Dr. Dale Bredesen
@drdalebredesen.bsky.social
Dr. Dale Bredesen is the author of The Ageless Brain and The End of Alzheimer's, the Chief Science Officer of Apollo Health, and a pioneer in brain health research.
Clearing beta-amyloid plaques does not repair key brain functions, according to new research on the drug lecanemab. The researchers are, unfortunately, just catching up to what we’ve all known. http://sciencealert.com/one-of-our-biggest-hopes-for-alzheimers-treatment-doesnt-seem-to-work
November 29, 2025 at 5:00 PM
Clearing beta-amyloid plaques does not repair key brain functions, according to new research on the drug lecanemab. The researchers are, unfortunately, just catching up to what we’ve all known. http://sciencealert.com/one-of-our-biggest-hopes-for-alzheimers-treatment-doesnt-seem-to-work
A research team “rebalanced the activity” of a specific set of overactive neurons in the amygdala of mice and found that they reversed the symptoms of anxiety. https://www.sciencedaily.com/releases/2025/11/251104013004.htm
November 26, 2025 at 9:30 PM
A research team “rebalanced the activity” of a specific set of overactive neurons in the amygdala of mice and found that they reversed the symptoms of anxiety. https://www.sciencedaily.com/releases/2025/11/251104013004.htm
Walnuts, which are high in omega-3 fatty acids, polyphenols, flavonoids, and antioxidants, supported focus and memory and improved cognitive function in a new study. For max benefit, consume raw to protect the omega-3 fatty acids. https://foodandwine.com/walnuts-breakfast-brain-health-study-11840393
November 22, 2025 at 7:37 PM
Walnuts, which are high in omega-3 fatty acids, polyphenols, flavonoids, and antioxidants, supported focus and memory and improved cognitive function in a new study. For max benefit, consume raw to protect the omega-3 fatty acids. https://foodandwine.com/walnuts-breakfast-brain-health-study-11840393
Frequent consumption of ultra-processed foods was associated with altered brain structure, and those differences could be part of a feedback loop promoting overeating, according to a study of 30,000 participants. https://sciencedaily.com/releases/2025/10/251020092824.htm
November 21, 2025 at 3:55 PM
Frequent consumption of ultra-processed foods was associated with altered brain structure, and those differences could be part of a feedback loop promoting overeating, according to a study of 30,000 participants. https://sciencedaily.com/releases/2025/10/251020092824.htm
A new device is helping those with advanced age-related macular degeneration see again, and likely provides cognitive protection by supporting brain stimulation. https://www.nbcnews.com/health/health-news/tiny-eye-implant-special-glasses-legally-blind-patients-can-read-rcna238488
November 12, 2025 at 9:15 PM
A new device is helping those with advanced age-related macular degeneration see again, and likely provides cognitive protection by supporting brain stimulation. https://www.nbcnews.com/health/health-news/tiny-eye-implant-special-glasses-legally-blind-patients-can-read-rcna238488
Live from Palm Springs at the California Assisted Living Association Conference! 🌴 Discussing how The Vineyards translates our research into real-life programs for their residents. Learn more about our partnership here: https://lifeatthevineyards.org/cognitive-care
The Vineyards Center for Cognitive Excellence™
The Vineyards dedicated Cognitive Care provides those with Alzheimer’s or other forms of dementia with a positive, stimulating environment.
lifeatthevineyards.org
November 11, 2025 at 9:03 PM
Live from Palm Springs at the California Assisted Living Association Conference! 🌴 Discussing how The Vineyards translates our research into real-life programs for their residents. Learn more about our partnership here: https://lifeatthevineyards.org/cognitive-care
Join Dr. Dale Bredesen and Judy Benjamin this Tuesday, October 28th at 3:00pm PT / 6:00pm ET as we go LIVE to talk about the final stretch of her historic walk across America.
To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_8GTSk8TTRnO8Obn9QN8LhQ
To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_8GTSk8TTRnO8Obn9QN8LhQ
October 27, 2025 at 5:30 PM
Join Dr. Dale Bredesen and Judy Benjamin this Tuesday, October 28th at 3:00pm PT / 6:00pm ET as we go LIVE to talk about the final stretch of her historic walk across America.
