Daniel Fazakerley
@dfazakerley.bsky.social
Assistant Professor at the Institute of Metabolic Science, University of Cambridge, researching insulin action and glucose transporter traffic.
Reposted by Daniel Fazakerley
🚨 pleased to share a new preprint made possible through a fantastic collaboration with the Skala & Palecek labs! can medium composition impact the behavior of hPSC-derived cardiomyocytes? Andy & Aaron co-led efforts to tackle this question w/HPLM! tinyurl.com/ux2arjw8
Human Plasma-Like Medium Promotes Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes
Maturing human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) in vitro is critical for advancing drug discovery and cardiotoxicity screening applications of these cells. However, the metaboli...
tinyurl.com
April 28, 2025 at 4:02 PM
🚨 pleased to share a new preprint made possible through a fantastic collaboration with the Skala & Palecek labs! can medium composition impact the behavior of hPSC-derived cardiomyocytes? Andy & Aaron co-led efforts to tackle this question w/HPLM! tinyurl.com/ux2arjw8
Reposted by Daniel Fazakerley
I'm delighted to be hosting the Cambridge University Endocrinology Society's annual conference this Friday, entitled: 'From Bench to Bedside (and back again)'.
We're really fortunate to have such an exciting line up of speakers, integrating across a wide range of career stages and fields.
We're really fortunate to have such an exciting line up of speakers, integrating across a wide range of career stages and fields.
April 2, 2025 at 5:28 PM
I'm delighted to be hosting the Cambridge University Endocrinology Society's annual conference this Friday, entitled: 'From Bench to Bedside (and back again)'.
We're really fortunate to have such an exciting line up of speakers, integrating across a wide range of career stages and fields.
We're really fortunate to have such an exciting line up of speakers, integrating across a wide range of career stages and fields.
Thanks Jens!
".. most in vitro studies rely on culture protocols that
create metabolic environments far removed from conditions that cells may face in the body" 👇 Great piece!
create metabolic environments far removed from conditions that cells may face in the body" 👇 Great piece!
Pleased to share our @cp-cellmetabolism.bsky.social forum on why we think standard cell culture practices deserve more consideration. How we culture cells has implications for cell metabolism & beyond! With
@jasonrcantor.bsky.social @joycelyntan.bsky.social
authors.elsevier.com/a/1klN65WXUl...
@jasonrcantor.bsky.social @joycelyntan.bsky.social
authors.elsevier.com/a/1klN65WXUl...
March 15, 2025 at 9:06 AM
Thanks Jens!
Reposted by Daniel Fazakerley
Online now: Seeing the world through the eyes of cultured cells
Seeing the world through the eyes of cultured cells
The metabolic environment experienced by cultured cells often differs from physiological conditions. Here, we highlight the effects that the microenvironment can have on cultured cell behavior and advocate for researchers to re-evaluate culture practices…
dlvr.it
March 12, 2025 at 3:42 PM
Online now: Seeing the world through the eyes of cultured cells
We have a postdoc position available in our team to undertake a UKRI-funded project to develop a new cultured skeletal muscle model for studying glc metabolism and insulin action. www.jobs.cam.ac.uk/job/50597/ @ims-mrl.bsky.social Please RT. Please email if interested.
Post-doctoral Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Post-doctoral Research Associate (Fixed Term) in the Department of Clinical Biochemistry at the University of Cambridge.
www.jobs.cam.ac.uk
March 12, 2025 at 6:53 PM
We have a postdoc position available in our team to undertake a UKRI-funded project to develop a new cultured skeletal muscle model for studying glc metabolism and insulin action. www.jobs.cam.ac.uk/job/50597/ @ims-mrl.bsky.social Please RT. Please email if interested.
Pleased to share our @cp-cellmetabolism.bsky.social forum on why we think standard cell culture practices deserve more consideration. How we culture cells has implications for cell metabolism & beyond! With
@jasonrcantor.bsky.social @joycelyntan.bsky.social
authors.elsevier.com/a/1klN65WXUl...
@jasonrcantor.bsky.social @joycelyntan.bsky.social
authors.elsevier.com/a/1klN65WXUl...
March 12, 2025 at 6:40 PM
Pleased to share our @cp-cellmetabolism.bsky.social forum on why we think standard cell culture practices deserve more consideration. How we culture cells has implications for cell metabolism & beyond! With
@jasonrcantor.bsky.social @joycelyntan.bsky.social
authors.elsevier.com/a/1klN65WXUl...
@jasonrcantor.bsky.social @joycelyntan.bsky.social
authors.elsevier.com/a/1klN65WXUl...
Reposted by Daniel Fazakerley
Anyone interested in working with me at Institute of Metabolic Science - Metabolic Research Laboratories, University of Cambridge, on how AMGEN's new obesity drug MariTide works? I have a 3 year postdoc position available! Deadline March 31st! please share www.jobs.cam.ac.uk/job/50529/
Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Research Associate (Fixed Term) in the Department of Clinical Biochemistry at the University of Cambridge.
www.jobs.cam.ac.uk
March 3, 2025 at 3:51 PM
Anyone interested in working with me at Institute of Metabolic Science - Metabolic Research Laboratories, University of Cambridge, on how AMGEN's new obesity drug MariTide works? I have a 3 year postdoc position available! Deadline March 31st! please share www.jobs.cam.ac.uk/job/50529/
Reposted by Daniel Fazakerley
excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!
Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production https://www.biorxiv.org/content/10.1101/2025.02.07.637120v1
February 10, 2025 at 6:40 PM
excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!
Reposted by Daniel Fazakerley
Don’t miss this unique meeting bringing together leading Swedish researchers and practitioners in diabetes to share the latest advancements in diabetes research
👉 lnkd.in/dbbh6vcd
Hope to see you in Umeå!
👉 lnkd.in/dbbh6vcd
Hope to see you in Umeå!
February 7, 2025 at 10:10 PM
Don’t miss this unique meeting bringing together leading Swedish researchers and practitioners in diabetes to share the latest advancements in diabetes research
👉 lnkd.in/dbbh6vcd
Hope to see you in Umeå!
👉 lnkd.in/dbbh6vcd
Hope to see you in Umeå!
Reposted by Daniel Fazakerley
Pleased to announce a BBSRC-funded research associate position in my lab to study resolution of inflammation here in Sheffield. Closing date=13/2, pls get in touch for more info and pls share! www.jobs.ac.uk/job/DLQ588/r... #Drosophila #macrophages #CellBiology @fohsheffield.bsky.social
February 4, 2025 at 10:27 AM
Pleased to announce a BBSRC-funded research associate position in my lab to study resolution of inflammation here in Sheffield. Closing date=13/2, pls get in touch for more info and pls share! www.jobs.ac.uk/job/DLQ588/r... #Drosophila #macrophages #CellBiology @fohsheffield.bsky.social