amsterdamumc.bsky.social! Happy to see the #microclots assays worked right away 😀. We can now screen and select #LongCovid patients, to see whether we can also detect microclots using total body PET scan (powered by #ZonMw).
April 13, 2025 at 11:22 AM
In a series of 4 video’s, I was interviewed about our work on #MECFS and post-acute infection syndromes #PAIS (in Dutch). Part one is now online, the others will follow in the next weeks. Big thanks to @mecentraal.bsky.social and the NMCB for arranging this. www.youtube.com/watch?v=em9e...
9/28 Jeroen den Dunnen: 1 - Introductie & onderzoek
YouTube video by ME Centraal
www.youtube.com
April 7, 2025 at 8:12 AM
It’s about time I activate my account on BlueSky. Hi everyone, I’m Jeroen den Dunnen, immunologist and Head of Department @amsterdamumc.bsky.social. I study the function of antibodies in many diseases, but recently I’m mostly known for my work on:
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April 7, 2025 at 8:00 AM