To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_8GTSk8TTRnO8Obn9QN8LhQ
To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_8GTSk8TTRnO8Obn9QN8LhQ
Flavanols, found in green tea, berries, broccoli, and other foods, have long been found to reduce cardiovascular disease risk. Now, a study shows flavanol-rich supplements reduced age-related inflammation, likely promoting cognitive health as well. https://doi.org/10.1093/ageing/afaf269
October 23, 2025 at 6:20 PM
Flavanols, found in green tea, berries, broccoli, and other foods, have long been found to reduce cardiovascular disease risk. Now, a study shows flavanol-rich supplements reduced age-related inflammation, likely promoting cognitive health as well. https://doi.org/10.1093/ageing/afaf269
99% of heart attacks and strokes were preceded by at least one of just four risk factors. Unsurprisingly, they are all also connected with cognitive decline. https://www.sciencealert.com/huge-study-links-99-of-heart-attacks-and-strokes-with-four-risk-factors
October 20, 2025 at 7:45 PM
99% of heart attacks and strokes were preceded by at least one of just four risk factors. Unsurprisingly, they are all also connected with cognitive decline. https://www.sciencealert.com/huge-study-links-99-of-heart-attacks-and-strokes-with-four-risk-factors
Tiny protein clusters, called alpha-synuclein oligomers, anti-microbial proteins that may be very early triggers of Parkinson’s disease, have been directly visualized for the first time. https://www.sciencefocus.com/news/hidden-trigger-parkinsons
October 19, 2025 at 6:35 PM
Tiny protein clusters, called alpha-synuclein oligomers, anti-microbial proteins that may be very early triggers of Parkinson’s disease, have been directly visualized for the first time. https://www.sciencefocus.com/news/hidden-trigger-parkinsons
Three researchers won the Nobel Prize for their work on regulatory T cells (Tregs), unraveling how the immune system knows to attack foreign entities and not our own cells. https://www.cnn.com/2025/10/06/science/nobel-prize-medicine-brunkow-ramsdell-sakaguchi-immune-system-intl
October 18, 2025 at 5:20 PM
Three researchers won the Nobel Prize for their work on regulatory T cells (Tregs), unraveling how the immune system knows to attack foreign entities and not our own cells. https://www.cnn.com/2025/10/06/science/nobel-prize-medicine-brunkow-ramsdell-sakaguchi-immune-system-intl
Those who ate the most riboflavin (vitamin B2) cut their dementia risk in half compared to those who ate the least in a new longitudinal study. Folate (B9) and vitamin B6 also reduced risk. https://www.eatingwell.com/riboflavin-for-lower-dementia-risk-study-11824281
October 15, 2025 at 8:28 PM
Those who ate the most riboflavin (vitamin B2) cut their dementia risk in half compared to those who ate the least in a new longitudinal study. Folate (B9) and vitamin B6 also reduced risk. https://www.eatingwell.com/riboflavin-for-lower-dementia-risk-study-11824281
Increasing daytime sleepiness and worsening circadian rest-activity rhythms were associated with a higher risk of dementia. This tiredness could be a symptom of an energy imbalance, where your brain demands more than it is being supplied. https://www.neurology.org/doi/10.1212/WNL.0000000000213403
October 14, 2025 at 6:35 PM
Increasing daytime sleepiness and worsening circadian rest-activity rhythms were associated with a higher risk of dementia. This tiredness could be a symptom of an energy imbalance, where your brain demands more than it is being supplied. https://www.neurology.org/doi/10.1212/WNL.0000000000213403
Women are more likely to develop Alzheimer’s-related dementia than men, but a new study has found that men have higher hospitalization and mortality rates than women following a dementia diagnosis, even after adjusting for age and comorbidities. https://www.medpagetoday.com/neurology/dementia/116964
October 11, 2025 at 5:20 PM
Women are more likely to develop Alzheimer’s-related dementia than men, but a new study has found that men have higher hospitalization and mortality rates than women following a dementia diagnosis, even after adjusting for age and comorbidities. https://www.medpagetoday.com/neurology/dementia/116964
A precise, personalized brain stimulation was found to ease depression rapidly, and even reduced anxiety. The connection between mental health and dementia means this research is worth following. https://newatlas.com/mental-health/hd-tdcs-brain-stimulation-precise-depression/
October 10, 2025 at 3:35 PM
A precise, personalized brain stimulation was found to ease depression rapidly, and even reduced anxiety. The connection between mental health and dementia means this research is worth following. https://newatlas.com/mental-health/hd-tdcs-brain-stimulation-precise-depression/
In a new preprint, Dr. Ram Rao found that the ReCODE protocol significantly reduced depression scores in patients with cognitive impairment.
Read on to learn why ReCODE helps: https://www.apollohealthco.com/precision-medicine-protocol-shows-dual-benefits-improved-cognition-and-reduced-depression/
Read on to learn why ReCODE helps: https://www.apollohealthco.com/precision-medicine-protocol-shows-dual-benefits-improved-cognition-and-reduced-depression/
October 4, 2025 at 8:15 PM
In a new preprint, Dr. Ram Rao found that the ReCODE protocol significantly reduced depression scores in patients with cognitive impairment.
Read on to learn why ReCODE helps: https://www.apollohealthco.com/precision-medicine-protocol-shows-dual-benefits-improved-cognition-and-reduced-depression/
Read on to learn why ReCODE helps: https://www.apollohealthco.com/precision-medicine-protocol-shows-dual-benefits-improved-cognition-and-reduced-depression/
A recent study has found that high sugar intake can increase your risk of dementia by as much as 43%. Researchers also found that genetics can influence these numbers even further. But we already knew that, didn’t we? https://www.eatingwell.com/sugar-dementia-risk-study-11787744
October 3, 2025 at 8:20 PM
A recent study has found that high sugar intake can increase your risk of dementia by as much as 43%. Researchers also found that genetics can influence these numbers even further. But we already knew that, didn’t we? https://www.eatingwell.com/sugar-dementia-risk-study-11787744
We’ve highlighted the link between pollution/toxins and Alzheimer’s for years. Please take precautions, avoid polluted air when possible, use HEPA filters (or similar) in your home, and detox when air quality is low. https://jamanetwork.com/journals/jamaneurology/article-abstract/2838665
October 2, 2025 at 6:00 PM
We’ve highlighted the link between pollution/toxins and Alzheimer’s for years. Please take precautions, avoid polluted air when possible, use HEPA filters (or similar) in your home, and detox when air quality is low. https://jamanetwork.com/journals/jamaneurology/article-abstract/2838665
An antiparasitic used to treat pinworm can help lower the tau levels in mice. The drug targets misshapen nuclear speckles and restores their shape, reducing tau levels without causing cellular stress. https://today.ucsd.edu/story/antiparasitic-drug-shows-power-against-alzheimers-and-dementia
October 1, 2025 at 3:40 PM
An antiparasitic used to treat pinworm can help lower the tau levels in mice. The drug targets misshapen nuclear speckles and restores their shape, reducing tau levels without causing cellular stress. https://today.ucsd.edu/story/antiparasitic-drug-shows-power-against-alzheimers-and-dementia
Join Judy Benjamin and me this Monday, September 29th at 11:00 am PT as we go LIVE to celebrate Judy’s incredible 2,000-mile milestone on her walk across America.
To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_UsefeGqwRTu1XnlFUw905Q#/registration
To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_UsefeGqwRTu1XnlFUw905Q#/registration
September 28, 2025 at 3:00 PM
Join Judy Benjamin and me this Monday, September 29th at 11:00 am PT as we go LIVE to celebrate Judy’s incredible 2,000-mile milestone on her walk across America.
To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_UsefeGqwRTu1XnlFUw905Q#/registration
To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_UsefeGqwRTu1XnlFUw905Q#/registration
Recent research from Brazil showed those consuming the greatest amount of these sweeteners experienced a 62% faster cognitive decline. https://www.medscape.com/viewarticle/sugar-substitutes-not-so-sweet-brain-health-2025a1000nes
September 25, 2025 at 7:00 PM
Recent research from Brazil showed those consuming the greatest amount of these sweeteners experienced a 62% faster cognitive decline. https://www.medscape.com/viewarticle/sugar-substitutes-not-so-sweet-brain-health-2025a1000nes
Can exercise prevent or help treat cancer? According to new research, yes. The study found that a single exercise session of resistance or high-intensity interval training increased anti-cancer myokines and reduced the growth of cancer cells. Wow. https://pmc.ncbi.nlm.nih.gov/articles/PMC12259798/
September 20, 2025 at 6:20 PM
Can exercise prevent or help treat cancer? According to new research, yes. The study found that a single exercise session of resistance or high-intensity interval training increased anti-cancer myokines and reduced the growth of cancer cells. Wow. https://pmc.ncbi.nlm.nih.gov/articles/PMC12259798/
According to Dariush Mozaffarian, the best vegetable (or really, fruit) for heart health is the avocado. It can help lower LDL cholesterol, and provides healthy fiber, potassium, & antioxidants. https://www.realsimple.com/the-one-vegetable-for-better-heart-health-according-to-a-cardiologist-11774184
September 19, 2025 at 5:20 PM
According to Dariush Mozaffarian, the best vegetable (or really, fruit) for heart health is the avocado. It can help lower LDL cholesterol, and provides healthy fiber, potassium, & antioxidants. https://www.realsimple.com/the-one-vegetable-for-better-heart-health-according-to-a-cardiologist-11774184
Looking for a way to put all of your dementia-fighting skills to work? Visiting new locations stimulates your brain, gets you moving, and helps keep you social, helping to keep your brain sharp. https://nypost.com/2025/08/12/health/your-summer-travel-could-be-helping-you-prevent-dementia-heres-how/
September 15, 2025 at 3:22 PM
Looking for a way to put all of your dementia-fighting skills to work? Visiting new locations stimulates your brain, gets you moving, and helps keep you social, helping to keep your brain sharp. https://nypost.com/2025/08/12/health/your-summer-travel-could-be-helping-you-prevent-dementia-heres-how/
A new analysis of the efficacy of lecanemab and donanemab found a high likelihood that the antibodies had no effect for those with 2 copies of APOE4. Given the higher risk of side effects, they recommend these individuals should not receive the treatment. https://pubmed.ncbi.nlm.nih.gov/40225236/
September 13, 2025 at 7:30 PM
A new analysis of the efficacy of lecanemab and donanemab found a high likelihood that the antibodies had no effect for those with 2 copies of APOE4. Given the higher risk of side effects, they recommend these individuals should not receive the treatment. https://pubmed.ncbi.nlm.nih.gov/40225236/